NLRP14 (NLR family pyrin domain containing 14) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: NLRP14 (NLR family pyrin domain containing 14) Pan paniscus
Analyze
Symbol: NLRP14
Name: NLR family pyrin domain containing 14
RGD ID: 11922639
Description: INVOLVED IN regulation of inflammatory response (inferred); spermatogenesis (inferred); ASSOCIATED WITH genetic disease (ortholog); spermatogenic failure (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NACHT, LRR and PYD domains-containing protein 14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v299,426,349 - 9,549,015 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1119,391,774 - 9,443,639 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0117,122,928 - 7,174,772 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,805,331 - 6,856,718 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,805,331 - 6,856,718 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NLRP14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v299,426,349 - 9,549,015 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1119,391,774 - 9,443,639 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0117,122,928 - 7,174,772 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,805,331 - 6,856,718 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,805,331 - 6,856,718 (+)Ensemblpanpan1.1panPan2
NLRP14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,020,446 - 7,090,900 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,020,479 - 7,071,526 (+)EnsemblGRCh38hg38GRCh38
GRCh37117,041,710 - 7,092,757 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,998,276 - 7,049,333 (+)NCBINCBI36Build 36hg18NCBI36
Build 34117,016,372 - 7,049,333NCBI
Celera117,160,740 - 7,211,803 (+)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef116,700,195 - 6,751,227 (+)NCBIHuRef
CHM1_1117,040,627 - 7,091,687 (+)NCBICHM1_1
T2T-CHM13v2.0117,078,824 - 7,149,635 (+)NCBIT2T-CHM13v2.0
Nlrp14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397106,712,662 - 106,797,310 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7106,766,197 - 106,797,309 (+)EnsemblGRCm39 Ensembl
GRCm387107,113,455 - 107,198,103 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7107,166,990 - 107,198,102 (+)EnsemblGRCm38mm10GRCm38
MGSCv377114,310,504 - 114,341,617 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367106,958,167 - 106,989,279 (+)NCBIMGSCv36mm8
Celera7107,162,901 - 107,194,394 (+)NCBICelera
Cytogenetic Map7E3NCBI
cM Map756.1NCBI
Nlrp14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81170,472,956 - 170,500,962 (+)NCBIGRCr8
mRatBN7.21161,069,141 - 161,089,158 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1161,061,165 - 161,089,222 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01171,305,558 - 171,340,428 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,306,049 - 171,340,493 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01178,325,007 - 178,343,264 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41164,520,792 - 164,537,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1158,973,913 - 159,002,277 (+)NCBICelera
Cytogenetic Map1q33NCBI
Nlrp14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541422,885,205 - 22,914,343 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541422,885,226 - 22,914,254 (+)NCBIChiLan1.0ChiLan1.0
NLRP14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12130,713,700 - 30,922,332 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2130,713,351 - 30,907,113 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2130,284,577 - 30,328,235 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02131,522,062 - 31,566,213 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2131,522,374 - 31,701,331 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12130,852,579 - 30,894,542 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02131,015,517 - 31,059,147 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02131,310,739 - 31,354,651 (+)NCBIUU_Cfam_GSD_1.0
Nlrp14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494754,715,514 - 54,745,817 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936841341,505 - 371,728 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NLRP14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.192,542,538 - 2,550,430 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.293,013,131 - 3,026,295 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NLRP14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1157,659,342 - 57,793,848 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl157,752,336 - 57,786,254 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038155,503,131 - 155,539,286 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nlrp14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248178,804,529 - 8,832,874 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248178,804,708 - 8,832,251 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000057071   ⟹   ENSPPAP00000034190
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl116,805,331 - 6,856,718 (+)Ensembl
RefSeq Acc Id: XM_003819105   ⟹   XP_003819153
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v299,426,374 - 9,478,238 (+)NCBI
NHGRI_mPanPan1119,391,799 - 9,443,639 (+)NCBI
Mhudiblu_PPA_v0117,122,928 - 7,174,772 (+)NCBI
PanPan1.1116,805,331 - 6,856,718 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055095176   ⟹   XP_054951151
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v299,426,363 - 9,478,238 (+)NCBI
NHGRI_mPanPan1119,391,788 - 9,443,639 (+)NCBI
RefSeq Acc Id: XM_055095177   ⟹   XP_054951152
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v299,426,349 - 9,478,238 (+)NCBI
NHGRI_mPanPan1119,391,774 - 9,443,639 (+)NCBI
RefSeq Acc Id: XM_063608344   ⟹   XP_063464414
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v299,426,397 - 9,549,015 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003819153 (Get FASTA)   NCBI Sequence Viewer  
  XP_054951151 (Get FASTA)   NCBI Sequence Viewer  
  XP_054951152 (Get FASTA)   NCBI Sequence Viewer  
  XP_063464414 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034190.1
Reference Protein Sequences
RefSeq Acc Id: XP_003819153   ⟸   XM_003819105
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSPPAP00000034190   ⟸   ENSPPAT00000057071
RefSeq Acc Id: XP_054951152   ⟸   XM_055095177
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054951151   ⟸   XM_055095176
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063464414   ⟸   XM_063608344
- Peptide Label: isoform X3
Protein Domains
NACHT   Pyrin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039939 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057071.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro DAPIN UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  NACHT_NTPase UniProtKB/TrEMBL
  NLRP_HD2 UniProtKB/TrEMBL
  NOD2_WH UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report pps:100975900 UniProtKB/TrEMBL
NCBI Gene NLRP14 ENTREZGENE
PANTHER NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 UniProtKB/TrEMBL
  NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 14 UniProtKB/TrEMBL
Pfam LRR_6 UniProtKB/TrEMBL
  NACHT UniProtKB/TrEMBL
  NLRC4_HD2 UniProtKB/TrEMBL
  NOD2_WH UniProtKB/TrEMBL
  PYRIN UniProtKB/TrEMBL
PROSITE DAPIN UniProtKB/TrEMBL
  NACHT UniProtKB/TrEMBL
SMART LRR_RI UniProtKB/TrEMBL
  PYRIN UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
  SSF47986 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9C0B5_PANPA UniProtKB/TrEMBL