MIEF1 (mitochondrial elongation factor 1) - Rat Genome Database

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Gene: MIEF1 (mitochondrial elongation factor 1) Pan paniscus
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Symbol: MIEF1
Name: mitochondrial elongation factor 1
RGD ID: 11966614
Description: ENCODES a protein that exhibits mitochondrial large ribosomal subunit binding (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); mitochondrial fusion (ortholog); mitochondrial large ribosomal subunit assembly (ortholog); PARTICIPATES IN mitochondria fission pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); genetic disease (ortholog); Optic Atrophy 14 (ortholog); FOUND IN mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondrial dynamic protein MID51-like; mitochondrial dynamics protein MID51; mitochondrial dynamics protein MIEF1; SMCR7L; Smith-Magenis syndrome chromosome region, candidate 7-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22349,349,448 - 49,369,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,040,839 - 52,056,693 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02220,408,502 - 20,424,327 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12238,228,876 - 38,244,774 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2238,228,939 - 38,244,774 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MIEF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22349,349,448 - 49,369,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,040,839 - 52,056,693 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02220,408,502 - 20,424,327 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12238,228,876 - 38,244,774 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2238,228,939 - 38,244,774 (+)Ensemblpanpan1.1panPan2
MIEF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382239,500,100 - 39,518,132 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2239,499,432 - 39,518,132 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,896,105 - 39,914,137 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,228,230 - 38,244,083 (+)NCBINCBI36Build 36hg18NCBI36
Celera2223,700,340 - 23,716,193 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,862,794 - 22,878,726 (+)NCBIHuRef
CHM1_12239,857,023 - 39,872,876 (+)NCBICHM1_1
T2T-CHM13v2.02239,970,729 - 39,988,762 (+)NCBIT2T-CHM13v2.0
Mief1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391580,118,284 - 80,137,572 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1580,118,219 - 80,137,572 (+)EnsemblGRCm39 Ensembl
GRCm381580,233,964 - 80,253,372 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1580,234,018 - 80,253,371 (+)EnsemblGRCm38mm10GRCm38
MGSCv371580,064,510 - 80,083,801 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361580,061,375 - 80,079,979 (+)NCBIMGSCv36mm8
Celera1582,351,834 - 82,370,715 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.85NCBI
Mief1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87113,666,918 - 113,679,550 (+)NCBIGRCr8
mRatBN7.27111,786,630 - 111,802,220 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,786,709 - 111,802,220 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7113,541,220 - 113,553,854 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,764,757 - 115,777,391 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,734,118 - 115,746,753 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07121,462,962 - 121,478,545 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7121,462,966 - 121,478,546 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07121,451,086 - 121,466,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47118,526,138 - 118,531,814 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17118,560,367 - 118,566,044 (+)NCBI
Celera7108,114,129 - 108,126,760 (+)NCBICelera
Cytogenetic Map7q34NCBI
Mief1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541325,387,399 - 25,401,484 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541325,387,399 - 25,401,484 (+)NCBIChiLan1.0ChiLan1.0
MIEF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11025,534,231 - 25,548,565 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1025,536,288 - 25,546,369 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1025,470,090 - 25,484,439 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01026,285,972 - 26,300,295 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1026,285,988 - 26,300,166 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,000,543 - 26,014,884 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01026,320,077 - 26,334,405 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01026,495,583 - 26,510,147 (-)NCBIUU_Cfam_GSD_1.0
Mief1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,108,151 - 9,120,757 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,117,790 - 2,131,220 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,118,565 - 2,132,181 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MIEF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.158,748,171 - 8,762,087 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,049,362 - 6,061,727 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIEF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11922,072,217 - 22,087,577 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1922,081,838 - 22,085,527 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045103,564,685 - 103,578,229 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mief1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247528,830,485 - 8,841,210 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247528,827,202 - 8,841,278 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000008185   ⟹   ENSPPAP00000001662
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2238,228,939 - 38,244,774 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000008283   ⟹   ENSPPAP00000001686
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2238,237,936 - 38,242,013 (+)Ensembl
RefSeq Acc Id: XM_008975116   ⟹   XP_008973364
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22349,349,448 - 49,369,904 (+)NCBI
NHGRI_mPanPan12252,040,839 - 52,056,693 (+)NCBI
Mhudiblu_PPA_v02220,408,502 - 20,424,327 (+)NCBI
PanPan1.12238,228,876 - 38,244,774 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008973364 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000001662.1
  ENSPPAP00000001686.1
RefSeq Acc Id: XP_008973364   ⟸   XM_008975116
- Sequence:
RefSeq Acc Id: ENSPPAP00000001686   ⟸   ENSPPAT00000008283
RefSeq Acc Id: ENSPPAP00000001662   ⟸   ENSPPAT00000008185

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000007245 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000008185.1 UniProtKB/TrEMBL
  ENSPPAT00000008283.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1410.40 UniProtKB/TrEMBL
  3.30.460.90 UniProtKB/TrEMBL
InterPro Mab-21_dom UniProtKB/TrEMBL
  Mab-21_HhH/H2TH-like UniProtKB/TrEMBL
  MID49/MID51 UniProtKB/TrEMBL
  MID51-like_C UniProtKB/TrEMBL
KEGG Report pps:100987580 UniProtKB/TrEMBL
NCBI Gene MIEF1 ENTREZGENE
PANTHER MITOCHONDRIAL DYNAMICS PROTEIN MID51 UniProtKB/TrEMBL
  PTHR16451 UniProtKB/TrEMBL
Pfam Mab-21_C UniProtKB/TrEMBL
  MID51-like_C UniProtKB/TrEMBL
SMART Mab-21 UniProtKB/TrEMBL
UniProt A0A2R8Z9L3_PANPA UniProtKB/TrEMBL
  A0A2R8ZDM6_PANPA UniProtKB/TrEMBL