MYL6B (myosin light chain 6B) - Rat Genome Database

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Gene: MYL6B (myosin light chain 6B) Pan paniscus
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Symbol: MYL6B
Name: myosin light chain 6B
RGD ID: 11961195
Description: ENCODES a protein that exhibits calcium ion binding (inferred); structural constituent of muscle (inferred); ASSOCIATED WITH genetic disease (ortholog); Keloid (ortholog); FOUND IN myosin II complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC117975289; uncharacterized LOC117975289; uncharacterized protein LOC117975289
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,174,424 - 38,180,021 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,171,192 - 38,176,751 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,757,712 - 32,763,287 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11233,008,519 - 33,013,816 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,008,519 - 33,013,816 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
genetic disease  (ISO)
Keloid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MYL6B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,174,424 - 38,180,021 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,171,192 - 38,176,751 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,757,712 - 32,763,287 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11233,008,519 - 33,013,816 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,008,519 - 33,013,816 (-)Ensemblpanpan1.1panPan2
MYL6B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,152,587 - 56,157,982 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,152,256 - 56,159,647 (+)EnsemblGRCh38hg38GRCh38
GRCh371256,546,371 - 56,551,766 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,832,602 - 54,838,038 (+)NCBINCBI36Build 36hg18NCBI36
Celera1256,198,479 - 56,203,915 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1253,585,256 - 53,590,830 (+)NCBIHuRef
CHM1_11256,513,584 - 56,519,154 (+)NCBICHM1_1
T2T-CHM13v2.01256,120,192 - 56,125,594 (+)NCBIT2T-CHM13v2.0
Myl6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,330,026 - 128,334,554 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,330,026 - 128,334,554 (-)EnsemblGRCm39 Ensembl
GRCm3810128,494,157 - 128,498,685 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,494,157 - 128,498,685 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710127,931,213 - 127,935,741 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,897,106 - 127,901,634 (-)NCBIMGSCv36mm8
Celera10130,886,257 - 130,890,611 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.77NCBI
Myl6b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X44,450,733 - 44,451,711 (+)NCBIGRCr8
mRatBN7.2X40,572,012 - 40,572,991 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_UtxX41,884,439 - 41,885,417 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X45,351,761 - 45,352,739 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X43,036,349 - 43,037,327 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X43,831,778 - 43,833,044 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X44,137,223 - 44,138,007 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X62,058,731 - 62,059,471 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX41,236,615 - 41,237,881 (+)NCBICelera
Cytogenetic MapXq21NCBI
Myl6b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,755,936 - 3,760,414 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,755,936 - 3,760,414 (+)NCBIChiLan1.0ChiLan1.0
MYL6B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110472,415 - 476,738 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10472,515 - 476,719 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10535,915 - 541,802 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010481,070 - 486,960 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10481,463 - 489,494 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110458,530 - 464,414 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010701,626 - 707,492 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010825,656 - 831,542 (+)NCBIUU_Cfam_GSD_1.0
Myl6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,303,346 - 58,307,435 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646562,844 - 566,882 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646562,854 - 566,894 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYL6B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,556,061 - 21,558,758 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,554,351 - 21,558,995 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,255,205 - 23,259,847 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103238506
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,090,775 - 52,098,694 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037193,885,609 - 193,891,947 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myl6b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,850,374 - 11,853,904 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,850,368 - 11,854,475 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000050480   ⟹   ENSPPAP00000027638
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1233,008,519 - 33,013,816 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000050487   ⟹   ENSPPAP00000027645
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1233,008,775 - 33,012,330 (-)Ensembl
RefSeq Acc Id: XM_003824934   ⟹   XP_003824982
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,174,424 - 38,180,021 (-)NCBI
NHGRI_mPanPan11238,171,192 - 38,176,751 (-)NCBI
Mhudiblu_PPA_v01232,757,712 - 32,763,218 (-)NCBI
PanPan1.11233,008,519 - 33,013,816 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008978611   ⟹   XP_008976859
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,174,424 - 38,179,906 (-)NCBI
NHGRI_mPanPan11238,171,192 - 38,176,640 (-)NCBI
Mhudiblu_PPA_v01232,759,944 - 32,763,178 (-)NCBI
PanPan1.11233,010,213 - 33,013,664 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008978612   ⟹   XP_008976860
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,174,424 - 38,179,896 (-)NCBI
NHGRI_mPanPan11238,171,192 - 38,176,664 (-)NCBI
Mhudiblu_PPA_v01232,759,944 - 32,763,190 (-)NCBI
PanPan1.11233,010,212 - 33,013,788 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063593428   ⟹   XP_063449498
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,175,288 - 38,179,945 (-)NCBI
RefSeq Acc Id: XM_063593429   ⟹   XP_063449499
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,175,288 - 38,179,906 (-)NCBI
RefSeq Acc Id: XM_063593430   ⟹   XP_063449500
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,175,288 - 38,179,895 (-)NCBI
RefSeq Acc Id: XP_003824982   ⟸   XM_003824934
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BDB5 (UniProtKB/TrEMBL),   A0A2R9BLY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008976860   ⟸   XM_008978612
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BDB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008976859   ⟸   XM_008978611
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BDB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000027638   ⟸   ENSPPAT00000050480
RefSeq Acc Id: ENSPPAP00000027645   ⟸   ENSPPAT00000050487
RefSeq Acc Id: XP_063449498   ⟸   XM_063593428
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063449499   ⟸   XM_063593429
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063449500   ⟸   XM_063593430
- Peptide Label: isoform X1
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036884 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050480.1 UniProtKB/TrEMBL
  ENSPPAT00000050487.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
KEGG Report pps:100977624 UniProtKB/TrEMBL
NCBI Gene MYL6B ENTREZGENE
PANTHER MYOSIN LIGHT CHAIN 1, 3 UniProtKB/TrEMBL
  MYOSIN LIGHT CHAIN 6B UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A2R9BDB5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BLY4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-20 MYL6B  myosin light chain 6B  LOC117975289  uncharacterized LOC117975289  Data merged from RGD:32731020 737654 PROVISIONAL