KRT19 (keratin 19) - Rat Genome Database

Name: KRT19
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: KRT19 (keratin 19) Pan paniscus

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Symbol:

KRT19

Name:

keratin 19

RGD ID:

11955954

Description:

ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN cell differentiation involved in embryonic placenta development (ortholog); Notch signaling pathway (ortholog); ASSOCIATED WITH asthma (ortholog); autoimmune disease (ortholog); cholangitis (ortholog); FOUND IN dystrophin-associated glycoprotein complex (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

keratin, type I cytoskeletal 19

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KRT19 (keratin 19)	NCBI	Ortholog
Mus musculus (house mouse):	Krt19 (keratin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Krt19 (keratin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KRT19 (keratin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Krt19 (keratin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KRT19 (keratin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KRT19 (keratin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	23,456,199 - 23,461,175 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	25,346,539 - 25,351,311 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	15,788,355 - 15,793,127 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	16,006,608 - 16,010,782 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	16,006,608 - 16,010,782 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

autoimmune disease (ISO)

cholangitis (ISO)

Chronic Hepatitis (ISO)

Copper-Overload Cirrhosis (ISO)

esophagus squamous cell carcinoma (ISO)

Experimental Liver Cirrhosis (ISO)

hereditary breast ovarian cancer syndrome (ISO)

Neoplasm Invasiveness (ISO)

Neoplastic Cell Transformation (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation involved in embryonic placenta development (IEA,ISO)

epithelial cell differentiation (IEA)

intermediate filament organization (IEA)

Notch signaling pathway (IEA,ISO)

response to estrogen (IEA)

sarcomere organization (IEA)

Cellular Component

apicolateral plasma membrane (IEA)

cell periphery (IEA)

costamere (IEA)

cytoskeleton (IEA)

dystrophin-associated glycoprotein complex (ISO)

intermediate filament (IEA)

plasma membrane (IEA,ISO)

sarcolemma (IEA)

terminal web (IEA)

Z disc (IEA)

Molecular Function

protein binding (ISO)

protein-containing complex binding (ISO)

structural constituent of muscle (IEA)

structural molecule activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

KRT19
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	23,456,199 - 23,461,175 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	25,346,539 - 25,351,311 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	15,788,355 - 15,793,127 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	16,006,608 - 16,010,782 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	16,006,608 - 16,010,782 (+)	Ensembl	panpan1.1		panPan2

KRT19
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	41,523,617 - 41,528,308 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	41,523,617 - 41,528,308 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	39,679,869 - 39,684,560 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	36,933,395 - 36,938,167 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	36,933,395 - 36,938,160	NCBI
Celera	17	36,333,093 - 36,337,867 (-)	NCBI		Celera
Cytogenetic Map	17	q21.2	NCBI
HuRef	17	35,443,484 - 35,448,259 (-)	NCBI		HuRef
CHM1_1	17	39,915,178 - 39,919,959 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	42,379,161 - 42,383,869 (-)	NCBI		T2T-CHM13v2.0

Krt19
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	100,031,636 - 100,036,752 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	100,031,636 - 100,039,491 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	100,140,810 - 100,145,926 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	100,140,810 - 100,148,665 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	100,002,124 - 100,007,233 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	99,956,900 - 99,962,009 (-)	NCBI		MGSCv36	mm8
Celera	11	110,757,190 - 110,762,299 (-)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	63.42	NCBI

Krt19
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	85,576,235 - 85,580,952 (-)	NCBI		GRCr8
mRatBN7.2	10	85,075,835 - 85,080,552 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	85,066,802 - 85,171,799 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	90,093,836 - 90,098,710 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	89,592,194 - 89,596,911 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	84,984,138 - 84,988,855 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	88,055,843 - 88,060,560 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	88,055,841 - 88,060,561 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	87,848,518 - 87,853,235 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	89,080,953 - 89,085,670 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	89,095,322 - 89,100,040 (-)	NCBI
Celera	10	83,795,223 - 83,800,127 (-)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

KRT19
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	21,240,778 - 21,245,039 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	20,702,551 - 20,706,814 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	21,961,705 - 21,965,969 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	9	20,747,715 - 20,751,978 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	21,013,735 - 21,018,001 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	21,117,527 - 21,121,798 (+)	NCBI		UU_Cfam_GSD_1.0

Krt19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	20,630,470 - 20,634,420 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	16,440,693 - 16,444,791 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	16,440,723 - 16,444,679 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KRT19
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	21,115,448 - 21,119,107 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	21,115,453 - 21,119,115 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	21,536,784 - 21,540,278 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KRT19
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	64,714,497 - 64,719,805 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	64,714,970 - 64,719,678 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	35,559,784 - 35,564,785 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003813846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000038642 ⟹ ENSPPAP00000015949

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	16,006,608 - 16,010,782 (+)	Ensembl

RefSeq Acc Id:

XM_003813846 ⟹ XP_003813894

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	19	23,456,199 - 23,461,175 (+)	NCBI
NHGRI_mPanPan1	17	25,346,539 - 25,351,311 (+)	NCBI
Mhudiblu_PPA_v0	17	15,788,355 - 15,793,127 (+)	NCBI
PanPan1.1	17	16,006,608 - 16,010,782 (+)	NCBI

Sequence:

show sequence

CCTGCAAATTCCTCAGGGCTCAGATATCCGCCCCTGACACCATTCCTCCCTTCCCCCCTCCACC
GGCCCCGGGCATAAAAGGCGCCAGGTGAGGGCCTCGCCGCTCCTCCCGCGAATCGCAGCTTCTG
AGACCAGGGTTGCTCCGTCCGTGCTCCGCCTCGCCATGACTTCCTACAGCTATCGCCAGTCGTC
GGCCACGTCGTCCTTCGGAGGCCTGGGCGGCGGCTCCGTGCGTTTTGGGCCGGGGGTCGCCTTT
CGCGCGCCCAGCATTCACGGGGGCTCCGGCGGCCGCGGCGTGTCCGTGTCCTCCGCCCGCTTTG
TGTCCTCGTCCTCCTCGGGGGGCTACGGCGGCGGCTACGGCGGCGTCCTGACCGCGTCCGACGG
GCTGCTGGCTGGCAACGAGAAGCTCACCATGCAGAACCTCAACGACCGCCTGGCCTCCTACCTG
GACAAGGTGCGCGCCCTGGAGGCGGCCAACGGCGAGCTGGAGGTGAAGATCCGCGACTGGTACC
AGAAGCAGGGGCCTGGGCCCTCCCGCGACTACAGCCACTACTACACGACCATCCAGGACCTGCG
GGACAAGATTCTTGGTGCCACCATTGAGAACTCCAGGATTGTTCTGCAGATCGACAATGCCCGT
CTGGCTGCAGATGACTTCCGAACCAAGTTTGAGACGGAACAGGCTCTGCGCATGAGCGTGGAGG
CCGACATCAACGGCCTGCGCAGGGTGCTGGATGAGCTGACCCTGGCCAGGACCGACCTGGAGAT
GCAGATTGAAGGCCTGAAGGAAGAGCTGGCCTACCTGAAGAAGAACCATGAGGAGGAAATCAAT
ACGCTGAGGGGCCAAGTGGGAGGCCAGGTCAGTGTGGAGGTAGATTCCGCTCCGGGCACCGATC
TCGCCAAGATCCTGAGTGACATGCGAAGCCAATATGAGGTCATGGCCGAGCAGAACCGGAAGGA
TGCTGAAGCCTGGTTCACCAGCCGGACTGAAGAATTGAACCGGGAGGTCGCTGGCCACACGGAG
CAGCTCCAGATGAGCAGGTCCGAGGTTACTGACCTGCGGCGCACCCTTCAGGGTCTTGAGATTG
AGCTGCAGTCACAGCTGAGCATGAAAGCTGCCTTGGAAGACACACTGGCAGAAACGGAGGCACG
CTTTGGAGCCCAGCTGGCGCATATCCAGGCGCTGATCAGCGGTATTGAAGCCCAGCTGGGCGAT
GTGCGAGCTGATAGTGAGCGGCAGAATCAGGAGTACCAGCGGCTCATGGACATCAAGTCGCGGC
TGGAGCAGGAGATTGCCACCTACCGCAGCCTGCTCGAGGGACAGGAAGATCACTACAACAATCT
GTCCGCCTCCAAGGTCCTCTGAGGCAGCAGGCTCTGGGGCTTCTGCTGTCCTTTGGAGGGTGTC
TTCTGGGTAGAGGGATGGGAAGGAAGGGACCCTTACCCCCGGCTCTTCTCCTGACCTGCCAATA
AAAATTTATGGTCCAAGGGAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_003813894	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000015949
	ENSPPAP00000015949.1

RefSeq Acc Id:

XP_003813894 ⟸ XM_003813846

- UniProtKB:

A0A2R9ALU5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGGYGGG
YGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYS
HYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDE
LTLARTDLEMQIEGLKEELAYLKKNHEEEINTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQY
EVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAAL
EDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLL
EGQEDHYNNLSASKVL

hide sequence

Ensembl Acc Id:

ENSPPAP00000015949 ⟸ ENSPPAT00000038642

Protein Domains

IF rod

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000031096	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000038642.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.170	UniProtKB/TrEMBL
	Single helix bin	UniProtKB/TrEMBL
	Vasodilator-stimulated phosphoprotein	UniProtKB/TrEMBL
InterPro	IF_conserved	UniProtKB/TrEMBL
	IF_rod_dom	UniProtKB/TrEMBL
	Keratin_I	UniProtKB/TrEMBL
KEGG Report	pps:100977663	UniProtKB/TrEMBL
NCBI Gene	KRT19	ENTREZGENE
PANTHER	KERATIN, TYPE I CYTOSKELETAL 19	UniProtKB/TrEMBL
	PTHR23239	UniProtKB/TrEMBL
Pfam	Filament	UniProtKB/TrEMBL
PRINTS	TYPE1KERATIN	UniProtKB/TrEMBL
PROSITE	IF_ROD_1	UniProtKB/TrEMBL
	IF_ROD_2	UniProtKB/TrEMBL
SMART	Filament	UniProtKB/TrEMBL
Superfamily-SCOP	Intermediate filament protein, coiled coil region	UniProtKB/TrEMBL
	Prefoldin	UniProtKB/TrEMBL
UniProt	A0A2R9ALU5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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