MALT1 (MALT1 paracaspase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: MALT1 (MALT1 paracaspase) Pan paniscus
Analyze
Symbol: MALT1
Name: MALT1 paracaspase
RGD ID: 11949378
Description: ENCODES a protein that exhibits kinase activator activity (ortholog); protease binding (ortholog); small molecule binding (ortholog); INVOLVED IN B cell activation (ortholog); B-1 B cell differentiation (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIPATES IN nuclear factor kappa B signaling pathway; ASSOCIATED WITH diffuse large B-cell lymphoma (ortholog); genetic disease (ortholog); immunodeficiency 12 (ortholog); FOUND IN polkadots (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21776,210,829 - 76,295,818 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11861,903,645 - 61,988,504 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01852,060,878 - 52,141,985 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11855,395,462 - 55,473,574 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1855,395,462 - 55,473,574 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MALT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21776,210,829 - 76,295,818 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11861,903,645 - 61,988,504 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01852,060,878 - 52,141,985 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11855,395,462 - 55,473,574 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1855,395,462 - 55,473,574 (+)Ensemblpanpan1.1panPan2
MALT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381858,671,465 - 58,754,477 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1858,671,465 - 58,754,477 (+)EnsemblGRCh38hg38GRCh38
GRCh371856,338,697 - 56,421,709 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361854,489,598 - 54,568,350 (+)NCBINCBI36Build 36hg18NCBI36
Build 341854,489,597 - 54,568,350NCBI
Celera1853,055,193 - 53,133,688 (+)NCBICelera
Cytogenetic Map18q21.32NCBI
HuRef1853,046,774 - 53,125,499 (+)NCBIHuRef
CHM1_11856,333,855 - 56,412,584 (+)NCBICHM1_1
T2T-CHM13v2.01858,872,604 - 58,955,588 (+)NCBIT2T-CHM13v2.0
Malt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391865,564,010 - 65,612,138 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1865,564,009 - 65,612,138 (+)EnsemblGRCm39 Ensembl
GRCm381865,430,939 - 65,478,888 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1865,430,938 - 65,479,067 (+)EnsemblGRCm38mm10GRCm38
MGSCv371865,590,651 - 65,638,446 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361865,556,366 - 65,604,161 (+)NCBIMGSCv36mm8
Celera1866,699,207 - 66,748,598 (+)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1838.56NCBI
Malt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81861,212,290 - 61,266,272 (+)NCBIGRCr8
mRatBN7.21858,942,282 - 58,996,318 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1858,942,299 - 58,994,260 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01861,108,712 - 61,162,446 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1861,109,069 - 61,162,445 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01860,305,085 - 60,358,786 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41861,708,388 - 61,760,004 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11861,720,756 - 61,832,919 (+)NCBI
Celera1857,070,977 - 57,125,050 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Malt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540242,911,649 - 42,972,429 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540242,919,480 - 42,968,873 (+)NCBIChiLan1.0ChiLan1.0
MALT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1117,351,458 - 17,412,591 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl117,354,926 - 17,403,927 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha118,335,003 - 18,396,343 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0117,231,245 - 17,291,704 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl117,232,316 - 17,291,990 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1117,292,714 - 17,350,173 (-)NCBIUMICH_Zoey_3.1
UMICH_Zoey_3.1117,272,403 - 17,281,013 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0117,187,356 - 17,248,249 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0117,455,416 - 17,516,194 (-)NCBIUU_Cfam_GSD_1.0
Malt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494430,615,326 - 30,665,178 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364975,853,870 - 5,904,266 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364975,854,361 - 5,910,719 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MALT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1162,076,955 - 162,144,880 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11162,076,933 - 162,144,915 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21179,571,906 - 179,706,232 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MALT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11820,984,985 - 21,064,198 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1820,985,819 - 21,054,554 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660604,506,132 - 4,584,611 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Malt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247924,148,453 - 4,217,548 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247924,148,258 - 4,223,431 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000051331   ⟹   ENSPPAP00000028484
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1855,395,462 - 55,473,574 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000051336   ⟹   ENSPPAP00000028489
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1855,397,327 - 55,471,282 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000051338   ⟹   ENSPPAP00000028491
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1855,402,385 - 55,471,282 (+)Ensembl
RefSeq Acc Id: XM_034943825   ⟹   XP_034799716
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21776,210,829 - 76,295,818 (+)NCBI
NHGRI_mPanPan11861,903,645 - 61,988,504 (+)NCBI
Mhudiblu_PPA_v01852,060,878 - 52,141,985 (+)NCBI
RefSeq Acc Id: XM_034943826   ⟹   XP_034799717
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21776,210,829 - 76,295,818 (+)NCBI
NHGRI_mPanPan11861,903,645 - 61,988,504 (+)NCBI
Mhudiblu_PPA_v01852,061,024 - 52,141,984 (+)NCBI
RefSeq Acc Id: XM_063597343   ⟹   XP_063453413
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21776,210,830 - 76,295,818 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034799716 (Get FASTA)   NCBI Sequence Viewer  
  XP_034799717 (Get FASTA)   NCBI Sequence Viewer  
  XP_063453413 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028484.1
  ENSPPAP00000028489.1
  ENSPPAP00000028491.1
Reference Protein Sequences
RefSeq Acc Id: XP_034799716   ⟸   XM_034943825
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BPB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034799717   ⟸   XM_034943826
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BPB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000028491   ⟸   ENSPPAT00000051338
RefSeq Acc Id: ENSPPAP00000028489   ⟸   ENSPPAT00000051336
RefSeq Acc Id: ENSPPAP00000028484   ⟸   ENSPPAT00000051331
RefSeq Acc Id: XP_063453413   ⟸   XM_063597343
- Peptide Label: isoform X3
Protein Domains
Caspase family p20   Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037274 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051331.1 UniProtKB/TrEMBL
  ENSPPAT00000051336.1 UniProtKB/TrEMBL
  ENSPPAT00000051338.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  2.60.40.3360 UniProtKB/TrEMBL
  3.40.50.1460 UniProtKB/TrEMBL
InterPro Caspase-like_dom_sf UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  MALT1 UniProtKB/TrEMBL
  MALT1_Ig UniProtKB/TrEMBL
  Pept_C14_caspase UniProtKB/TrEMBL
  Pept_C14_p20 UniProtKB/TrEMBL
NCBI Gene MALT1 ENTREZGENE
PANTHER MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE UniProtKB/TrEMBL
  PTHR22576:SF40 UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  MALT1_Ig UniProtKB/TrEMBL
  Peptidase_C14 UniProtKB/TrEMBL
PROSITE CASPASE_P20 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF52129 UniProtKB/TrEMBL
UniProt A0A2R9BFR3_PANPA UniProtKB/TrEMBL
  A0A2R9BFR7_PANPA UniProtKB/TrEMBL
  A0A2R9BPB9 ENTREZGENE, UniProtKB/TrEMBL