USP5 (ubiquitin specific peptidase 5) - Rat Genome Database

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Gene: USP5 (ubiquitin specific peptidase 5) Pan paniscus
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Symbol: USP5
Name: ubiquitin specific peptidase 5
RGD ID: 11966293
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN regulation protein catabolic process at presynapse (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); developmental and epileptic encephalopathy 21 (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,414,488 - 12,429,794 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,411,246 - 12,426,552 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0126,983,941 - 6,998,469 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,895,416 - 6,909,936 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,895,416 - 6,909,936 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
USP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,414,488 - 12,429,794 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,411,246 - 12,426,552 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0126,983,941 - 6,998,469 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,895,416 - 6,909,936 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,895,416 - 6,909,936 (+)Ensemblpanpan1.1panPan2
USP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,852,150 - 6,866,632 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,852,148 - 6,866,632 (+)EnsemblGRCh38hg38GRCh38
GRCh37126,961,314 - 6,975,796 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,831,546 - 6,846,057 (+)NCBINCBI36Build 36hg18NCBI36
Build 34126,831,583 - 6,846,054NCBI
Celera128,578,571 - 8,593,082 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,815,013 - 6,829,524 (+)NCBIHuRef
CHM1_1126,960,283 - 6,974,794 (+)NCBICHM1_1
T2T-CHM13v2.0126,861,449 - 6,875,929 (+)NCBIT2T-CHM13v2.0
Usp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,791,982 - 124,806,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,791,982 - 124,806,447 (-)EnsemblGRCm39 Ensembl
GRCm386124,815,019 - 124,829,484 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,815,019 - 124,829,484 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,765,037 - 124,779,465 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,780,638 - 124,795,066 (-)NCBIMGSCv36mm8
Celera6126,491,148 - 126,505,576 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
Usp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,305,927 - 159,321,345 (-)NCBIGRCr8
mRatBN7.24157,619,663 - 157,634,681 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,847,808 - 163,862,942 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,630,718 - 159,645,852 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,266,340 - 158,281,358 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,332,735 - 157,347,803 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,350,331 - 224,365,479 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,937,706 - 160,952,769 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4146,357,626 - 146,372,628 (-)NCBICelera
Cytogenetic Map4q42NCBI
Usp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,451,622 - 4,466,832 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,451,530 - 4,466,832 (+)NCBIChiLan1.0ChiLan1.0
USP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,158,850 - 38,172,689 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,158,834 - 38,172,071 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,444,116 - 8,457,897 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,511,741 - 38,525,542 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,511,746 - 38,524,959 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,385,805 - 38,399,013 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,426,829 - 38,440,619 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,922,848 - 7,936,630 (+)NCBIUU_Cfam_GSD_1.0
Usp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,284,676 - 102,298,641 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709952,182 - 966,498 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936709952,225 - 966,429 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,843,745 - 63,858,716 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,843,742 - 63,858,835 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,279,250 - 66,294,259 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,885,401 - 6,899,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,885,311 - 6,898,442 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,323,576 - 1,338,147 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,519,113 - 3,532,687 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,519,106 - 3,532,690 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000052654   ⟹   ENSPPAP00000029803
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl126,895,416 - 6,909,936 (+)Ensembl
RefSeq Acc Id: XM_003820274   ⟹   XP_003820322
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21012,414,488 - 12,429,794 (+)NCBI
NHGRI_mPanPan11212,411,246 - 12,426,552 (+)NCBI
Mhudiblu_PPA_v0126,983,941 - 6,998,469 (+)NCBI
PanPan1.1126,895,416 - 6,909,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003820275   ⟹   XP_003820323
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21012,415,301 - 12,429,794 (+)NCBI
NHGRI_mPanPan11212,412,059 - 12,426,552 (+)NCBI
Mhudiblu_PPA_v0126,983,941 - 6,998,469 (+)NCBI
PanPan1.1126,895,416 - 6,909,936 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003820322 (Get FASTA)   NCBI Sequence Viewer  
  XP_003820323 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000029803
  ENSPPAP00000029803.1
RefSeq Acc Id: XP_003820323   ⟸   XM_003820275
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BK98 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003820322   ⟸   XM_003820274
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000029803   ⟸   ENSPPAT00000052654
Protein Domains
UBA   UBP-type   USP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037918 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052654.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
  Ubiquitinyl_hydrolase UniProtKB/TrEMBL
  UBP13_Znf-UBP_var UniProtKB/TrEMBL
  UBP5_UBA1 UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
NCBI Gene USP5 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 UniProtKB/TrEMBL
Pfam UBA UniProtKB/TrEMBL
  UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
  zf-UBP_var UniProtKB/TrEMBL
PIRSF UBP UniProtKB/TrEMBL
PROSITE UBA UniProtKB/TrEMBL
  USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
SMART UBA UniProtKB/TrEMBL
  ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF46934 UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A2R9BK98 ENTREZGENE, UniProtKB/TrEMBL