PLEKHA1 (pleckstrin homology domain containing A1) - Rat Genome Database

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Gene: PLEKHA1 (pleckstrin homology domain containing A1) Pan paniscus
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Symbol: PLEKHA1
Name: pleckstrin homology domain containing A1
RGD ID: 11928284
Description: ENCODES a protein that exhibits PDZ domain binding (inferred); phosphatidylinositol-3,4-bisphosphate binding (inferred); INVOLVED IN androgen metabolic process (ortholog); estrogen metabolic process (ortholog); face morphogenesis (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH COVID-19 (ortholog); craniosynostosis (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain-containing family A member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28134,230,044 - 134,287,769 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110134,235,565 - 134,293,121 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010118,942,896 - 119,001,185 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110122,354,773 - 122,412,588 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10122,354,765 - 122,412,588 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
PLEKHA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28134,230,044 - 134,287,769 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110134,235,565 - 134,293,121 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010118,942,896 - 119,001,185 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110122,354,773 - 122,412,588 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10122,354,765 - 122,412,588 (+)Ensemblpanpan1.1panPan2
PLEKHA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810122,374,708 - 122,442,600 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10122,374,696 - 122,432,354 (+)EnsemblGRCh38hg38GRCh38
GRCh3710124,134,224 - 124,202,116 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610124,124,210 - 124,181,856 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410124,141,832 - 124,181,856NCBI
Celera10117,866,583 - 117,924,124 (+)NCBICelera
Cytogenetic Map10q26.13NCBI
HuRef10117,764,924 - 117,822,671 (+)NCBIHuRef
CHM1_110124,418,717 - 124,476,463 (+)NCBICHM1_1
T2T-CHM13v2.010123,270,978 - 123,338,841 (+)NCBIT2T-CHM13v2.0
Plekha1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397130,462,281 - 130,515,224 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7130,467,486 - 130,515,042 (+)EnsemblGRCm39 Ensembl
GRCm387130,860,551 - 130,913,494 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7130,865,756 - 130,913,312 (+)EnsemblGRCm38mm10GRCm38
MGSCv377138,009,424 - 138,056,816 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367130,657,058 - 130,704,450 (+)NCBIMGSCv36mm8
Celera7130,676,697 - 130,724,178 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map773.19NCBI
Plekha1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,858,239 - 194,909,418 (+)NCBIGRCr8
mRatBN7.21185,427,982 - 185,479,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1185,428,048 - 185,479,156 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1193,778,280 - 193,829,384 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01200,956,894 - 201,007,940 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01193,628,667 - 193,679,713 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01201,429,716 - 201,481,411 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1201,429,771 - 201,480,877 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01208,462,186 - 208,513,824 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41190,187,202 - 190,238,309 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1183,040,481 - 183,091,589 (+)NCBICelera
Cytogenetic Map1q41NCBI
Plekha1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955477659,641 - 732,627 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955477659,640 - 730,394 (+)NCBIChiLan1.0ChiLan1.0
PLEKHA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12832,025,791 - 32,081,824 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2832,026,350 - 32,081,835 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2832,100,800 - 32,156,873 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02832,561,443 - 32,617,733 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2832,561,576 - 32,617,733 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12832,093,840 - 32,149,960 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02832,115,324 - 32,171,582 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02832,319,773 - 32,376,120 (+)NCBIUU_Cfam_GSD_1.0
Plekha1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721314,322,684 - 14,377,443 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648611,203,873 - 11,241,028 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14131,960,939 - 132,016,652 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114131,960,932 - 132,016,664 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214143,414,765 - 143,470,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19115,110,316 - 115,168,113 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9115,128,942 - 115,165,576 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604876,408,461 - 76,466,336 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekha1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473724,299,199 - 24,365,459 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000004845   ⟹   ENSPPAP00000001044
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10122,354,765 - 122,412,588 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000004950   ⟹   ENSPPAP00000001062
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10122,354,771 - 122,412,588 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000005018   ⟹   ENSPPAP00000001074
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10122,373,485 - 122,410,169 (+)Ensembl
RefSeq Acc Id: XM_003825668   ⟹   XP_003825716
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,213 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,235,565 - 134,293,121 (+)NCBI
Mhudiblu_PPA_v010118,943,505 - 119,001,185 (+)NCBI
PanPan1.110122,354,783 - 122,412,588 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951011   ⟹   XP_008949259
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,682 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,236,041 - 134,293,121 (+)NCBI
Mhudiblu_PPA_v010118,944,374 - 119,001,185 (+)NCBI
PanPan1.110122,355,632 - 122,412,588 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951012   ⟹   XP_008949260
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,689 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,236,041 - 134,293,121 (+)NCBI
Mhudiblu_PPA_v010118,944,367 - 119,001,185 (+)NCBI
PanPan1.110122,355,693 - 122,412,588 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951013   ⟹   XP_008949261
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,169 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,235,565 - 134,293,121 (+)NCBI
Mhudiblu_PPA_v010118,942,920 - 119,001,185 (+)NCBI
PanPan1.110122,354,777 - 122,412,588 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951014   ⟹   XP_008949262
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,044 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,235,565 - 134,293,121 (+)NCBI
Mhudiblu_PPA_v010118,942,925 - 119,001,185 (+)NCBI
PanPan1.110122,354,779 - 122,412,588 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014346568   ⟹   XP_014202054
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,371 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,235,723 - 134,293,121 (+)NCBI
Mhudiblu_PPA_v010118,943,768 - 119,001,185 (+)NCBI
PanPan1.110122,355,136 - 122,412,588 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034931634   ⟹   XP_034787525
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,248,703 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,254,055 - 134,293,121 (+)NCBI
Mhudiblu_PPA_v010118,962,112 - 119,001,185 (+)NCBI
RefSeq Acc Id: XM_055093417   ⟹   XP_054949392
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,689 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,236,041 - 134,293,121 (+)NCBI
RefSeq Acc Id: XM_055093419   ⟹   XP_054949394
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,689 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,236,041 - 134,293,121 (+)NCBI
RefSeq Acc Id: XM_055093420   ⟹   XP_054949395
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,679 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,236,041 - 134,293,121 (+)NCBI
RefSeq Acc Id: XM_055093421   ⟹   XP_054949396
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,682 - 134,287,769 (+)NCBI
NHGRI_mPanPan110134,236,035 - 134,293,121 (+)NCBI
RefSeq Acc Id: XM_063607545   ⟹   XP_063463615
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,371 - 134,287,769 (+)NCBI
RefSeq Acc Id: XM_063607546   ⟹   XP_063463616
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28134,230,371 - 134,287,769 (+)NCBI
RefSeq Acc Id: XP_008949261   ⟸   XM_008951013
- Peptide Label: isoform X2
- UniProtKB: A0A2R8Z893 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949262   ⟸   XM_008951014
- Peptide Label: isoform X3
- UniProtKB: A0A2R8Z893 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003825716   ⟸   XM_003825668
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Z841 (UniProtKB/TrEMBL),   A0A2R8Z8B9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_014202054   ⟸   XM_014346568
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Z841 (UniProtKB/TrEMBL),   A0A2R8Z8B9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949259   ⟸   XM_008951011
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Z841 (UniProtKB/TrEMBL),   A0A2R8Z8B9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949260   ⟸   XM_008951012
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Z841 (UniProtKB/TrEMBL),   A0A2R8Z8B9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034787525   ⟸   XM_034931634
- Peptide Label: isoform X4
- UniProtKB: A0A2R8Z8B9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000001074   ⟸   ENSPPAT00000005018
RefSeq Acc Id: ENSPPAP00000001044   ⟸   ENSPPAT00000004845
RefSeq Acc Id: ENSPPAP00000001062   ⟸   ENSPPAT00000004950
RefSeq Acc Id: XP_054949396   ⟸   XM_055093421
- Peptide Label: isoform X3
- UniProtKB: A0A2R8Z893 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054949392   ⟸   XM_055093417
- Peptide Label: isoform X2
- UniProtKB: A0A2R8Z893 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054949394   ⟸   XM_055093419
- Peptide Label: isoform X2
- UniProtKB: A0A2R8Z893 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054949395   ⟸   XM_055093420
- Peptide Label: isoform X3
- UniProtKB: A0A2R8Z893 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063463615   ⟸   XM_063607545
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063463616   ⟸   XM_063607546
- Peptide Label: isoform X3
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000003709 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000004845.1 UniProtKB/TrEMBL
  ENSPPAT00000004950.1 UniProtKB/TrEMBL
  ENSPPAT00000005018.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report pps:100984380 UniProtKB/TrEMBL
NCBI Gene PLEKHA1 ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 1 UniProtKB/TrEMBL
  TANDEM PH DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A2R8Z841 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8Z893 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8Z8B9 ENTREZGENE, UniProtKB/TrEMBL