ATP6V1B1 (ATPase H+ transporting V1 subunit B1)

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Gene: ATP6V1B1 (ATPase H+ transporting V1 subunit B1) Pan paniscus

Analyze

Symbol:

ATP6V1B1

Name:

ATPase H+ transporting V1 subunit B1

RGD ID:

11936342

Description:

ENCODES a protein that exhibits protein-containing complex binding (ortholog); proton transmembrane transporter activity (ortholog); INVOLVED IN adult behavior (ortholog); ATP metabolic process (ortholog); calcium ion homeostasis (ortholog); ASSOCIATED WITH Distal Renal Tubular Acidosis 2 with Progressive Nerve Deafness (ortholog); genetic disease (ortholog); nephrocalcinosis (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

V-type proton ATPase subunit B, kidney isoform

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	72,113,863 - 72,143,524 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	72,113,859 - 72,143,612 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2A	71,000,096 - 71,030,306 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Distal Renal Tubular Acidosis 2 with Progressive Nerve Deafness (ISO)

genetic disease (ISO)

nephrocalcinosis (ISO)

Postaxial Polydactyly, Type A1 (ISO)

renal tubular acidosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult behavior (ISO)

ATP metabolic process (ISO)

calcium ion homeostasis (ISO)

chloride ion homeostasis (ISO)

excretion (ISO)

inner ear morphogenesis (ISO)

olfactory behavior (ISO)

ossification (ISO)

pH reduction (ISO)

potassium ion homeostasis (ISO)

prostaglandin metabolic process (ISO)

proton transmembrane transport (ISO)

regulation of gene expression (ISO)

regulation of pH (ISO)

renal sodium excretion (ISO)

renal sodium ion transport (ISO)

renal water homeostasis (ISO)

sensory perception of sound (ISO)

Cellular Component

apical plasma membrane (ISO)

basolateral plasma membrane (ISO)

cytoplasm (ISO)

cytosol (ISO)

extrinsic component of synaptic vesicle membrane (ISO)

lateral plasma membrane (ISO)

membrane (ISO)

microvillus (ISO)

synaptic vesicle (ISO)

vacuolar proton-transporting V-type ATPase complex (ISO)

Molecular Function

protein binding (ISO)

protein-containing complex binding (ISO)

proton transmembrane transporter activity (ISO)

References

Genomics

Comparative Map Data

ATP6V1B1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	72,113,863 - 72,143,524 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	72,113,859 - 72,143,612 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2A	71,000,096 - 71,030,306 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

ATP6V1B1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	70,935,900 - 70,965,431 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	70,935,900 - 70,965,431 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	71,163,030 - 71,192,561 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	71,016,506 - 71,046,069 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	71,074,674 - 71,104,207	NCBI
Celera	2	71,013,684 - 71,043,243 (+)	NCBI
Cytogenetic Map	2	p13.3	NCBI
HuRef	2	70,899,497 - 70,928,997 (+)	NCBI		HuRef
CHM1_1	2	71,092,347 - 71,121,872 (+)	NCBI		CHM1_1

Atp6v1b1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	83,719,999 - 83,735,837 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	83,719,972 - 83,735,837 (+)	Ensembl
GRCm38	6	83,743,017 - 83,758,855 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	83,742,990 - 83,758,855 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	83,693,011 - 83,708,804 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	83,708,675 - 83,724,468 (+)	NCBI			mm8
Celera	6	85,725,645 - 85,742,032 (+)	NCBI		Celera
Cytogenetic Map	6	C3	NCBI
cM Map	6	35.94	NCBI

Atp6v1b1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	116,223,799 - 116,242,475 (+)	NCBI
Rnor_6.0 Ensembl	4	115,416,580 - 115,437,206 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	4	115,417,100 - 115,435,754 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	4	180,004,952 - 180,024,878 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	117,931,972 - 117,950,626 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	118,176,425 - 118,194,509 (+)	NCBI
Celera	4	105,216,251 - 105,234,921 (+)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

Atp6v1b1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	14,256,096 - 14,282,410 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	14,256,096 - 14,281,572 (-)	NCBI	ChiLan1.0	ChiLan1.0

ATP6V1B1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	10	69,252,926 - 69,287,542 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	10	69,261,311 - 69,287,540 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Atp6v1b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936491	15,112,422 - 15,138,716 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATP6V1B1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	71,560,738 - 71,591,856 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	71,560,102 - 71,591,885 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	75,019,974 - 75,027,732 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATP6V1B1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	36,149,074 - 36,179,145 (-)	NCBI
ChlSab1.1 Ensembl	14	36,149,006 - 36,177,671 (-)	Ensembl

Atp6v1b1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624762	2,445,840 - 2,480,377 (-)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003830953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	SSBP01000201	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSPPAT00000028947 ⟹ ENSPPAP00000006998

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2A	72,113,859 - 72,143,612 (+)	Ensembl

RefSeq Acc Id:

XM_003830953 ⟹ XP_003831001

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1	2A	72,113,863 - 72,143,524 (+)	NCBI
Mhudiblu_PPA_v0	2A	71,000,096 - 71,030,306 (+)	NCBI

Sequence:

show sequence

CTGAGCGGCTCTCTCCAGCTCCAGCTGGACCTGAAGTCTCAGAGCTGCCACCAGCAGTAGCCTC
GGACACTGGGCTCCCAGCTGGGCACTGCTCCATGGCCATGGAGATAGACAGCAGGCCTGGGGGG
CTCCCCGGCAGTGGCTGCAACCTAGGTGCAGCCCGAGAACACATGCAGGCGGTCACCCGAAACT
ACATCACCCACCCCCGTGTCACCTACAGGACTGTGTGCAGCGTGAACGGGCCCCTGGTGGTGCT
GGACCGGGTCAAGTTTGCCCAGTATGCGGAGATCGTCCACTTCACCCTCCCAGATGGGACTCAG
AGGAGCGGGCAGGTGCTTGAGGTGGCTGGCACCAAGGCGATTGTTCAGGTGTTTGAAGGGACAT
CAGGGATCGATGCCAGGAAGACCACTTGCGAATTTACAGGGGACATCCTACGAACTCCGGTGTC
AGAGGACATGCTGGGTCGGGTTTTCAATGGCTCCGGCAAGCCCATTGACAAGGGGCCAGTGGTC
ATGGCGGAGGACTTTCTGGATATCAATGGCCAGCCCATCAACCCGCACTCCCGCATCTACCCCG
AGGAGATGATTCAGACGGGCATTTCTCCTATTGACGTCATGAACAGCATTGCCCGTGGCCAGAA
GATCCCCATCTTCTCAGCAGCCGGGCTCCCCCACAATGAGATTGCCGCTCAGATCTGCCGCCAG
GCGGGGCTGGTGAAGAAGTCCAAGGCTGTGCTGGATTACCATGACGACAACTTCGCCATCGTCT
TTGCAGCCATGGGGGTGAACATGGAGACAGCCAGATTCTTCAAGTCTGACTTTGAGCAGAATGG
AACCATGGGGAACGTCTGCCTCTTCCTGAACTTGGCCAATGACCCCACGATCGAGCGGATCATC
ACCCCGCGCCTGGCGCTGACCACTGCTGAATTCCTTGCCTACCAGTGTGAGAAGCATGTGCTGG
TCATACTGACGGACATGAGTTCCTATGCAGAGGCCTTGCGGGAGGTCTCTGCTGCTAGAGAAGA
GGTGCCTGGGCGCCGAGGGTTTCCTGGATATATGTACACAGACCTGGCCACCATCTACGAGCGG
GCAGGCCGCGTGGAGGGTCGGGGAGGATCCATCACACAGATCCCCATCCTCACCATGCCCAACG
ACGATATCACCCACCCTATCCCAGACTTGACGGGCTTCATCACAGAGGGACAGATCTACGTGGA
CAGACAGCTTCACAACAGACAGATCTACCCCCCCATCAACGTGCTCCCTTCCCTGTCGCGGCTG
ATGAAGTCAGCCATTGGGGAAGGCATGACAAGAAAGGACCATGGAGATGTCTCCAACCAGCTGT
ACGCCTGCTATGCCATCGGGAAGGACGTGCAGGCCATGAAGGCAGTAGTTGGGGAGGAGGCGCT
CACCTCTGAGGACCTGCTCTACCTGGAATTTCTGCAGAAGTTTGAGAAGAACTTCATCAATCAG
GGCCCCTACGAGAACCGCTCGGTGTTCGAGTCGCTGGACCTGGGCTGGAAGCTGCTGCGCATCT
TCCCCAAGGAGATGCTGAAGCGCATTCCGCAGGCCGTGATCGACGAGTTCTATTCCCGCGAGGG
GGCGCTGCAGGACCTCGCGCCTGACACGGCGCTCTAGCCCCGCGCGCCGTGGCACCCCAACACC
GGCAGGGAACCTACCCTCGGCTCCCGGGTCTCCCCTCCCTCGCCACCCCAACCAGCGGCTTCTG
CGCCGCCCTCCGCCCTCCGCTGGCTCCGAGGTGGTGGGGGCGCCGCACGCTCCATCCCTTTCCC
TCGCTCGATTCCTTTTCCCGCGCTCCATGCCTCCCCCTCGACTCCCGGTGCTGCGGAAGAACCG
AAGGTTGCGATGCCTTACTCTGACGGGAGCATCTGTATTTTTATGTTAAAAGCCCACAAAATAA
AAATAAAAAGTAACTGAGATGAATTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003831001	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_003831001 ⟸ XM_003830953

- Sequence:

show sequence

MAMEIDSRPGGLPGSGCNLGAAREHMQAVTRNYITHPRVTYRTVCSVNGPLVVLDRVKFAQYAE
IVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRVFNG
SGKPIDKGPVVMAEDFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLP
HNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLN
LANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGY
MYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYP
PINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEF
LQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSREGALQDLAPDTA
L

hide sequence

RefSeq Acc Id:

ENSPPAP00000006998 ⟸ ENSPPAT00000028947

Protein Domains

ATP-synt_ab ATP-synt_ab_N

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000026048	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSPPAP00000006998	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000028947	UniProtKB/TrEMBL
InterPro	ATPase_a/bsu_AS	UniProtKB/TrEMBL
	ATPase_F1/V1/A1_a/bsu_N	UniProtKB/TrEMBL
	ATPase_F1/V1/A1_a/bsu_nucl-bd	UniProtKB/TrEMBL
	ATPase_V1-cplx_bsu	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	V-ATPase_su_B/beta	UniProtKB/TrEMBL
KEGG Report	pps:100976103	UniProtKB/TrEMBL
NCBI Gene	ATP6V1B1	ENTREZGENE
PANTHER	PTHR43389	UniProtKB/TrEMBL
Pfam	ATP-synt_ab	UniProtKB/TrEMBL
	ATP-synt_ab_N	UniProtKB/TrEMBL
PIRSF	V-ATPsynth_beta/V-ATPase_B	UniProtKB/TrEMBL
PROSITE	ATPASE_ALPHA_BETA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
TIGRFAMs	V-ATPase_V1_B	UniProtKB/TrEMBL
UniProt	A0A2R8ZSZ1_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM