TSEN54 (tRNA splicing endonuclease subunit 54) - Rat Genome Database

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Gene: TSEN54 (tRNA splicing endonuclease subunit 54) Pan paniscus
Analyze
Symbol: TSEN54
Name: tRNA splicing endonuclease subunit 54
RGD ID: 11952205
Description: INVOLVED IN tRNA processing (inferred); tRNA splicing, via endonucleolytic cleavage and ligation (inferred); tRNA-type intron splice site recognition and cleavage (inferred); PARTICIPATES IN tRNA maturation pathway; ASSOCIATED WITH amblyopia (ortholog); cerebellar hypoplasia (ortholog); Deglutition Disorders (ortholog); FOUND IN tRNA-intron endonuclease complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tRNA splicing endonuclease 54 homolog; tRNA-splicing endonuclease subunit Sen54
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,558,787 - 91,567,891 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,381,051 - 96,390,228 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,465,488 - 69,474,667 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,017,357 - 75,025,166 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,017,351 - 75,025,166 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TSEN54
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,558,787 - 91,567,891 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,381,051 - 96,390,228 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,465,488 - 69,474,667 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,017,357 - 75,025,166 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,017,351 - 75,025,166 (+)Ensemblpanpan1.1panPan2
TSEN54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,516,528 - 75,524,735 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1775,515,944 - 75,524,735 (+)EnsemblGRCh38hg38GRCh38
GRCh371773,512,609 - 73,520,816 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,024,204 - 71,032,415 (+)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map17q25.1NCBI
HuRef1768,936,266 - 68,944,477 (+)NCBIHuRef
CHM1_11773,577,646 - 73,585,857 (+)NCBICHM1_1
T2T-CHM13v2.01776,409,894 - 76,418,101 (+)NCBIT2T-CHM13v2.0
Tsen54
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,704,563 - 115,713,928 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,705,550 - 115,713,920 (+)EnsemblGRCm39 Ensembl
GRCm3811115,813,728 - 115,823,102 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11115,814,724 - 115,823,094 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711115,676,053 - 115,684,416 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,630,829 - 115,639,192 (+)NCBIMGSCv36mm8
Celera11127,575,279 - 127,583,573 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.91NCBI
Tsen54
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,540,479 - 101,549,022 (+)NCBIGRCr8
mRatBN7.210101,041,607 - 101,050,088 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,042,503 - 101,050,087 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,104,319 - 106,111,904 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010105,567,402 - 105,574,987 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010100,963,462 - 100,971,046 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010104,358,401 - 104,366,926 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,359,342 - 104,366,926 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010103,919,097 - 103,927,598 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410105,916,407 - 105,923,991 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1099,617,504 - 99,625,088 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Tsen54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555532,367,480 - 2,376,704 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555532,367,476 - 2,376,704 (+)NCBIChiLan1.0ChiLan1.0
TSEN54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.195,009,468 - 5,016,513 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl95,009,468 - 5,016,483 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,688,912 - 5,695,957 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,679,689 - 5,686,738 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,679,692 - 5,686,708 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,718,818 - 5,725,861 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,828,988 - 5,836,007 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,890,068 - 5,897,113 (-)NCBIUU_Cfam_GSD_1.0
Tsen54
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,658,751 - 5,668,304 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936594744,494 - 753,350 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936594744,531 - 753,350 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSEN54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,847,187 - 5,854,882 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,847,170 - 5,855,791 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TSEN54
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11646,152,547 - 46,162,328 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1646,152,869 - 46,161,379 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,918,134 - 16,927,742 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tsen54
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,320,556 - 5,329,131 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248015,320,482 - 5,329,125 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000064767   ⟹   ENSPPAP00000041840
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1775,017,351 - 75,025,166 (+)Ensembl
RefSeq Acc Id: XM_034942890   ⟹   XP_034798781
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21991,559,630 - 91,567,891 (+)NCBI
NHGRI_mPanPan11796,381,964 - 96,390,228 (+)NCBI
Mhudiblu_PPA_v01769,466,401 - 69,474,667 (+)NCBI
RefSeq Acc Id: XM_034942891   ⟹   XP_034798782
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21991,558,787 - 91,567,891 (+)NCBI
NHGRI_mPanPan11796,381,051 - 96,390,228 (+)NCBI
Mhudiblu_PPA_v01769,465,488 - 69,474,667 (+)NCBI
RefSeq Acc Id: XM_055101528   ⟹   XP_054957503
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21991,559,630 - 91,566,937 (+)NCBI
NHGRI_mPanPan11796,381,964 - 96,389,274 (+)NCBI
RefSeq Acc Id: XM_063599403   ⟹   XP_063455473
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21991,559,630 - 91,566,185 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034798781 (Get FASTA)   NCBI Sequence Viewer  
  XP_034798782 (Get FASTA)   NCBI Sequence Viewer  
  XP_054957503 (Get FASTA)   NCBI Sequence Viewer  
  XP_063455473 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000041840.1
Reference Protein Sequences
RefSeq Acc Id: XP_034798782   ⟸   XM_034942891
- Peptide Label: isoform X4
- UniProtKB: A0A2R9CIT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034798781   ⟸   XM_034942890
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CIT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000041840   ⟸   ENSPPAT00000064767
RefSeq Acc Id: XP_054957503   ⟸   XM_055101528
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063455473   ⟸   XM_063599403
- Peptide Label: isoform X2
Protein Domains
tRNA-splicing endonuclease subunit Sen54 N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043519 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064767.1 UniProtKB/TrEMBL
InterPro tRNA_splic_suSen54 UniProtKB/TrEMBL
  tRNA_splic_suSen54_N UniProtKB/TrEMBL
NCBI Gene TSEN54 ENTREZGENE
PANTHER PTHR21027 UniProtKB/TrEMBL
  TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 UniProtKB/TrEMBL
Pfam tRNA_int_end_N2 UniProtKB/TrEMBL
UniProt A0A2R9CIT3 ENTREZGENE, UniProtKB/TrEMBL