IGF2BP1 (insulin like growth factor 2 mRNA binding protein 1) - Rat Genome Database

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Gene: IGF2BP1 (insulin like growth factor 2 mRNA binding protein 1) Pan paniscus
Analyze
Symbol: IGF2BP1
Name: insulin like growth factor 2 mRNA binding protein 1
RGD ID: 11932628
Description: ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); INVOLVED IN dendrite arborization (ortholog); neuronal stem cell population maintenance (ortholog); pallium cell proliferation in forebrain (ortholog); ASSOCIATED WITH colon adenoma (ortholog); Experimental Neoplasms (ortholog); genetic disease (ortholog); FOUND IN axon (ortholog); CRD-mediated mRNA stability complex (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: insulin-like growth factor 2 mRNA-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21916,042,863 - 16,101,303 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11718,008,913 - 18,067,542 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0178,479,806 - 8,538,336 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1178,461,552 - 8,519,550 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl178,468,240 - 8,519,552 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
IGF2BP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21916,042,863 - 16,101,303 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11718,008,913 - 18,067,542 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0178,479,806 - 8,538,336 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1178,461,552 - 8,519,550 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl178,468,240 - 8,519,552 (-)Ensemblpanpan1.1panPan2
IGF2BP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381748,996,558 - 49,056,145 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1748,997,385 - 49,056,145 (+)EnsemblGRCh38hg38GRCh38
GRCh371747,074,747 - 47,133,507 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361744,429,773 - 44,488,506 (+)NCBINCBI36Build 36hg18NCBI36
Celera1743,529,020 - 43,588,502 (+)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1742,441,949 - 42,500,581 (+)NCBIHuRef
CHM1_11747,140,077 - 47,198,718 (+)NCBICHM1_1
T2T-CHM13v2.01749,859,908 - 49,919,501 (+)NCBIT2T-CHM13v2.0
Igf2bp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391195,847,989 - 95,896,770 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1195,847,989 - 95,896,766 (-)EnsemblGRCm39 Ensembl
GRCm381195,957,163 - 96,005,944 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1195,957,163 - 96,005,940 (-)EnsemblGRCm38mm10GRCm38
MGSCv371195,818,477 - 95,867,258 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361195,778,822 - 95,822,002 (-)NCBIMGSCv36mm8
Celera11105,607,858 - 105,656,580 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.08NCBI
Igf2bp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81081,405,021 - 81,447,814 (-)NCBIGRCr8
mRatBN7.21080,908,300 - 80,951,097 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1080,908,076 - 80,951,129 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1085,857,301 - 85,899,408 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01085,355,335 - 85,397,441 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01080,747,478 - 80,789,863 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01083,774,178 - 83,823,323 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1083,780,203 - 83,822,996 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01083,579,028 - 83,628,914 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41084,671,084 - 84,714,648 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11084,685,453 - 84,729,018 (-)NCBI
Celera1079,676,729 - 79,719,122 (-)NCBICelera
Cytogenetic Map10q26NCBI
Igf2bp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545112,312,715 - 12,348,663 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545112,312,715 - 12,348,663 (-)NCBIChiLan1.0ChiLan1.0
IGF2BP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1925,199,287 - 25,240,693 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl925,198,805 - 25,240,578 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha924,660,181 - 24,703,349 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0925,994,308 - 26,036,588 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl925,993,861 - 26,034,618 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1924,762,182 - 24,805,339 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0925,020,613 - 25,063,780 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0925,149,583 - 25,192,753 (+)NCBIUU_Cfam_GSD_1.0
Igf2bp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560224,605,834 - 24,645,145 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649012,430,008 - 12,469,083 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649012,430,343 - 12,468,794 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGF2BP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1225,197,058 - 25,243,272 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11225,196,955 - 25,244,660 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21225,162,754 - 25,209,240 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IGF2BP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11669,405,923 - 69,461,613 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1669,406,549 - 69,459,175 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607740,510,372 - 40,569,936 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igf2bp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247955,353,005 - 5,385,521 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247955,352,932 - 5,391,617 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000057724   ⟹   ENSPPAP00000034839
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl178,468,240 - 8,519,552 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057730   ⟹   ENSPPAP00000034845
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl178,468,240 - 8,519,018 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057732   ⟹   ENSPPAP00000034847
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl178,468,240 - 8,519,018 (-)Ensembl
RefSeq Acc Id: XM_008962402   ⟹   XP_008960650
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21916,042,863 - 16,101,303 (-)NCBI
NHGRI_mPanPan11718,008,913 - 18,067,252 (-)NCBI
Mhudiblu_PPA_v0178,479,806 - 8,538,045 (-)NCBI
PanPan1.1178,461,552 - 8,519,550 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063598951   ⟹   XP_063455021
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21916,042,863 - 16,101,302 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008960650 (Get FASTA)   NCBI Sequence Viewer  
  XP_063455021 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034839.1
  ENSPPAP00000034845.1
  ENSPPAP00000034847.1
RefSeq Acc Id: XP_008960650   ⟸   XM_008962402
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C228 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000034839   ⟸   ENSPPAT00000057724
RefSeq Acc Id: ENSPPAP00000034847   ⟸   ENSPPAT00000057732
RefSeq Acc Id: ENSPPAP00000034845   ⟸   ENSPPAT00000057730
RefSeq Acc Id: XP_063455021   ⟸   XM_063598951
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C8U3 (UniProtKB/TrEMBL)
Protein Domains
RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040224 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057724.1 UniProtKB/TrEMBL
  ENSPPAT00000057730.1 UniProtKB/TrEMBL
  ENSPPAT00000057732.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
  3.30.310.210 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro IGF2BP1_RRM1 UniProtKB/TrEMBL
  KH_dom UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
KEGG Report pps:100992598 UniProtKB/TrEMBL
NCBI Gene IGF2BP1 ENTREZGENE
PANTHER INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 1 UniProtKB/TrEMBL
  KH DOMAIN CONTAINING RNA BINDING PROTEIN UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PROSITE KH_TYPE_1 UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
  SM00322 UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A2R9BYU8_PANPA UniProtKB/TrEMBL
  A0A2R9C228 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C8U3 ENTREZGENE, UniProtKB/TrEMBL