SLC7A6 (solute carrier family 7 member 6) - Rat Genome Database

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Gene: SLC7A6 (solute carrier family 7 member 6) Pan paniscus
Analyze
Symbol: SLC7A6
Name: solute carrier family 7 member 6
RGD ID: 11943035
Description: ENCODES a protein that exhibits arginine binding (inferred); basic amino acid transmembrane transporter activity (inferred); L-amino acid transmembrane transporter activity (inferred); INVOLVED IN nitric oxide biosynthetic process (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Y+L amino acid transporter 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,811,895 - 77,848,511 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11683,722,908 - 83,759,847 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01648,641,256 - 48,675,347 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11668,037,206 - 68,072,502 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1668,038,696 - 68,072,502 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC7A6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,811,895 - 77,848,511 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11683,722,908 - 83,759,847 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01648,641,256 - 48,675,347 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11668,037,206 - 68,072,502 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1668,038,696 - 68,072,502 (+)Ensemblpanpan1.1panPan2
SLC7A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381668,264,526 - 68,301,819 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1668,264,516 - 68,301,823 (+)EnsemblGRCh38hg38GRCh38
GRCh371668,298,429 - 68,335,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,855,924 - 66,893,223 (+)NCBINCBI36Build 36hg18NCBI36
Build 341666,855,933 - 66,893,222NCBI
Celera1652,806,916 - 52,844,230 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1654,171,419 - 54,208,888 (+)NCBIHuRef
CHM1_11669,706,452 - 69,743,751 (+)NCBICHM1_1
T2T-CHM13v2.01674,060,279 - 74,097,601 (+)NCBIT2T-CHM13v2.0
Slc7a6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,894,718 - 106,925,346 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,895,489 - 106,925,338 (+)EnsemblGRCm39 Ensembl
GRCm388106,168,219 - 106,198,714 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8106,168,857 - 106,198,706 (+)EnsemblGRCm38mm10GRCm38
MGSCv378108,692,775 - 108,722,604 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368109,058,004 - 109,087,833 (+)NCBIMGSCv36mm8
Celera8110,396,649 - 110,426,481 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.1NCBI
Slc7a6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,982,459 - 51,010,140 (+)NCBIGRCr8
mRatBN7.21934,073,472 - 34,100,268 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1934,074,286 - 34,100,268 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,899,201 - 40,915,837 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,552,514 - 41,569,150 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,851,657 - 43,868,294 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01938,152,225 - 38,179,149 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,162,515 - 38,179,149 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01949,013,758 - 49,045,949 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41936,032,750 - 36,049,384 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11936,027,483 - 36,054,258 (+)NCBI
Celera1933,510,719 - 33,527,353 (+)NCBICelera
Cytogenetic Map19q12NCBI
Slc7a6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554848,349,622 - 8,383,475 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554848,335,508 - 8,383,814 (-)NCBIChiLan1.0ChiLan1.0
SLC7A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,229,251 - 81,267,325 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,231,680 - 81,252,295 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,219,398 - 81,257,388 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0581,664,241 - 81,702,242 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl581,664,376 - 81,699,724 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1581,490,980 - 81,528,956 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,173,484 - 81,211,387 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0581,814,920 - 81,852,921 (-)NCBIUU_Cfam_GSD_1.0
Slc7a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934940,965,655 - 41,002,149 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647518,586,931 - 18,625,137 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647518,587,058 - 18,624,757 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC7A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1628,834,797 - 28,876,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SLC7A6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,118,131 - 59,164,659 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl559,119,827 - 59,143,982 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604721,852,528 - 21,892,942 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc7a6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,013,340 - 18,032,390 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474618,009,078 - 18,046,072 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000057986   ⟹   ENSPPAP00000035100
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1668,038,696 - 68,072,502 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000057991   ⟹   ENSPPAP00000035105
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1668,045,757 - 68,070,445 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000057994   ⟹   ENSPPAP00000035108
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1668,045,757 - 68,061,907 (+)Ensembl
RefSeq Acc Id: XM_063597693   ⟹   XP_063453763
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21877,811,895 - 77,848,511 (+)NCBI
RefSeq Acc Id: XM_063597694   ⟹   XP_063453764
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21877,811,897 - 77,848,511 (+)NCBI
RefSeq Acc Id: XR_010110275
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21877,811,895 - 77,848,511 (+)NCBI
Protein Sequences
Protein RefSeqs XP_063453763 (Get FASTA)   NCBI Sequence Viewer  
  XP_063453764 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000035100.1
  ENSPPAP00000035105.1
  ENSPPAP00000035108.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000035100   ⟸   ENSPPAT00000057986
RefSeq Acc Id: ENSPPAP00000035105   ⟸   ENSPPAT00000057991
RefSeq Acc Id: ENSPPAP00000035108   ⟸   ENSPPAT00000057994
RefSeq Acc Id: XP_063453763   ⟸   XM_063597693
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063453764   ⟸   XM_063597694
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040364 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057986.1 UniProtKB/TrEMBL
  ENSPPAT00000057991.1 UniProtKB/TrEMBL
  ENSPPAT00000057994.1 UniProtKB/TrEMBL
Gene3D-CATH Amino acid/polyamine transporter I UniProtKB/TrEMBL
InterPro AA/rel_permease1 UniProtKB/TrEMBL
NCBI Gene SLC7A6 ENTREZGENE
PANTHER AMINO ACID TRANSPORTER UniProtKB/TrEMBL
  Y+L AMINO ACID TRANSPORTER 2 UniProtKB/TrEMBL
Pfam AA_permease_2 UniProtKB/TrEMBL
PIRSF AA_transporter UniProtKB/TrEMBL
UniProt A0A2R9BZK3_PANPA UniProtKB/TrEMBL
  A0A2R9C2Q6_PANPA UniProtKB/TrEMBL
  A0A2R9C2R1_PANPA UniProtKB/TrEMBL