RGS1 (regulator of G protein signaling 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: RGS1 (regulator of G protein signaling 1) Pan paniscus
Analyze
Symbol: RGS1
Name: regulator of G protein signaling 1
RGD ID: 11920179
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (inferred); GTPase activator activity (inferred); GTPase activity (inferred); INVOLVED IN response to bacterium (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); Arsenic Poisoning (ortholog); COVID-19 (ortholog); FOUND IN cytoplasmic side of plasma membrane (inferred); cytosol (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulator of G-protein signaling 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2157,209,527 - 57,213,812 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1156,873,541 - 56,877,824 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01168,039,235 - 168,043,516 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,333,842 - 172,338,105 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,333,866 - 172,337,401 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
RGS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2157,209,527 - 57,213,812 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1156,873,541 - 56,877,824 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01168,039,235 - 168,043,516 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,333,842 - 172,338,105 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,333,866 - 172,337,401 (+)Ensemblpanpan1.1panPan2
RGS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381192,575,773 - 192,580,024 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1192,575,763 - 192,580,024 (+)EnsemblGRCh38hg38GRCh38
GRCh371192,544,903 - 192,549,154 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361190,811,480 - 190,815,782 (+)NCBINCBI36Build 36hg18NCBI36
Build 341189,276,513 - 189,280,816NCBI
Celera1165,654,672 - 165,658,974 (+)NCBICelera
Cytogenetic Map1q31.2NCBI
HuRef1163,781,164 - 163,785,466 (+)NCBIHuRef
CHM1_11193,966,658 - 193,970,960 (+)NCBICHM1_1
T2T-CHM13v2.01191,922,968 - 191,927,219 (+)NCBIT2T-CHM13v2.0
Rgs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391144,120,407 - 144,124,862 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1144,118,034 - 144,124,980 (-)EnsemblGRCm39 Ensembl
GRCm381144,244,669 - 144,249,104 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1144,242,296 - 144,249,242 (-)EnsemblGRCm38mm10GRCm38
MGSCv371146,091,799 - 146,096,234 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361146,006,887 - 146,011,253 (-)NCBIMGSCv36mm8
Celera1146,807,094 - 146,811,529 (-)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.56NCBI
Rgs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81358,568,844 - 58,573,187 (-)NCBIGRCr8
mRatBN7.21356,018,546 - 56,022,889 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1356,018,554 - 56,022,984 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1358,589,584 - 58,593,926 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01359,843,245 - 59,847,588 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01357,127,442 - 57,131,783 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01361,066,196 - 61,070,772 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1361,066,153 - 61,070,599 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01366,051,575 - 66,055,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41358,121,188 - 58,125,514 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11358,135,995 - 58,136,925 (-)NCBI
Celera1356,094,754 - 56,099,080 (-)NCBICelera
Cytogenetic Map13q21NCBI
Rgs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540630,041,870 - 30,047,752 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540630,042,354 - 30,047,172 (+)NCBIChiLan1.0ChiLan1.0
RGS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1386,372,451 - 6,376,427 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl386,372,558 - 6,376,315 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha386,469,308 - 6,473,654 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0386,389,651 - 6,393,997 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl386,390,151 - 6,393,923 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1386,388,350 - 6,392,690 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0386,754,006 - 6,758,352 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0386,989,727 - 6,994,072 (-)NCBIUU_Cfam_GSD_1.0
Rgs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934481,261,527 - 81,265,779 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936638879,287 - 883,169 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936638879,241 - 883,423 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl101,147,458 - 1,151,738 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1101,147,439 - 1,151,733 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2102,731,386 - 2,735,619 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RGS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,853,413 - 36,868,599 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2536,853,340 - 36,857,663 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605537,822,366 - 37,826,704 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248141,041,784 - 1,045,954 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248141,041,812 - 1,045,961 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003820592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000031065   ⟹   ENSPPAP00000008429
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1172,333,866 - 172,337,401 (+)Ensembl
RefSeq Acc Id: XM_003820592   ⟹   XP_003820640
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2157,209,527 - 57,213,812 (-)NCBI
NHGRI_mPanPan1156,873,541 - 56,877,824 (-)NCBI
Mhudiblu_PPA_v01168,039,235 - 168,043,516 (+)NCBI
PanPan1.11172,333,842 - 172,338,105 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003820640 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000008429.1
Reference Protein Sequences
RefSeq Acc Id: XP_003820640   ⟸   XM_003820592
- UniProtKB: A0A2R8ZTY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000008429   ⟸   ENSPPAT00000031065
Protein Domains
RGS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027449 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000031065.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
  1.10.196.10 UniProtKB/TrEMBL
InterPro RGS UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
NCBI Gene RGS1 ENTREZGENE
PANTHER PTHR10845:SF34 UniProtKB/TrEMBL
  REGULATOR OF G PROTEIN SIGNALING UniProtKB/TrEMBL
Pfam RGS UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE RGS UniProtKB/TrEMBL
SMART RGS UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
UniProt A0A2R8ZTY0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-11-07 RGS1  regulator of G protein signaling 1    regulator of G-protein signaling 1  Symbol and/or name change 5135510 APPROVED