SLIT3 (slit guidance ligand 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: SLIT3 (slit guidance ligand 3) Pan paniscus
Analyze
Symbol: SLIT3
Name: slit guidance ligand 3
RGD ID: 11924499
Description: ENCODES a protein that exhibits calcium ion binding (inferred); heparin binding (inferred); Roundabout binding (inferred); INVOLVED IN animal organ morphogenesis (ortholog); axon guidance (ortholog); chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); Brain Injuries (ortholog); congenital diaphragmatic hernia (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24163,822,402 - 164,461,801 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15161,966,392 - 162,604,913 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05164,029,432 - 164,664,156 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15170,793,386 - 171,425,236 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5170,793,731 - 171,425,242 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLIT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24163,822,402 - 164,461,801 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15161,966,392 - 162,604,913 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05164,029,432 - 164,664,156 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15170,793,386 - 171,425,236 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5170,793,731 - 171,425,242 (-)Ensemblpanpan1.1panPan2
SLIT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385168,661,740 - 169,301,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5168,661,740 - 169,301,139 (-)EnsemblGRCh38hg38GRCh38
GRCh375168,088,745 - 168,728,143 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365168,025,857 - 168,660,554 (-)NCBINCBI36Build 36hg18NCBI36
Build 345168,025,856 - 168,660,554NCBI
Celera5164,128,856 - 164,759,439 (-)NCBICelera
Cytogenetic Map5q34-q35.1NCBI
HuRef5163,187,021 - 163,825,867 (-)NCBIHuRef
CHM1_15167,521,662 - 168,160,538 (-)NCBICHM1_1
T2T-CHM13v2.05169,196,497 - 169,836,714 (-)NCBIT2T-CHM13v2.0
Slit3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,012,283 - 35,599,334 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,012,051 - 35,599,334 (+)EnsemblGRCm39 Ensembl
GRCm381135,121,456 - 35,708,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,121,224 - 35,708,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv371134,934,958 - 35,522,009 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361134,964,879 - 35,551,735 (+)NCBIMGSCv36mm8
Celera1138,900,451 - 39,489,864 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1120.29NCBI
Slit3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81020,075,929 - 20,660,704 (+)NCBIGRCr8
mRatBN7.21019,571,798 - 20,156,634 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1019,571,684 - 20,156,634 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1024,327,438 - 24,913,272 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01023,815,979 - 24,401,801 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01019,295,723 - 19,880,358 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01019,924,200 - 20,517,918 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1020,320,878 - 20,518,518 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01019,801,599 - 20,392,415 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41019,983,166 - 20,576,689 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11020,098,220 - 20,577,738 (+)NCBI
Celera1019,201,522 - 19,782,964 (+)NCBICelera
Cytogenetic Map10q12NCBI
Slit3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540821,722,632 - 22,322,917 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540821,719,487 - 22,322,958 (-)NCBIChiLan1.0ChiLan1.0
SLIT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1442,506,680 - 43,099,053 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl442,508,426 - 43,094,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha442,466,027 - 43,055,860 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0442,928,562 - 43,521,077 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl442,928,887 - 43,516,993 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1442,700,926 - 43,290,974 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0442,893,778 - 43,485,410 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0443,399,255 - 43,991,187 (+)NCBIUU_Cfam_GSD_1.0
Slit3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721396,574,901 - 97,136,840 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936622565,346 - 752,299 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936622191,165 - 756,552 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLIT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1654,553,426 - 55,220,296 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11654,551,536 - 55,221,427 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21659,123,810 - 59,790,312 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLIT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12370,890,096 - 71,524,002 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2370,885,737 - 71,106,703 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660347,156,377 - 7,794,096 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slit3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473320,683,814 - 21,291,088 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473320,683,680 - 21,293,663 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014345150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000043477   ⟹   ENSPPAP00000020681
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5170,793,731 - 171,425,242 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000043489   ⟹   ENSPPAP00000020693
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5170,793,731 - 171,013,590 (-)Ensembl
RefSeq Acc Id: XM_014345150   ⟹   XP_014200636
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24163,822,402 - 164,461,801 (-)NCBI
NHGRI_mPanPan15161,966,392 - 162,604,913 (-)NCBI
Mhudiblu_PPA_v05164,029,432 - 164,664,156 (-)NCBI
PanPan1.15170,793,386 - 171,425,236 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_014200636 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000020681.1
  ENSPPAP00000020693.1
RefSeq Acc Id: XP_014200636   ⟸   XM_014345150
- UniProtKB: A0A2R9ATN7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000020681   ⟸   ENSPPAT00000043477
Ensembl Acc Id: ENSPPAP00000020693   ⟸   ENSPPAT00000043489
Protein Domains
CTCK   EGF-like   Laminin G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033489 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043477.1 UniProtKB/TrEMBL
  ENSPPAT00000043489.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Cys_knot_C UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
  Notch/Slit_guidance UniProtKB/TrEMBL
NCBI Gene SLIT3 ENTREZGENE
PANTHER LRRCT DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  SLIT HOMOLOG UniProtKB/TrEMBL
  SLIT HOMOLOG 3 PROTEIN UniProtKB/TrEMBL
Pfam EGF UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  CTCK_1 UniProtKB/TrEMBL
  CTCK_2 UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  LRR_BAC UniProtKB/TrEMBL
  LRR_RI UniProtKB/TrEMBL
  LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
  SM00041 UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  L domain-like UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A2R9ATN7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AU09_PANPA UniProtKB/TrEMBL