BIRC5 (baculoviral IAP repeat containing 5) - Rat Genome Database

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Gene: BIRC5 (baculoviral IAP repeat containing 5) Pan paniscus
Analyze
Symbol: BIRC5
Name: baculoviral IAP repeat containing 5
RGD ID: 11938488
Description: ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity involved in apoptotic process (ortholog); enzyme binding (ortholog); identical protein binding (ortholog); INVOLVED IN cell division (ortholog); cellular response to ethanol (ortholog); cellular response to stem cell factor stimulus (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH acute megakaryocytic leukemia (ortholog); acute necrotizing pancreatitis (ortholog); acute pancreatitis (ortholog); FOUND IN apical plasma membrane (ortholog); centriole (ortholog); chromosome passenger complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: baculoviral IAP repeat-containing protein 5
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21994,265,019 - 94,276,237 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11799,094,471 - 99,105,679 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01772,292,332 - 72,303,493 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11777,842,724 - 77,854,159 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1777,842,724 - 77,854,159 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute megakaryocytic leukemia  (ISO)
acute necrotizing pancreatitis  (ISO)
acute pancreatitis  (ISO)
acute promyelocytic leukemia  (ISO)
adenocarcinoma  (ISO)
adrenocortical carcinoma  (ISO)
adult T-cell leukemia/lymphoma  (ISO)
bladder urothelial carcinoma  (ISO)
brain glioma  (ISO)
Brain Injuries  (ISO)
breast carcinoma  (ISO)
Breast Neoplasms  (ISO)
chromophobe renal cell carcinoma  (ISO)
chronic myeloid leukemia  (ISO)
clear cell renal cell carcinoma  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
COVID-19  (ISO)
ductal carcinoma in situ  (ISO)
endometrial hyperplasia  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Liver Neoplasms  (ISO)
genetic disease  (ISO)
Germ Cell and Embryonal Neoplasms  (ISO)
hepatocellular carcinoma  (ISO)
high grade glioma  (ISO)
Kidney Neoplasms  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
malignant pleural mesothelioma  (ISO)
Mesothelioma  (ISO)
myocardial infarction  (ISO)
oral squamous cell carcinoma  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic adenocarcinoma  (ISO)
papillary renal cell carcinoma  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary hypertension  (ISO)
Refractory Anemia  (ISO)
Refractory Anemia with Excess of Blasts  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
small cell carcinoma  (ISO)
squamous cell carcinoma  (ISO)
stomach carcinoma  (ISO)
Stomach Neoplasms  (ISO)
Testicular Germ Cell Tumor  (ISO)
thymoma  (ISO)
thyroid gland carcinoma  (ISO)
transitional cell carcinoma  (ISO)
urinary bladder cancer  (ISO)
Urologic Neoplasms  (ISO)
Uterine Cervical Neoplasms  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
BIRC5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21994,265,019 - 94,276,237 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11799,094,471 - 99,105,679 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01772,292,332 - 72,303,493 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11777,842,724 - 77,854,159 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1777,842,724 - 77,854,159 (+)Ensemblpanpan1.1panPan2
BIRC5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381778,214,253 - 78,225,635 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1778,214,186 - 78,225,636 (+)EnsemblGRCh38hg38GRCh38
GRCh371776,210,334 - 76,221,716 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361773,721,872 - 73,733,311 (+)NCBINCBI36Build 36hg18NCBI36
Build 341773,721,871 - 73,733,310NCBI
Celera1772,806,306 - 72,817,744 (+)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1771,634,433 - 71,645,847 (+)NCBIHuRef
CHM1_11776,274,801 - 76,286,240 (+)NCBICHM1_1
T2T-CHM13v2.01779,108,345 - 79,119,727 (+)NCBIT2T-CHM13v2.0
Birc5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911117,740,063 - 117,746,569 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11117,740,077 - 117,746,569 (+)EnsemblGRCm39 Ensembl
GRCm3811117,849,237 - 117,855,743 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11117,849,251 - 117,855,743 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711117,710,551 - 117,717,057 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611117,665,327 - 117,671,833 (+)NCBIMGSCv36mm8
Celera11129,594,259 - 129,600,765 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1182.96NCBI
Birc5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810103,567,369 - 103,580,069 (+)NCBIGRCr8
mRatBN7.210103,072,530 - 103,081,382 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10103,073,408 - 103,081,380 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10108,174,435 - 108,182,841 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010107,637,549 - 107,645,954 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010102,994,242 - 103,002,165 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010106,856,097 - 106,864,419 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10106,856,097 - 106,864,413 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010106,494,775 - 106,503,097 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10101,633,441 - 101,641,341 (+)NCBICelera
Cytogenetic Map10q32.2NCBI
BIRC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.192,930,308 - 2,959,307 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha93,613,921 - 3,619,074 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.093,608,303 - 3,613,418 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.193,631,386 - 3,636,494 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.093,755,584 - 3,761,556 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.093,836,949 - 3,842,103 (-)NCBIUU_Cfam_GSD_1.0
Birc5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056023,591,620 - 3,599,727 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365942,812,238 - 2,820,636 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365942,812,165 - 2,820,618 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BIRC5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl123,747,279 - 3,755,215 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1123,747,276 - 3,755,214 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
BIRC5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11670,226,824 - 70,237,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607741,335,707 - 41,347,619 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Birc5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248017,727,093 - 7,735,940 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248017,727,084 - 7,735,946 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000041238   ⟹   ENSPPAP00000018506
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1777,842,724 - 77,854,159 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000041243   ⟹   ENSPPAP00000018511
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1777,842,724 - 77,854,159 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000041267   ⟹   ENSPPAP00000018535
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1777,842,844 - 77,852,330 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000041270   ⟹   ENSPPAP00000018538
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1777,842,844 - 77,851,638 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000041274   ⟹   ENSPPAP00000018542
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1777,842,844 - 77,849,830 (+)Ensembl
RefSeq Acc Id: XM_003818274   ⟹   XP_003818322
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21994,265,019 - 94,276,237 (+)NCBI
NHGRI_mPanPan11799,094,471 - 99,105,679 (+)NCBI
Mhudiblu_PPA_v01772,292,339 - 72,303,493 (+)NCBI
PanPan1.11777,842,724 - 77,854,159 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008971542   ⟹   XP_008969790
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21994,265,039 - 94,276,237 (+)NCBI
NHGRI_mPanPan11799,094,491 - 99,105,679 (+)NCBI
Mhudiblu_PPA_v01772,292,332 - 72,303,493 (+)NCBI
PanPan1.11777,842,724 - 77,854,159 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003818322   ⟸   XM_003818274
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AMD6 (UniProtKB/TrEMBL),   A0A2R9ARZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008969790   ⟸   XM_008971542
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AME1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000018535   ⟸   ENSPPAT00000041267
RefSeq Acc Id: ENSPPAP00000018538   ⟸   ENSPPAT00000041270
RefSeq Acc Id: ENSPPAP00000018542   ⟸   ENSPPAT00000041274
RefSeq Acc Id: ENSPPAP00000018506   ⟸   ENSPPAT00000041238
RefSeq Acc Id: ENSPPAP00000018511   ⟸   ENSPPAT00000041243


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032377 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041238.1 UniProtKB/TrEMBL
  ENSPPAT00000041243.1 UniProtKB/TrEMBL
  ENSPPAT00000041267.1 UniProtKB/TrEMBL
  ENSPPAT00000041270.1 UniProtKB/TrEMBL
  ENSPPAT00000041274.1 UniProtKB/TrEMBL
InterPro BIR_rpt UniProtKB/TrEMBL
KEGG Report pps:100980532 UniProtKB/TrEMBL
NCBI Gene BIRC5 ENTREZGENE
PANTHER BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5 UniProtKB/TrEMBL
  DETERIN UniProtKB/TrEMBL
Pfam BIR UniProtKB/TrEMBL
PROSITE BIR_REPEAT_2 UniProtKB/TrEMBL
SMART BIR UniProtKB/TrEMBL
Superfamily-SCOP Inhibitor of apoptosis (IAP) repeat UniProtKB/TrEMBL
UniProt A0A2R9AMD6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AME1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AMF8_PANPA UniProtKB/TrEMBL
  A0A2R9AN13_PANPA UniProtKB/TrEMBL
  A0A2R9ARZ3 ENTREZGENE, UniProtKB/TrEMBL