OLAH (oleoyl-ACP hydrolase) - Rat Genome Database

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Gene: OLAH (oleoyl-ACP hydrolase) Pan paniscus
Analyze
Symbol: OLAH
Name: oleoyl-ACP hydrolase
RGD ID: 11938174
Description: ENCODES a protein that exhibits fatty acyl-[ACP] hydrolase activity (inferred); INVOLVED IN biosynthetic process (inferred); fatty acid biosynthetic process (inferred); fatty acid metabolic process (inferred); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: S-acyl fatty acid synthase thioesterase, medium chain
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,871,899 - 27,913,162 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,863,914 - 27,918,488 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01015,356,380 - 15,386,599 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11015,642,307 - 15,667,461 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1015,642,307 - 15,667,461 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
OLAH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,871,899 - 27,913,162 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,863,914 - 27,918,488 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01015,356,380 - 15,386,599 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11015,642,307 - 15,667,461 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1015,642,307 - 15,667,461 (+)Ensemblpanpan1.1panPan2
OLAH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381015,032,195 - 15,073,853 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1015,032,227 - 15,073,853 (+)EnsemblGRCh38hg38GRCh38
GRCh371015,085,942 - 15,115,852 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361015,125,951 - 15,155,857 (+)NCBINCBI36Build 36hg18NCBI36
Build 341015,125,967 - 15,155,857NCBI
Celera1015,014,547 - 15,044,484 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1014,996,532 - 15,026,428 (+)NCBIHuRef
CHM1_11015,086,018 - 15,115,972 (+)NCBICHM1_1
T2T-CHM13v2.01015,046,189 - 15,087,828 (+)NCBIT2T-CHM13v2.0
Olah
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3923,343,019 - 3,367,964 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl23,343,019 - 3,398,247 (-)EnsemblGRCm39 Ensembl
GRCm3823,341,987 - 3,366,569 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl23,341,982 - 3,397,210 (-)EnsemblGRCm38mm10GRCm38
MGSCv3723,259,259 - 3,283,841 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3623,259,259 - 3,283,841 (-)NCBIMGSCv36mm8
Celera23,293,581 - 3,318,824 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map21.88NCBI
Olah
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,786,441 - 79,811,692 (+)NCBIGRCr8
mRatBN7.21774,877,651 - 74,902,517 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,877,655 - 74,902,518 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1778,344,154 - 78,369,062 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,179,537 - 82,204,441 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,227,488 - 76,252,386 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,878,673 - 78,903,919 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,879,058 - 78,903,967 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01780,520,857 - 80,545,540 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41785,996,338 - 86,021,192 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11786,007,173 - 86,032,019 (+)NCBI
Celera1774,257,064 - 74,281,908 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
Olah
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542919,376,190 - 19,394,119 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542919,375,366 - 19,394,068 (-)NCBIChiLan1.0ChiLan1.0
Olah
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093446,954,560 - 7,020,324 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366131,541,001 - 1,570,882 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OLAH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,752,243 - 46,771,986 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11046,752,241 - 46,770,881 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,485,496 - 51,511,675 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OLAH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1915,028,667 - 15,048,611 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl915,032,574 - 15,048,568 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605120,576,767 - 20,590,550 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Olah
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624805476,612 - 495,158 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624805476,106 - 494,612 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000062277   ⟹   ENSPPAP00000039367
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1015,642,307 - 15,667,461 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000062279   ⟹   ENSPPAP00000039369
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1015,642,307 - 15,667,461 (+)Ensembl
RefSeq Acc Id: XM_063607198   ⟹   XP_063463268
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2827,871,899 - 27,913,162 (+)NCBI
Protein Sequences
Protein RefSeqs XP_063463268 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000039367.1
  ENSPPAP00000039369.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000039367   ⟸   ENSPPAT00000062277
RefSeq Acc Id: ENSPPAP00000039369   ⟸   ENSPPAT00000062279
RefSeq Acc Id: XP_063463268   ⟸   XM_063607198
Protein Domains
Thioesterase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042386 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062277.1 UniProtKB/TrEMBL
  ENSPPAT00000062279.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  TEII UniProtKB/TrEMBL
  Thioesterase UniProtKB/TrEMBL
NCBI Gene OLAH ENTREZGENE
PANTHER PTHR11487 UniProtKB/TrEMBL
  S-ACYL FATTY ACID SYNTHASE THIOESTERASE, MEDIUM CHAIN UniProtKB/TrEMBL
Pfam Thioesterase UniProtKB/TrEMBL
PRINTS F138DOMAIN UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A2R9CBW4_PANPA UniProtKB/TrEMBL
  A0A2R9CMN6_PANPA UniProtKB/TrEMBL