CA12 (carbonic anhydrase 12) - Rat Genome Database

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Gene: CA12 (carbonic anhydrase 12) Pan paniscus
Analyze
Symbol: CA12
Name: carbonic anhydrase 12
RGD ID: 11941541
Description: ENCODES a protein that exhibits carbonate dehydratase activity (inferred); lyase activity (inferred); metal ion binding (inferred); INVOLVED IN estrous cycle (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colon adenocarcinoma (ortholog); colorectal adenocarcinoma (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21652,571,690 - 52,630,424 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11556,747,752 - 56,806,529 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01542,270,188 - 42,328,952 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11560,565,592 - 60,624,008 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1560,565,592 - 60,624,008 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CA12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21652,571,690 - 52,630,424 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11556,747,752 - 56,806,529 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01542,270,188 - 42,328,952 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11560,565,592 - 60,624,008 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1560,565,592 - 60,624,008 (-)Ensemblpanpan1.1panPan2
CA12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381563,321,378 - 63,381,846 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1563,321,378 - 63,381,846 (-)EnsemblGRCh38hg38GRCh38
GRCh371563,613,577 - 63,674,045 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361561,402,783 - 61,461,128 (-)NCBINCBI36Build 36hg18NCBI36
Celera1540,494,364 - 40,552,718 (-)NCBICelera
Cytogenetic Map15q22.2NCBI
HuRef1540,438,444 - 40,496,766 (-)NCBIHuRef
CHM1_11563,734,781 - 63,793,114 (-)NCBICHM1_1
T2T-CHM13v2.01561,126,049 - 61,186,532 (-)NCBIT2T-CHM13v2.0
Car12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39966,619,026 - 66,674,127 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl966,620,968 - 66,674,127 (+)EnsemblGRCm39 Ensembl
GRCm38966,712,296 - 66,766,845 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl966,713,686 - 66,766,845 (+)EnsemblGRCm38mm10GRCm38
MGSCv37966,561,493 - 66,614,652 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36966,512,886 - 66,565,989 (+)NCBIMGSCv36mm8
Celera963,948,029 - 64,000,964 (+)NCBICelera
Cytogenetic Map9CNCBI
cM Map936.09NCBI
Car12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8876,169,723 - 76,225,465 (+)NCBIGRCr8
mRatBN7.2867,274,739 - 67,330,428 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl867,274,359 - 67,330,440 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx872,787,939 - 72,840,890 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0871,060,751 - 71,113,710 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0868,930,478 - 68,983,460 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0872,405,770 - 72,461,425 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl872,405,748 - 72,460,240 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0872,071,988 - 72,127,646 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4871,017,732 - 71,070,729 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera866,660,144 - 66,713,076 (+)NCBICelera
Cytogenetic Map8q24NCBI
Ca12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545011,943,340 - 11,975,928 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545011,927,730 - 11,975,553 (+)NCBIChiLan1.0ChiLan1.0
CA12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13027,903,460 - 27,957,162 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3027,905,837 - 27,957,742 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3027,822,431 - 27,876,096 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03028,075,321 - 28,129,041 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3028,077,699 - 28,129,047 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13028,012,749 - 28,066,343 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03028,074,625 - 28,128,260 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03028,311,867 - 28,365,995 (-)NCBIUU_Cfam_GSD_1.0
Ca12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640106,028,826 - 106,081,389 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647123,876,812 - 23,929,987 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647123,876,889 - 23,929,720 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1108,649,271 - 108,710,651 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11108,649,277 - 108,710,658 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21119,822,275 - 119,904,112 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12620,162,706 - 20,221,680 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2620,162,926 - 20,224,502 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048121,178,247 - 121,238,609 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ca12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247819,140,837 - 9,196,400 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247819,140,753 - 9,195,651 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000065097   ⟹   ENSPPAP00000042168
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,565,592 - 60,624,008 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065099   ⟹   ENSPPAP00000042169
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,565,592 - 60,624,008 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065100   ⟹   ENSPPAP00000042170
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,565,592 - 60,623,963 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065101   ⟹   ENSPPAP00000042171
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,568,333 - 60,623,562 (-)Ensembl
RefSeq Acc Id: XM_003827940   ⟹   XP_003827988
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21652,571,690 - 52,630,424 (-)NCBI
NHGRI_mPanPan11556,747,752 - 56,806,529 (-)NCBI
Mhudiblu_PPA_v01542,270,188 - 42,328,952 (-)NCBI
PanPan1.11560,565,592 - 60,624,008 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003827941   ⟹   XP_003827989
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21652,571,690 - 52,630,417 (-)NCBI
NHGRI_mPanPan11556,747,752 - 56,806,524 (-)NCBI
Mhudiblu_PPA_v01542,270,188 - 42,328,948 (-)NCBI
PanPan1.11560,565,592 - 60,624,008 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003827988 (Get FASTA)   NCBI Sequence Viewer  
  XP_003827989 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000042168
  ENSPPAP00000042168.1
  ENSPPAP00000042169
  ENSPPAP00000042169.1
  ENSPPAP00000042170.1
  ENSPPAP00000042171.1
Reference Protein Sequences
RefSeq Acc Id: XP_003827989   ⟸   XM_003827941
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CJN5 (UniProtKB/TrEMBL),   A0A2R9CJN6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003827988   ⟸   XM_003827940
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CMB8 (UniProtKB/TrEMBL),   A0A2R9CJN6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000042169   ⟸   ENSPPAT00000065099
RefSeq Acc Id: ENSPPAP00000042168   ⟸   ENSPPAT00000065097
RefSeq Acc Id: ENSPPAP00000042171   ⟸   ENSPPAT00000065101
RefSeq Acc Id: ENSPPAP00000042170   ⟸   ENSPPAT00000065100
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043661 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000065097.1 UniProtKB/TrEMBL
  ENSPPAT00000065099.1 UniProtKB/TrEMBL
  ENSPPAT00000065100.1 UniProtKB/TrEMBL
  ENSPPAT00000065101.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
KEGG Report pps:100970519 UniProtKB/TrEMBL
NCBI Gene CA12 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF19 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A2R9CJN4_PANPA UniProtKB/TrEMBL
  A0A2R9CJN5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CJN6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CMB8 ENTREZGENE, UniProtKB/TrEMBL