CUL4A (cullin 4A) - Rat Genome Database

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Gene: CUL4A (cullin 4A) Pan paniscus
Analyze
Symbol: CUL4A
Name: cullin 4A
RGD ID: 11955049
Description: ENCODES a protein that exhibits ubiquitin ligase complex scaffold activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); hemopoiesis (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); factor X deficiency (ortholog); genetic disease (ortholog); FOUND IN Cul4A-RING E3 ubiquitin ligase complex (ortholog); cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cullin-4A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214114,713,032 - 114,771,466 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113113,400,061 - 113,457,191 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01394,350,484 - 94,409,183 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113113,428,215 - 113,474,194 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13113,428,271 - 113,472,701 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CUL4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214114,713,032 - 114,771,466 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113113,400,061 - 113,457,191 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01394,350,484 - 94,409,183 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113113,428,215 - 113,474,194 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13113,428,271 - 113,472,701 (+)Ensemblpanpan1.1panPan2
CUL4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813113,208,193 - 113,267,108 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13113,208,193 - 113,267,108 (+)EnsemblGRCh38hg38GRCh38
GRCh3713113,862,507 - 113,921,422 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613112,911,087 - 112,967,393 (+)NCBINCBI36Build 36hg18NCBI36
Build 3413112,911,086 - 112,967,392NCBI
Celera1394,689,332 - 94,746,025 (+)NCBICelera
Cytogenetic Map13q34NCBI
HuRef1394,301,391 - 94,358,301 (+)NCBIHuRef
CHM1_113113,831,366 - 113,888,434 (+)NCBICHM1_1
T2T-CHM13v2.013112,460,539 - 112,520,767 (+)NCBIT2T-CHM13v2.0
Cul4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,155,623 - 13,197,940 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl813,155,621 - 13,197,940 (+)EnsemblGRCm39 Ensembl
GRCm38813,105,623 - 13,147,940 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,105,621 - 13,147,940 (+)EnsemblGRCm38mm10GRCm38
MGSCv37813,105,721 - 13,147,940 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36813,105,720 - 13,147,753 (+)NCBIMGSCv36mm8
Celera813,272,636 - 13,315,964 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.73NCBI
Cul4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81683,086,688 - 83,124,503 (-)NCBIGRCr8
mRatBN7.21676,385,298 - 76,422,316 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1676,384,546 - 76,422,330 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1681,665,849 - 81,702,866 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01685,118,426 - 85,155,443 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01680,367,049 - 80,404,115 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01681,718,784 - 81,756,653 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,719,028 - 81,756,654 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01681,204,989 - 81,242,020 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,242,293 - 81,279,498 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1674,191,398 - 74,228,350 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
Cul4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955404583,261 - 617,914 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955404583,261 - 617,914 (-)NCBIChiLan1.0ChiLan1.0
CUL4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12260,624,215 - 60,667,844 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2260,624,241 - 60,666,616 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2260,336,591 - 60,379,892 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02261,249,926 - 61,292,535 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2261,249,885 - 61,293,566 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12260,748,228 - 60,791,990 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02260,750,419 - 60,794,121 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02260,781,867 - 60,825,233 (+)NCBIUU_Cfam_GSD_1.0
Cul4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945195,519,630 - 195,543,032 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936472408,659 - 432,379 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936472409,083 - 432,442 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CUL4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1178,557,013 - 78,589,193 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11178,557,030 - 78,588,964 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,146,594 - 86,178,480 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUL4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1391,211,238 - 91,267,236 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl391,212,193 - 91,268,838 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604648,249,225 - 48,306,414 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cul4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624793688,135 - 722,490 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624793686,720 - 722,516 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000044819   ⟹   ENSPPAP00000022014
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl13113,428,271 - 113,472,701 (+)Ensembl
RefSeq Acc Id: XM_034937043   ⟹   XP_034792934
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v214114,714,137 - 114,771,466 (+)NCBI
NHGRI_mPanPan113113,401,173 - 113,457,191 (+)NCBI
Mhudiblu_PPA_v01394,351,878 - 94,409,183 (+)NCBI
RefSeq Acc Id: XM_034937044   ⟹   XP_034792935
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v214114,714,724 - 114,771,466 (+)NCBI
NHGRI_mPanPan113113,402,381 - 113,457,191 (+)NCBI
Mhudiblu_PPA_v01394,353,089 - 94,409,167 (+)NCBI
RefSeq Acc Id: XM_057299622   ⟹   XP_057155605
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v214114,713,032 - 114,771,466 (+)NCBI
NHGRI_mPanPan113113,400,061 - 113,457,191 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034792934 (Get FASTA)   NCBI Sequence Viewer  
  XP_034792935 (Get FASTA)   NCBI Sequence Viewer  
  XP_057155605 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000022014.1
Reference Protein Sequences
RefSeq Acc Id: XP_034792934   ⟸   XM_034937043
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034792935   ⟸   XM_034937044
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AXR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000022014   ⟸   ENSPPAT00000044819
RefSeq Acc Id: XP_057155605   ⟸   XM_057299622
- Peptide Label: isoform X2
Protein Domains
Cullin family profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034185 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000044819.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  Cullin Repeats UniProtKB/TrEMBL
InterPro Cullin UniProtKB/TrEMBL
  Cullin_CS UniProtKB/TrEMBL
  Cullin_homology UniProtKB/TrEMBL
  Cullin_homology_sf UniProtKB/TrEMBL
  Cullin_N UniProtKB/TrEMBL
  Cullin_neddylation_domain UniProtKB/TrEMBL
  Cullin_repeat-like_dom_sf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene CUL4A ENTREZGENE
PANTHER CULLIN-4A UniProtKB/TrEMBL
  PTHR11932 UniProtKB/TrEMBL
Pfam Cullin UniProtKB/TrEMBL
  Cullin_Nedd8 UniProtKB/TrEMBL
PROSITE CULLIN_1 UniProtKB/TrEMBL
  CULLIN_2 UniProtKB/TrEMBL
SMART CULLIN UniProtKB/TrEMBL
  Cullin_Nedd8 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF74788 UniProtKB/TrEMBL
  SSF75632 UniProtKB/TrEMBL
UniProt A0A2R9AXR3 ENTREZGENE, UniProtKB/TrEMBL