TPCN2 (two pore segment channel 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: TPCN2 (two pore segment channel 2) Pan paniscus
Analyze
Symbol: TPCN2
Name: two pore segment channel 2
RGD ID: 11956126
Description: ENCODES a protein that exhibits identical protein binding (ortholog); NAADP-sensitive calcium-release channel activity (ortholog); protein kinase binding (ortholog); INVOLVED IN calcium-mediated signaling (ortholog); cellular calcium ion homeostasis (ortholog); lysosome organization (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH intellectual disability (ortholog); Marfanoid Mental Retardation Syndrome, Autosomal (ortholog); Skin/Hair/Eye Pigmentation, Variation In, 10 (ortholog); FOUND IN endosome membrane (ortholog); lysosomal membrane (ortholog); lysosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: two pore calcium channel protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11167,438,635 - 67,478,106 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01164,139,512 - 64,227,913 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
TPCN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11167,438,635 - 67,478,106 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01164,139,512 - 64,227,913 (+)NCBIMhudiblu_PPA_v0panPan3
TPCN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1169,048,932 - 69,136,316 (+)EnsemblGRCh38hg38GRCh38
GRCh381169,048,932 - 69,090,597 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371168,816,400 - 68,858,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361168,572,926 - 68,614,648 (+)NCBINCBI36hg18NCBI36
Build 341168,572,940 - 68,612,568NCBI
Celera1166,156,085 - 66,198,158 (+)NCBI
Cytogenetic Map11q13.3NCBI
HuRef1165,155,518 - 65,197,367 (+)NCBIHuRef
CHM1_11168,700,007 - 68,741,850 (+)NCBICHM1_1
Tpcn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397144,735,370 - 144,837,748 (-)NCBIGRCm39mm39
GRCm39 Ensembl7144,740,261 - 144,837,748 (-)Ensembl
GRCm387145,181,633 - 145,284,011 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7145,186,524 - 145,284,011 (-)EnsemblGRCm38mm10GRCm38
MGSCv377152,439,828 - 152,469,832 (-)NCBIGRCm37mm9NCBIm37
MGSCv367145,063,313 - 145,093,317 (-)NCBImm8
Celera7145,021,844 - 145,051,957 (-)NCBICelera
Cytogenetic Map7F5NCBI
Tpcn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21200,416,538 - 200,446,252 (-)NCBI
Rnor_6.0 Ensembl1218,419,184 - 218,448,877 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01218,419,182 - 218,448,902 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01225,286,480 - 225,316,685 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41205,702,971 - 205,732,664 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11205,857,086 - 205,886,037 (-)NCBI
Celera1197,971,266 - 198,000,753 (-)NCBICelera
Cytogenetic Map1q42NCBI
Tpcn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542216,899,730 - 16,923,962 (-)NCBIChiLan1.0ChiLan1.0
TPCN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11848,956,833 - 48,984,499 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1848,957,249 - 48,984,564 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1847,525,455 - 47,591,712 (-)NCBI
ROS_Cfam_1.01849,592,807 - 49,659,116 (-)NCBI
UMICH_Zoey_3.11849,039,802 - 49,105,897 (-)NCBI
UNSW_CanFamBas_1.01848,625,233 - 48,691,444 (-)NCBI
UU_Cfam_GSD_1.01849,371,799 - 49,438,088 (-)NCBI
Tpcn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049474,875,313 - 4,900,723 (-)NCBI
SpeTri2.0NW_0049365991,301,937 - 1,343,046 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPCN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.124,069,267 - 4,105,065 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.222,709,001 - 2,726,449 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TPCN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.115,491,476 - 5,529,015 (-)NCBI
Vero_WHO_p1.0NW_023666038102,770,203 - 102,810,947 (-)NCBI
Tpcn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476717,877,791 - 17,944,190 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_003828761   ⟹   XP_003828809
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11167,438,635 - 67,478,106 (+)NCBI
Mhudiblu_PPA_v01164,139,515 - 64,180,081 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034933227   ⟹   XP_034789118
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01164,139,513 - 64,227,913 (+)NCBI
RefSeq Acc Id: XM_034933228   ⟹   XP_034789119
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01164,139,512 - 64,227,913 (+)NCBI
RefSeq Acc Id: XR_004665148
RefSeq Status:
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01164,139,616 - 64,227,913 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003828809 (Get FASTA)   NCBI Sequence Viewer  
  XP_034789118 (Get FASTA)   NCBI Sequence Viewer  
  XP_034789119 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003828809   ⟸   XM_003828761
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_034789119   ⟸   XM_034933228
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034789118   ⟸   XM_034933227
- Peptide Label: isoform X1
Protein Domains
Ion_trans


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031099 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000016118 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000016128 UniProtKB/TrEMBL
  ENSPPAP00000016131 UniProtKB/TrEMBL
  ENSPPAP00000016137 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038811 UniProtKB/TrEMBL
  ENSPPAT00000038821 UniProtKB/TrEMBL
  ENSPPAT00000038824 UniProtKB/TrEMBL
  ENSPPAT00000038830 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.350 UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  TPC2 UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100971084 UniProtKB/TrEMBL
NCBI Gene TPCN2 ENTREZGENE
PANTHER PTHR46768 UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
UniProt A0A2R9AFN2_PANPA UniProtKB/TrEMBL
  A0A2R9AFP1_PANPA UniProtKB/TrEMBL
  A0A2R9AGL4_PANPA UniProtKB/TrEMBL
  A0A2R9AGM3_PANPA UniProtKB/TrEMBL