LOC100987236 (signal recognition particle subunit SRP54) - Rat Genome Database

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Gene: LOC100987236 (signal recognition particle subunit SRP54) Pan paniscus
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Symbol: LOC100987236 (Ensembl: SRP54)
Name: signal recognition particle subunit SRP54 (Ensembl:signal recognition particle 54)
RGD ID: 11921916
Description: ENCODES a protein that exhibits GTPase activity (ortholog); INVOLVED IN SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); ectodermal dysplasia and immunodeficiency 2 (ortholog); genetic disease (ortholog); FOUND IN nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAM177A1; family with sequence similarity 177 member A1; signal recognition particle 54; SRP54
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21536,293,771 - 36,393,170 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11435,510,292 - 35,609,673 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01415,733,446 - 15,779,987 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11433,920,330 - 33,966,023 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1433,920,287 - 34,017,151 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100987236
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21536,293,771 - 36,393,170 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11435,510,292 - 35,609,673 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01415,733,446 - 15,779,987 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11433,920,330 - 33,966,023 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1433,920,287 - 34,017,151 (+)Ensemblpanpan1.1panPan2
SRP54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381434,982,992 - 35,029,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1434,981,957 - 35,029,686 (+)EnsemblGRCh38hg38GRCh38
GRCh371435,452,198 - 35,498,773 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361434,521,982 - 34,568,519 (+)NCBINCBI36Build 36hg18NCBI36
Build 341434,521,981 - 34,568,517NCBI
Celera1415,315,912 - 15,362,600 (+)NCBICelera
Cytogenetic Map14q13.2NCBI
HuRef1415,564,659 - 15,611,702 (+)NCBIHuRef
CHM1_11435,450,690 - 35,497,725 (+)NCBICHM1_1
T2T-CHM13v2.01429,181,721 - 29,228,319 (+)NCBIT2T-CHM13v2.0
Srp54a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391255,127,318 - 55,162,152 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1255,127,047 - 55,162,152 (+)EnsemblGRCm39 Ensembl
GRCm381255,080,476 - 55,115,367 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1255,080,262 - 55,115,367 (+)EnsemblGRCm38mm10GRCm38
MGSCv371256,181,483 - 56,216,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361255,998,696 - 56,031,814 (+)NCBIMGSCv36mm8
Celera1256,371,141 - 56,408,843 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1223.86NCBI
Srp54a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,322,308 - 78,362,017 (+)NCBIGRCr8
mRatBN7.2672,587,584 - 72,626,878 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,587,605 - 72,625,189 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx673,010,076 - 73,047,802 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,316,425 - 73,354,151 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0672,745,035 - 72,782,580 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0675,996,629 - 76,035,768 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,996,643 - 76,034,083 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0685,532,350 - 85,572,100 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4675,446,838 - 75,494,001 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1675,474,626 - 75,478,796 (+)NCBI
Celera671,428,873 - 71,466,500 (+)NCBICelera
Cytogenetic Map6q23NCBI
Srp54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540925,977,226 - 26,016,351 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540925,977,226 - 26,016,351 (-)NCBIChiLan1.0ChiLan1.0
SRP54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1813,800,275 - 13,837,799 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl813,677,760 - 13,837,722 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha813,597,521 - 13,634,635 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0813,907,202 - 13,944,631 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl813,907,474 - 13,944,627 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1813,608,264 - 13,646,077 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0813,673,490 - 13,710,632 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0813,962,922 - 13,999,855 (+)NCBIUU_Cfam_GSD_1.0
LOC101965130
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864045,677,956 - 45,741,100 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364949,183,632 - 9,222,855 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049364949,227,321 - 9,246,955 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364949,183,620 - 9,220,510 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRP54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl764,829,228 - 64,877,195 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1764,829,625 - 64,877,574 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2769,658,033 - 69,706,782 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SRP54
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12411,802,671 - 11,846,534 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2411,812,672 - 11,846,675 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666053764,178 - 808,147 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srp54
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248381,697,863 - 1,747,136 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248381,697,863 - 1,747,115 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000019388   ⟹   ENSPPAP00000004172
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1433,920,287 - 33,966,023 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000019460   ⟹   ENSPPAP00000004187
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1433,933,646 - 34,014,200 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000019485   ⟹   ENSPPAP00000004193
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1433,933,646 - 33,945,422 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000019507   ⟹   ENSPPAP00000004198
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1433,933,701 - 33,965,608 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000019518   ⟹   ENSPPAP00000004204
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1433,979,750 - 34,017,151 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000019548   ⟹   ENSPPAP00000004213
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1433,980,889 - 33,984,562 (+)Ensembl
RefSeq Acc Id: XM_003821192   ⟹   XP_003821240
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21536,293,771 - 36,340,639 (+)NCBI
NHGRI_mPanPan11435,510,345 - 35,557,141 (+)NCBI
Mhudiblu_PPA_v01415,733,446 - 15,779,987 (+)NCBI
PanPan1.11433,920,330 - 33,966,023 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034937433   ⟹   XP_034793324
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21536,355,683 - 36,393,170 (+)NCBI
NHGRI_mPanPan11435,572,185 - 35,609,673 (+)NCBI
RefSeq Acc Id: XM_034937434   ⟹   XP_034793325
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21536,354,378 - 36,393,170 (+)NCBI
NHGRI_mPanPan11435,570,907 - 35,609,673 (+)NCBI
RefSeq Acc Id: XM_055097471   ⟹   XP_054953446
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21536,304,118 - 36,340,639 (+)NCBI
NHGRI_mPanPan11435,520,620 - 35,557,141 (+)NCBI
RefSeq Acc Id: XM_055097472   ⟹   XP_054953447
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21536,293,790 - 36,393,170 (+)NCBI
NHGRI_mPanPan11435,510,292 - 35,609,673 (+)NCBI
RefSeq Acc Id: XP_003821240   ⟸   XM_003821192
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZJZ7 (UniProtKB/TrEMBL),   A0A2R8ZK11 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000004172   ⟸   ENSPPAT00000019388
RefSeq Acc Id: ENSPPAP00000004193   ⟸   ENSPPAT00000019485
RefSeq Acc Id: ENSPPAP00000004187   ⟸   ENSPPAT00000019460
RefSeq Acc Id: ENSPPAP00000004204   ⟸   ENSPPAT00000019518
RefSeq Acc Id: ENSPPAP00000004198   ⟸   ENSPPAT00000019507
RefSeq Acc Id: ENSPPAP00000004213   ⟸   ENSPPAT00000019548
RefSeq Acc Id: XP_054953447   ⟸   XM_055097472
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZK11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054953446   ⟸   XM_055097471
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZJZ7 (UniProtKB/TrEMBL),   A0A2R8ZK11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034793325   ⟸   XM_034937434
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZGU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034793324   ⟸   XM_034937433
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZGU0 (UniProtKB/TrEMBL)

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000017434 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000019388.1 UniProtKB/TrEMBL
  ENSPPAT00000019460.1 UniProtKB/TrEMBL
  ENSPPAT00000019485.1 UniProtKB/TrEMBL
  ENSPPAT00000019507.1 UniProtKB/TrEMBL
  ENSPPAT00000019518.1 UniProtKB/TrEMBL
  ENSPPAT00000019548.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.260.30 UniProtKB/TrEMBL
  1.20.120.140 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  FAM177 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Signal_recog_part_SRP54_M_sf UniProtKB/TrEMBL
  Signal_recog_particl_SRP54_hlx UniProtKB/TrEMBL
  Signal_recog_particle_SRP54_M UniProtKB/TrEMBL
  SRP/SRP_N UniProtKB/TrEMBL
  SRP54 UniProtKB/TrEMBL
  SRP54_euk UniProtKB/TrEMBL
  SRP54_GTPase_dom UniProtKB/TrEMBL
  SRP54_N_sf UniProtKB/TrEMBL
KEGG Report pps:100987236 UniProtKB/TrEMBL
NCBI Gene SRP54 ENTREZGENE
PANTHER PROTEIN FAM177A1 UniProtKB/TrEMBL
  PTHR11564 UniProtKB/TrEMBL
  PTHR31206 UniProtKB/TrEMBL
  SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN UniProtKB/TrEMBL
Pfam FAM177 UniProtKB/TrEMBL
  SRP54 UniProtKB/TrEMBL
  SRP54_N UniProtKB/TrEMBL
  SRP_SPB UniProtKB/TrEMBL
PROSITE SRP54 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
  SRP54 UniProtKB/TrEMBL
  SRP54_N UniProtKB/TrEMBL
Superfamily-SCOP SSF47364 UniProtKB/TrEMBL
  SSF47446 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R8ZGU0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZJZ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZK11 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZN39_PANPA UniProtKB/TrEMBL
  A0A2R8ZN43_PANPA UniProtKB/TrEMBL
  A0A2R8ZN54_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 LOC100987236  signal recognition particle subunit SRP54  SRP54  signal recognition particle 54  Symbol and/or name change 5135510 APPROVED
2023-04-20 SRP54  signal recognition particle 54  FAM177A1  family with sequence similarity 177 member A1  Data merged from RGD:11791884 737654 PROVISIONAL