FDX2 (ferredoxin 2) - Rat Genome Database

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Gene: FDX2 (ferredoxin 2) Pan paniscus
Analyze
Symbol: FDX2
Name: ferredoxin 2
RGD ID: 11916664
Description: ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (inferred); electron transfer activity (inferred); iron-sulfur cluster binding (inferred); INVOLVED IN [4Fe-4S] cluster assembly (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH familial hypercholesterolemia (ortholog); genetic disease (ortholog); immunodeficiency 35 (ortholog); FOUND IN mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adrenodoxin-like protein, mitochondrial; adrenodoxin-like protein, mitochondrial-like; FDX1L; ferredoxin 1 like; ferredoxin-2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22015,227,211 - 15,232,999 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11914,225,844 - 14,231,631 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,860,316 - 9,866,442 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,520,072 - 10,532,163 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,526,287 - 10,532,152 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FDX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22015,227,211 - 15,232,999 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11914,225,844 - 14,231,631 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,860,316 - 9,866,442 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,520,072 - 10,532,163 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,526,287 - 10,532,152 (-)Ensemblpanpan1.1panPan2
FDX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,310,045 - 10,316,015 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,309,916 - 10,316,015 (-)EnsemblGRCh38hg38GRCh38
GRCh371910,420,721 - 10,426,691 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,281,891 - 10,287,691 (-)NCBINCBI36Build 36hg18NCBI36
Celera1910,316,284 - 10,322,080 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef1910,001,153 - 10,006,949 (-)NCBIHuRef
CHM1_11910,421,449 - 10,427,224 (-)NCBICHM1_1
T2T-CHM13v2.01910,436,158 - 10,442,125 (-)NCBIT2T-CHM13v2.0
Fdx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,978,808 - 20,984,827 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,978,816 - 20,984,910 (-)EnsemblGRCm39 Ensembl
GRCm38921,067,512 - 21,073,531 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,067,520 - 21,073,614 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,871,964 - 20,877,958 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,817,920 - 20,823,946 (-)NCBIMGSCv36mm8
Celera918,336,235 - 18,342,228 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.7NCBI
Fdx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,881,091 - 27,886,230 (-)NCBIGRCr8
mRatBN7.2819,604,916 - 19,609,832 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,604,916 - 19,609,849 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx823,624,325 - 23,629,241 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,922,179 - 21,927,095 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,834,580 - 19,839,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0822,086,534 - 22,091,450 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,086,534 - 22,091,450 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,143,206 - 22,148,122 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,091,424 - 20,096,340 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera820,999,337 - 21,004,253 (-)NCBICelera
Cytogenetic Map8q13NCBI
Fdx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,590,493 - 1,594,760 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,590,493 - 1,594,760 (-)NCBIChiLan1.0ChiLan1.0
FDX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,798,250 - 50,802,477 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,668,057 - 50,672,225 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,319,937 - 51,324,100 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,319,932 - 51,324,048 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,526,079 - 50,530,247 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02050,954,844 - 50,959,011 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,195,971 - 51,200,136 (+)NCBIUU_Cfam_GSD_1.0
LOC101962614
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,704,318 - 209,714,514 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936659640,587 - 644,804 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_004936659645,191 - 650,246 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936659640,243 - 650,350 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FDX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,359,446 - 9,364,702 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl69,359,719 - 9,364,689 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607410,673,535 - 10,679,013 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fdx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,468,757 - 2,473,600 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248282,468,761 - 2,473,657 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034946488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000013849   ⟹   ENSPPAP00000002967
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1910,526,287 - 10,532,152 (-)Ensembl
RefSeq Acc Id: XM_034946488   ⟹   XP_034802379
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22015,227,211 - 15,232,999 (-)NCBI
NHGRI_mPanPan11914,225,844 - 14,231,631 (-)NCBI
Mhudiblu_PPA_v0199,860,316 - 9,866,442 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034802379 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000002967.1
RefSeq Acc Id: XP_034802379   ⟸   XM_034946488
- UniProtKB: A0A2R8ZDJ1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000002967   ⟸   ENSPPAT00000013849
Protein Domains
2Fe-2S ferredoxin-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000012689 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000013849.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.20.30 UniProtKB/TrEMBL
InterPro 2Fe-2S_ferredoxin-like_sf UniProtKB/TrEMBL
  2Fe-2S_ferredoxin-type UniProtKB/TrEMBL
  Adrenodoxin UniProtKB/TrEMBL
  Adrenodoxin_Fe-S_BS UniProtKB/TrEMBL
  Beta-grasp_dom_sf UniProtKB/TrEMBL
NCBI Gene FDX1L ENTREZGENE
PANTHER FERREDOXIN-2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR23426 UniProtKB/TrEMBL
Pfam Fer2 UniProtKB/TrEMBL
PRINTS ADRENODOXIN UniProtKB/TrEMBL
PROSITE 2FE2S_FER_2 UniProtKB/TrEMBL
  ADX UniProtKB/TrEMBL
Superfamily-SCOP SSF54292 UniProtKB/TrEMBL
UniProt A0A2R8ZDJ1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-04-10 FDX2  ferredoxin 2  FDX1L  ferredoxin 1 like  Symbol and/or name change 5135510 APPROVED