POLD2 (DNA polymerase delta 2, accessory subunit) - Rat Genome Database

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Gene: POLD2 (DNA polymerase delta 2, accessory subunit) Pan paniscus
Analyze
Symbol: POLD2
Name: DNA polymerase delta 2, accessory subunit
RGD ID: 11922705
Description: ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN DNA replication (ortholog); DNA-templated DNA replication (ortholog); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN delta DNA polymerase complex (ortholog); zeta DNA polymerase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DAN polymerase delta 2, accessory subunit; DNA polymerase delta subunit 2; polymerase (DNA directed), delta 2, accessory subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,026,199 - 49,035,160 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,350,939 - 97,359,900 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,829,040 - 44,837,928 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,896,320 - 44,906,084 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,896,320 - 44,905,393 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
POLD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,026,199 - 49,035,160 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,350,939 - 97,359,900 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,829,040 - 44,837,928 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,896,320 - 44,906,084 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,896,320 - 44,905,393 (-)Ensemblpanpan1.1panPan2
POLD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,114,680 - 44,124,325 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,114,631 - 44,124,358 (-)EnsemblGRCh38hg38GRCh38
GRCh37744,154,279 - 44,163,147 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,120,812 - 44,129,655 (-)NCBINCBI36Build 36hg18NCBI36
Build 34743,927,526 - 43,936,370NCBI
Celera744,252,240 - 44,261,103 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef744,039,545 - 44,048,437 (-)NCBIHuRef
CHM1_1744,158,128 - 44,167,020 (-)NCBICHM1_1
T2T-CHM13v2.0744,273,211 - 44,282,858 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,193,774 - 44,202,666 (-)NCBI
Pold2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,822,180 - 5,828,256 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,822,180 - 5,828,292 (-)EnsemblGRCm39 Ensembl
GRCm38115,872,180 - 5,878,256 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,872,180 - 5,878,292 (-)EnsemblGRCm38mm10GRCm38
MGSCv37115,772,183 - 5,778,259 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,772,191 - 5,778,220 (-)NCBIMGSCv36mm8
Celera116,363,816 - 6,369,891 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.88NCBI
Pold2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,962,933 - 84,969,148 (-)NCBIGRCr8
mRatBN7.21480,748,971 - 80,755,188 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,748,974 - 80,755,160 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,151,054 - 85,157,217 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,391,142 - 86,397,305 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,840,464 - 82,846,627 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,111,416 - 86,117,578 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,111,294 - 86,117,578 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,802,860 - 86,809,022 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,535,757 - 86,541,920 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,554,903 - 86,561,065 (-)NCBI
Celera1479,633,799 - 79,639,962 (-)NCBICelera
Cytogenetic Map14q21NCBI
Pold2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,853,476 - 7,860,108 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,853,476 - 7,860,108 (+)NCBIChiLan1.0ChiLan1.0
POLD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,054,909 - 2,062,351 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,799,626 - 14,807,063 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,799,229 - 14,807,248 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,430,844 - 14,438,274 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,411,321 - 14,418,752 (+)NCBIUU_Cfam_GSD_1.0
Pold2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,863,137 - 99,872,322 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,072,810 - 19,083,669 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,074,871 - 19,083,624 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1851,038,358 - 51,046,779 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11851,038,272 - 51,046,782 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,932,004 - 55,940,477 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POLD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,544,083 - 14,553,315 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,545,986 - 14,553,217 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660627,961,746 - 7,970,661 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pold2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,901,075 - 7,908,014 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,901,029 - 7,907,746 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000036232   ⟹   ENSPPAP00000013560
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl744,896,320 - 44,905,393 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036238   ⟹   ENSPPAP00000013565
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl744,896,418 - 44,905,290 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036245   ⟹   ENSPPAP00000013572
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl744,896,418 - 44,905,290 (-)Ensembl
RefSeq Acc Id: XM_003805234   ⟹   XP_003805282
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2649,026,199 - 49,035,160 (-)NCBI
NHGRI_mPanPan1797,350,939 - 97,359,900 (-)NCBI
Mhudiblu_PPA_v0744,829,040 - 44,837,924 (-)NCBI
PanPan1.1744,896,320 - 44,905,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055115893   ⟹   XP_054971868
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2649,026,199 - 49,035,020 (-)NCBI
NHGRI_mPanPan1797,350,939 - 97,359,760 (-)NCBI
RefSeq Acc Id: XM_055115894   ⟹   XP_054971869
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2649,026,199 - 49,035,032 (-)NCBI
NHGRI_mPanPan1797,350,939 - 97,359,772 (-)NCBI
RefSeq Acc Id: XM_055115895   ⟹   XP_054971870
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2649,026,199 - 49,035,032 (-)NCBI
NHGRI_mPanPan1797,350,939 - 97,359,772 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003805282 (Get FASTA)   NCBI Sequence Viewer  
  XP_054971868 (Get FASTA)   NCBI Sequence Viewer  
  XP_054971869 (Get FASTA)   NCBI Sequence Viewer  
  XP_054971870 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000013560.1
  ENSPPAP00000013565.1
  ENSPPAP00000013572.1
Reference Protein Sequences
RefSeq Acc Id: XP_003805282   ⟸   XM_003805234
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A8G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000013572   ⟸   ENSPPAT00000036245
RefSeq Acc Id: ENSPPAP00000013565   ⟸   ENSPPAT00000036238
RefSeq Acc Id: ENSPPAP00000013560   ⟸   ENSPPAT00000036232
RefSeq Acc Id: XP_054971870   ⟸   XM_055115895
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A8F8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054971869   ⟸   XM_055115894
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A8F8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054971868   ⟸   XM_055115893
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A8F8 (UniProtKB/TrEMBL)
Protein Domains
DNA polymerase alpha/delta/epsilon subunit B   DNA polymerase delta subunit OB-fold


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029927 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036232.1 UniProtKB/TrEMBL
  ENSPPAT00000036238.1 UniProtKB/TrEMBL
  ENSPPAT00000036245.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.430 UniProtKB/TrEMBL
  3.60.21.50 UniProtKB/TrEMBL
InterPro DNA_pol_a/d/e_bsu UniProtKB/TrEMBL
  DNA_pol_D_N UniProtKB/TrEMBL
  DNA_pol_delta/II_ssu UniProtKB/TrEMBL
  PolD2_C UniProtKB/TrEMBL
KEGG Report pps:100980787 UniProtKB/TrEMBL
NCBI Gene POLD2 ENTREZGENE
PANTHER DNA POLYMERASE DELTA SUBUNIT 2 UniProtKB/TrEMBL
  PTHR10416 UniProtKB/TrEMBL
Pfam DNA_pol_D_N UniProtKB/TrEMBL
  DNA_pol_E_B UniProtKB/TrEMBL
UniProt A0A2R9A8F8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A8G2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ADS7_PANPA UniProtKB/TrEMBL