MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2) - Rat Genome Database

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Gene: MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2) Pan paniscus
Analyze
Symbol: MAGI2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
RGD ID: 11949913
Description: ENCODES a protein that exhibits activin receptor binding (ortholog); kinesin binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); clathrin-dependent endocytosis (ortholog); negative regulation of activin receptor signaling pathway (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); anxiety disorder (ortholog); Chromosome 7q11.23 Deletion Syndrome, Distal, 1.2-MB (ortholog); FOUND IN centriole (ortholog); ciliary base (ortholog); extrinsic component of postsynaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17144,143,091 - 145,586,400 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0769,943,704 - 71,395,176 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1783,759,307 - 84,511,987 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl783,758,512 - 84,760,872 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MAGI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17144,143,091 - 145,586,400 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0769,943,704 - 71,395,176 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1783,759,307 - 84,511,987 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl783,758,512 - 84,760,872 (-)Ensemblpanpan1.1panPan2
MAGI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38778,017,055 - 79,453,667 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl778,017,055 - 79,453,667 (-)EnsemblGRCh38hg38GRCh38
GRCh37777,646,372 - 79,082,983 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36777,484,310 - 78,920,826 (-)NCBINCBI36Build 36hg18NCBI36
Build 34777,291,048 - 78,727,541NCBI
Celera772,346,978 - 73,783,869 (-)NCBICelera
Cytogenetic Map7q21.11NCBI
HuRef772,249,405 - 73,685,020 (-)NCBIHuRef
CHM1_1777,576,560 - 79,013,089 (-)NCBICHM1_1
T2T-CHM13v2.0779,268,893 - 80,705,470 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2776,978,436 - 78,414,480 (-)NCBI
Magi2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39519,431,787 - 20,909,790 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl519,432,034 - 20,909,790 (+)EnsemblGRCm39 Ensembl
GRCm38519,219,387 - 20,704,792 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl519,227,036 - 20,704,792 (+)EnsemblGRCm38mm10GRCm38
MGSCv37518,732,864 - 20,210,610 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36518,738,799 - 20,216,616 (+)NCBIMGSCv36mm8
Celera516,180,595 - 17,665,978 (+)NCBICelera
Cytogenetic Map5A3NCBI
cM Map58.6NCBI
Magi2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8415,278,518 - 16,762,427 (-)NCBIGRCr8
mRatBN7.2414,386,389 - 15,870,036 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl414,386,399 - 15,870,240 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx419,521,700 - 20,999,622 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0415,323,728 - 16,811,259 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0413,707,338 - 15,197,475 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0410,995,241 - 12,472,423 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl410,995,234 - 11,610,518 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0410,987,831 - 12,456,502 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.449,909,448 - 11,441,301 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1410,054,955 - 11,441,302 (-)NCBI
Celera49,948,183 - 11,419,535 (-)NCBICelera
Cytogenetic Map4q11NCBI
Magi2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554106,400,242 - 7,294,924 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554106,739,115 - 7,295,027 (+)NCBIChiLan1.0ChiLan1.0
MAGI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11817,973,058 - 19,098,785 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1817,918,928 - 18,930,059 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1817,565,936 - 18,971,443 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01818,307,564 - 19,031,590 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1818,283,692 - 19,747,053 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11818,054,185 - 19,371,256 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01817,997,659 - 18,302,395 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01818,251,940 - 19,581,985 (-)NCBIUU_Cfam_GSD_1.0
Magi2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511860,250,078 - 60,938,785 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647921,373,746 - 21,920,214 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647921,373,917 - 22,062,498 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAGI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9100,847,013 - 102,170,004 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19100,846,693 - 102,171,199 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29112,312,166 - 112,574,012 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAGI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12169,460,345 - 70,916,684 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604233,007,517 - 34,474,279 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Magi2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473927,134,993 - 28,430,686 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473927,132,533 - 28,430,765 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000053277   ⟹   ENSPPAP00000030416
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl783,758,512 - 84,760,872 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053316   ⟹   ENSPPAP00000030454
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl783,758,700 - 84,760,872 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053320   ⟹   ENSPPAP00000030458
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl783,758,700 - 84,760,872 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053334   ⟹   ENSPPAP00000030472
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl783,759,550 - 84,760,872 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053373   ⟹   ENSPPAP00000030511
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl783,817,690 - 84,083,782 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053378   ⟹   ENSPPAP00000030516
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl783,818,538 - 84,083,782 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053392   ⟹   ENSPPAP00000030529
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl783,818,538 - 84,083,782 (-)Ensembl
RefSeq Acc Id: XM_034964325   ⟹   XP_034820216
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBI
NHGRI_mPanPan17144,143,091 - 145,586,400 (-)NCBI
Mhudiblu_PPA_v0769,943,704 - 71,395,176 (-)NCBI
RefSeq Acc Id: XM_034964326   ⟹   XP_034820217
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBI
NHGRI_mPanPan17144,143,091 - 145,586,400 (-)NCBI
Mhudiblu_PPA_v0769,943,706 - 71,395,176 (-)NCBI
RefSeq Acc Id: XM_034964327   ⟹   XP_034820218
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,881,175 - 97,322,027 (-)NCBI
NHGRI_mPanPan17144,145,814 - 145,586,385 (-)NCBI
Mhudiblu_PPA_v0769,946,421 - 71,395,103 (-)NCBI
RefSeq Acc Id: XM_034964328   ⟹   XP_034820219
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,881,235 - 97,322,027 (-)NCBI
NHGRI_mPanPan17144,145,873 - 145,586,385 (-)NCBI
Mhudiblu_PPA_v0769,946,494 - 71,395,104 (-)NCBI
RefSeq Acc Id: XM_034964329   ⟹   XP_034820220
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,881,235 - 97,322,027 (-)NCBI
NHGRI_mPanPan17144,145,873 - 145,586,385 (-)NCBI
Mhudiblu_PPA_v0769,946,488 - 71,395,104 (-)NCBI
RefSeq Acc Id: XM_063605939   ⟹   XP_063462009
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBI
RefSeq Acc Id: XM_063605940   ⟹   XP_063462010
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBI
RefSeq Acc Id: XM_063605942   ⟹   XP_063462012
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBI
RefSeq Acc Id: XM_063605943   ⟹   XP_063462013
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBI
RefSeq Acc Id: XM_063605944   ⟹   XP_063462014
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBI
RefSeq Acc Id: XM_063605945   ⟹   XP_063462015
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 97,322,027 (-)NCBI
RefSeq Acc Id: XM_063605946   ⟹   XP_063462016
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 96,633,547 (-)NCBI
RefSeq Acc Id: XM_063605947   ⟹   XP_063462017
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,878,453 - 96,433,777 (-)NCBI
RefSeq Acc Id: XR_004672522
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2695,881,272 - 97,322,027 (-)NCBI
NHGRI_mPanPan17144,145,910 - 145,586,385 (-)NCBI
Mhudiblu_PPA_v0769,946,530 - 71,395,104 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034820216   ⟸   XM_034964325
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BL89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820217   ⟸   XM_034964326
- Peptide Label: isoform X6
- UniProtKB: A0A2R9BM28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820218   ⟸   XM_034964327
- Peptide Label: isoform X10
- UniProtKB: A0A2R9BPX4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820220   ⟸   XM_034964329
- Peptide Label: isoform X13
- UniProtKB: A0A2R9BPX4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820219   ⟸   XM_034964328
- Peptide Label: isoform X12
- UniProtKB: A0A2R9BPX4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000030416   ⟸   ENSPPAT00000053277
RefSeq Acc Id: ENSPPAP00000030516   ⟸   ENSPPAT00000053378
RefSeq Acc Id: ENSPPAP00000030511   ⟸   ENSPPAT00000053373
RefSeq Acc Id: ENSPPAP00000030454   ⟸   ENSPPAT00000053316
RefSeq Acc Id: ENSPPAP00000030458   ⟸   ENSPPAT00000053320
RefSeq Acc Id: ENSPPAP00000030472   ⟸   ENSPPAT00000053334
RefSeq Acc Id: ENSPPAP00000030529   ⟸   ENSPPAT00000053392
RefSeq Acc Id: XP_063462013   ⟸   XM_063605943
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063462010   ⟸   XM_063605940
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063462015   ⟸   XM_063605945
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063462012   ⟸   XM_063605942
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063462014   ⟸   XM_063605944
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063462009   ⟸   XM_063605939
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063462016   ⟸   XM_063605946
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063462017   ⟸   XM_063605947
- Peptide Label: isoform X11
Protein Domains
Guanylate kinase-like   PDZ   WW


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038074 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000053277.1 UniProtKB/TrEMBL
  ENSPPAT00000053316.1 UniProtKB/TrEMBL
  ENSPPAT00000053320.1 UniProtKB/TrEMBL
  ENSPPAT00000053334.1 UniProtKB/TrEMBL
  ENSPPAT00000053373.1 UniProtKB/TrEMBL
  ENSPPAT00000053378.1 UniProtKB/TrEMBL
  ENSPPAT00000053392.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.70.10 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
  Guanylate Kinase phosphate binding domain UniProtKB/TrEMBL
InterPro GK/Ca_channel_bsu UniProtKB/TrEMBL
  Guanylate_kin-like_dom UniProtKB/TrEMBL
  Guanylate_kinase_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
NCBI Gene MAGI2 ENTREZGENE
PANTHER MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED UniProtKB/TrEMBL
  PTHR10316:SF27 UniProtKB/TrEMBL
Pfam Guanylate_kin UniProtKB/TrEMBL
  MAGI_u1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PF00397 UniProtKB/TrEMBL
PROSITE GUANYLATE_KINASE_1 UniProtKB/TrEMBL
  GUANYLATE_KINASE_2 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
SMART GuKc UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  SM00456 UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/TrEMBL
  SSF51045 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9BL89 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BLG7_PANPA UniProtKB/TrEMBL
  A0A2R9BM28 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BPX4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BV33_PANPA UniProtKB/TrEMBL
  A0A2R9BVF8_PANPA UniProtKB/TrEMBL
  A0A2R9BVG5_PANPA UniProtKB/TrEMBL