E2F3 (E2F transcription factor 3) - Rat Genome Database

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Gene: E2F3 (E2F transcription factor 3) Pan paniscus
Analyze
Symbol: E2F3
Name: E2F transcription factor 3
RGD ID: 11955605
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of fat cell proliferation (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH genetic disease (ortholog); high grade glioma (ortholog); lung adenocarcinoma (ortholog); FOUND IN nucleus (inferred); RNA polymerase II transcription regulator complex (inferred); transcription regulator complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor E2F3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2535,036,930 - 35,128,398 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1631,036,391 - 31,127,855 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0620,225,471 - 20,317,199 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1620,574,244 - 20,665,785 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl620,574,898 - 20,665,785 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
E2F3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2535,036,930 - 35,128,398 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1631,036,391 - 31,127,855 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0620,225,471 - 20,317,199 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1620,574,244 - 20,665,785 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl620,574,898 - 20,665,785 (+)Ensemblpanpan1.1panPan2
E2F3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38620,401,879 - 20,493,714 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl620,401,879 - 20,493,714 (+)EnsemblGRCh38hg38GRCh38
GRCh37620,402,110 - 20,493,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36620,510,377 - 20,601,921 (+)NCBINCBI36Build 36hg18NCBI36
Build 34620,510,376 - 20,601,921NCBI
Celera621,635,267 - 21,727,062 (+)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef620,346,529 - 20,438,219 (+)NCBIHuRef
CHM1_1620,404,479 - 20,496,262 (+)NCBICHM1_1
T2T-CHM13v2.0620,273,917 - 20,365,731 (+)NCBIT2T-CHM13v2.0
E2f3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391330,090,558 - 30,171,172 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1330,090,558 - 30,170,046 (-)EnsemblGRCm39 Ensembl
GRCm381329,906,575 - 29,986,064 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1329,906,575 - 29,986,063 (-)EnsemblGRCm38mm10GRCm38
MGSCv371329,998,444 - 30,077,932 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361329,917,237 - 29,993,528 (-)NCBIMGSCv36mm8
Celera1330,125,315 - 30,204,809 (-)NCBICelera
Cytogenetic Map13A3.2NCBI
cM Map1313.09NCBI
E2f3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81734,810,355 - 34,887,725 (+)NCBIGRCr8
mRatBN7.21734,601,756 - 34,679,139 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1734,601,830 - 34,676,253 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1734,421,885 - 34,499,059 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01736,025,759 - 36,102,934 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01734,417,688 - 34,494,867 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01736,334,136 - 36,408,831 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1736,334,147 - 36,408,831 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01737,641,855 - 37,716,592 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41741,079,346 - 41,145,568 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1734,130,042 - 34,203,210 (+)NCBICelera
Cytogenetic Map17p12NCBI
E2f3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554836,042,863 - 6,117,479 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554836,039,569 - 6,116,000 (-)NCBIChiLan1.0ChiLan1.0
E2F3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13519,012,646 - 19,086,674 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3519,012,324 - 19,083,634 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3518,971,644 - 19,045,676 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03519,123,558 - 19,197,676 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3519,122,042 - 19,194,624 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13518,931,701 - 19,005,696 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03518,996,668 - 19,070,695 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03520,416,008 - 20,490,009 (+)NCBIUU_Cfam_GSD_1.0
E2f3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049465,947,295 - 6,019,002 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365525,711,923 - 5,783,694 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365525,712,247 - 5,783,643 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
E2F3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl715,794,178 - 15,870,204 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1715,793,519 - 15,870,213 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2716,704,641 - 16,779,074 (+)NCBISscrofa10.2Sscrofa10.2susScr3
E2F3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11751,714,052 - 51,805,827 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604420,694,985 - 20,787,283 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
E2f3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247566,185,366 - 6,266,000 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247566,182,087 - 6,266,097 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000038119   ⟹   ENSPPAP00000015429
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl620,574,898 - 20,662,503 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000038127   ⟹   ENSPPAP00000015437
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl620,576,071 - 20,665,785 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000038130   ⟹   ENSPPAP00000015440
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl620,649,055 - 20,662,503 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000038134   ⟹   ENSPPAP00000015444
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl620,650,731 - 20,662,503 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000038136   ⟹   ENSPPAP00000015446
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl620,654,810 - 20,662,503 (+)Ensembl
RefSeq Acc Id: XM_024929297   ⟹   XP_024785065
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2535,036,930 - 35,128,398 (+)NCBI
NHGRI_mPanPan1631,036,391 - 31,127,855 (+)NCBI
Mhudiblu_PPA_v0620,225,471 - 20,317,199 (+)NCBI
PanPan1.1620,574,244 - 20,665,785 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063605160   ⟹   XP_063461230
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2535,036,930 - 35,128,398 (+)NCBI
RefSeq Acc Id: XM_063605161   ⟹   XP_063461231
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2535,038,055 - 35,128,398 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_024785065   ⟸   XM_024929297
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AIK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000015429   ⟸   ENSPPAT00000038119
RefSeq Acc Id: ENSPPAP00000015446   ⟸   ENSPPAT00000038136
RefSeq Acc Id: ENSPPAP00000015444   ⟸   ENSPPAT00000038134
RefSeq Acc Id: ENSPPAP00000015440   ⟸   ENSPPAT00000038130
RefSeq Acc Id: ENSPPAP00000015437   ⟸   ENSPPAT00000038127
RefSeq Acc Id: XP_063461230   ⟸   XM_063605160
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063461231   ⟸   XM_063605161
- Peptide Label: isoform X3
Protein Domains
E2F transcription factor CC-MB   E2F/DP family winged-helix DNA-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030855 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038119.1 UniProtKB/TrEMBL
  ENSPPAT00000038127.1 UniProtKB/TrEMBL
  ENSPPAT00000038130.1 UniProtKB/TrEMBL
  ENSPPAT00000038134.1 UniProtKB/TrEMBL
  ENSPPAT00000038136.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  6.10.250.540 UniProtKB/TrEMBL
InterPro E2F UniProtKB/TrEMBL
  E2F-DP_heterodim UniProtKB/TrEMBL
  E2F_CC-MB UniProtKB/TrEMBL
  E2F_WHTH_DNA-bd_dom UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene E2F3 ENTREZGENE
PANTHER PTHR12081 UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR E2F3 UniProtKB/TrEMBL
Pfam E2F_CC-MB UniProtKB/TrEMBL
  E2F_TDP UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
SMART E2F_TDP UniProtKB/TrEMBL
Superfamily-SCOP SSF144074 UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
UniProt A0A2R9ADP3_PANPA UniProtKB/TrEMBL
  A0A2R9ADR5_PANPA UniProtKB/TrEMBL
  A0A2R9AEQ5_PANPA UniProtKB/TrEMBL
  A0A2R9AIK4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AIL9_PANPA UniProtKB/TrEMBL