CAND1 (cullin associated and neddylation dissociated 1) - Rat Genome Database

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Pathways
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Gene: CAND1 (cullin associated and neddylation dissociated 1) Pan paniscus
Analyze
Symbol: CAND1
Name: cullin associated and neddylation dissociated 1
RGD ID: 11944513
Description: ENCODES a protein that exhibits TBP-class protein binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of RNA polymerase II transcription preinitiation complex assembly (ortholog); PARTICIPATES IN neddylation pathway; ASSOCIATED WITH genetic disease (ortholog); prostate cancer (ortholog); FOUND IN cullin-RING ubiquitin ligase complex (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cullin-associated NEDD8-dissociated protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21027,037,080 - 27,084,905 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11227,033,844 - 27,080,879 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01221,592,833 - 21,638,382 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11222,099,962 - 22,145,013 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1222,099,962 - 22,145,013 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CAND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21027,037,080 - 27,084,905 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11227,033,844 - 27,080,879 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01221,592,833 - 21,638,382 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11222,099,962 - 22,145,013 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1222,099,962 - 22,145,013 (-)Ensemblpanpan1.1panPan2
CAND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381267,269,358 - 67,319,953 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1267,269,358 - 67,319,953 (+)EnsemblGRCh38hg38GRCh38
GRCh371267,663,138 - 67,713,733 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361265,949,416 - 65,994,189 (+)NCBINCBI36Build 36hg18NCBI36
Build 341265,949,415 - 65,994,187NCBI
Celera1267,327,070 - 67,372,407 (+)NCBICelera
Cytogenetic Map12q14.3-q15NCBI
HuRef1264,713,845 - 64,759,496 (+)NCBIHuRef
CHM1_11267,630,340 - 67,675,666 (+)NCBICHM1_1
T2T-CHM13v2.01267,248,745 - 67,299,478 (+)NCBIT2T-CHM13v2.0
Cand1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910119,034,717 - 119,075,960 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10119,035,160 - 119,075,960 (-)EnsemblGRCm39 Ensembl
GRCm3810119,198,812 - 119,240,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10119,199,255 - 119,240,055 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710118,635,868 - 118,677,111 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610118,601,872 - 118,724,036 (-)NCBIMGSCv36mm8
Celera10121,557,633 - 121,598,810 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1067.08NCBI
Cand1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8756,566,765 - 56,604,653 (-)NCBIGRCr8
mRatBN7.2754,681,114 - 54,719,002 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl754,680,900 - 54,718,993 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx756,587,617 - 56,625,505 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0758,790,753 - 58,828,639 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0758,568,597 - 58,606,483 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0762,124,362 - 62,162,451 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl762,124,362 - 62,162,453 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0762,113,404 - 62,151,493 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4758,461,205 - 58,499,092 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1758,481,934 - 58,519,822 (-)NCBI
Celera751,445,526 - 51,483,413 (-)NCBICelera
Cytogenetic Map7q22NCBI
Cand1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545813,815,819 - 13,850,007 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545813,815,819 - 13,850,007 (+)NCBIChiLan1.0ChiLan1.0
CAND1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1109,652,176 - 9,683,373 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl109,641,732 - 9,680,118 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha109,571,760 - 9,612,014 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0109,755,181 - 9,795,481 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl109,755,061 - 9,794,999 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1109,631,961 - 9,672,240 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0109,877,617 - 9,917,882 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0109,999,578 - 10,039,865 (+)NCBIUU_Cfam_GSD_1.0
Cand1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494548,854,528 - 48,892,090 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365455,218,407 - 5,255,245 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365455,217,947 - 5,255,596 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl531,675,574 - 31,696,887 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1531,657,508 - 31,700,163 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2534,955,840 - 34,994,724 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11162,923,198 - 62,968,789 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1162,922,885 - 62,966,994 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037182,746,329 - 182,791,692 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cand1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248021,014,515 - 1,049,561 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248021,010,749 - 1,049,253 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000043425   ⟹   ENSPPAP00000020630
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1222,099,962 - 22,145,013 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000043429   ⟹   ENSPPAP00000020634
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1222,101,821 - 22,135,145 (-)Ensembl
RefSeq Acc Id: XM_003824783   ⟹   XP_003824831
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21027,037,080 - 27,084,905 (-)NCBI
NHGRI_mPanPan11227,033,844 - 27,080,879 (-)NCBI
Mhudiblu_PPA_v01221,592,833 - 21,638,378 (-)NCBI
PanPan1.11222,099,962 - 22,145,013 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034935484   ⟹   XP_034791375
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21027,040,252 - 27,084,905 (-)NCBI
NHGRI_mPanPan11227,037,016 - 27,080,879 (-)NCBI
Mhudiblu_PPA_v01221,595,858 - 21,638,382 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003824831 (Get FASTA)   NCBI Sequence Viewer  
  XP_034791375 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000020630.1
  ENSPPAP00000020634.1
Reference Protein Sequences
RefSeq Acc Id: XP_003824831   ⟸   XM_003824783
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AXS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034791375   ⟸   XM_034935484
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AXS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000020630   ⟸   ENSPPAT00000043425
RefSeq Acc Id: ENSPPAP00000020634   ⟸   ENSPPAT00000043429
Protein Domains
TATA-binding protein interacting (TIP20)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033470 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043425.1 UniProtKB/TrEMBL
  ENSPPAT00000043429.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  CAND1/CAND2 UniProtKB/TrEMBL
  TATA-bd_TIP120 UniProtKB/TrEMBL
NCBI Gene CAND1 ENTREZGENE
PANTHER CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 UniProtKB/TrEMBL
  PTHR12696 UniProtKB/TrEMBL
Pfam HEAT_EZ UniProtKB/TrEMBL
  TIP120 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A2R9AXS4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AZU7_PANPA UniProtKB/TrEMBL