PADI1 (peptidyl arginine deiminase 1) - Rat Genome Database

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Gene: PADI1 (peptidyl arginine deiminase 1) Pan paniscus
Analyze
Symbol: PADI1
Name: peptidyl arginine deiminase 1
RGD ID: 11915763
Description: ENCODES a protein that exhibits protein-arginine deiminase activity (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein-arginine deiminase type-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21209,883,230 - 209,923,725 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,002,081 - 209,042,579 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,150,407 - 16,190,901 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,205,538 - 17,245,972 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,205,452 - 17,245,972 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PADI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21209,883,230 - 209,923,725 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,002,081 - 209,042,579 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,150,407 - 16,190,901 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,205,538 - 17,245,972 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,205,452 - 17,245,972 (+)Ensemblpanpan1.1panPan2
PADI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,205,128 - 17,246,007 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,205,128 - 17,246,007 (+)EnsemblGRCh38hg38GRCh38
GRCh37117,531,623 - 17,572,502 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,404,208 - 17,445,088 (+)NCBINCBI36Build 36hg18NCBI36
Build 34117,276,935 - 17,316,654NCBI
Celera115,854,608 - 15,895,194 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,775,640 - 15,816,163 (+)NCBIHuRef
CHM1_1117,640,028 - 17,680,932 (+)NCBICHM1_1
T2T-CHM13v2.0117,016,414 - 17,057,242 (+)NCBIT2T-CHM13v2.0
Padi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,540,292 - 140,573,089 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,540,294 - 140,573,089 (-)EnsemblGRCm39 Ensembl
GRCm384140,812,981 - 140,845,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,812,983 - 140,845,778 (-)EnsemblGRCm38mm10GRCm38
MGSCv374140,368,896 - 140,401,693 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,085,057 - 140,117,854 (-)NCBIMGSCv36mm8
Celera4142,625,585 - 142,659,167 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map472.62NCBI
Padi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,402,614 - 158,435,077 (-)NCBIGRCr8
mRatBN7.25153,119,566 - 153,152,034 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,119,566 - 153,152,034 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,808,770 - 155,842,124 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,583,072 - 157,615,507 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,571,691 - 157,604,213 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,338,850 - 159,371,313 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,338,850 - 159,371,313 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,045,278 - 163,077,738 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,671,725 - 159,704,188 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,681,912 - 159,714,376 (-)NCBI
Celera5151,477,068 - 151,509,531 (-)NCBICelera
Cytogenetic Map5q36NCBI
Padi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,610,064 - 1,642,379 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,610,643 - 1,641,953 (-)NCBIChiLan1.0ChiLan1.0
PADI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1280,997,563 - 81,036,942 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl280,996,021 - 81,036,942 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,533,555 - 77,574,493 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,643,691 - 81,684,606 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,643,693 - 81,689,788 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,396,618 - 78,437,587 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,412,393 - 79,453,539 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,482,086 - 80,523,026 (-)NCBIUU_Cfam_GSD_1.0
Padi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,282,998 - 38,338,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364744,134,737 - 4,161,958 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364744,121,948 - 4,163,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PADI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,830,046 - 75,871,911 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,830,053 - 75,871,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2670,173,382 - 70,214,300 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PADI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,341,430 - 115,388,234 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,343,203 - 115,381,634 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666033731,523 - 778,340 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000065507   ⟹   ENSPPAP00000042577
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl117,205,452 - 17,245,972 (+)Ensembl
RefSeq Acc Id: XM_003814447   ⟹   XP_003814495
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21209,883,230 - 209,923,725 (-)NCBI
NHGRI_mPanPan11209,002,081 - 209,042,579 (-)NCBI
Mhudiblu_PPA_v0116,150,407 - 16,190,901 (+)NCBI
PanPan1.1117,205,538 - 17,245,972 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055097548   ⟹   XP_054953523
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21209,883,230 - 209,908,351 (-)NCBI
NHGRI_mPanPan11209,002,081 - 209,027,229 (-)NCBI
RefSeq Acc Id: XM_055097554   ⟹   XP_054953529
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21209,883,230 - 209,914,849 (-)NCBI
NHGRI_mPanPan11209,002,081 - 209,033,703 (-)NCBI
RefSeq Acc Id: XM_055097556   ⟹   XP_054953531
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21209,883,230 - 209,908,351 (-)NCBI
NHGRI_mPanPan11209,002,081 - 209,027,229 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003814495 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953523 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953529 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953531 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000042577
  ENSPPAP00000042577.1
Reference Protein Sequences
RefSeq Acc Id: XP_003814495   ⟸   XM_003814447
- Peptide Label: isoform X4
- UniProtKB: A0A2R9CST9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000042577   ⟸   ENSPPAT00000065507
RefSeq Acc Id: XP_054953529   ⟸   XM_055097554
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054953531   ⟸   XM_055097556
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054953523   ⟸   XM_055097548
- Peptide Label: isoform X1
Protein Domains
Protein-arginine deiminase (PAD) central   Protein-arginine deiminase (PAD) N-terminal   Protein-arginine deiminase C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043847 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000065507.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1700 UniProtKB/TrEMBL
  2.60.40.1860 UniProtKB/TrEMBL
InterPro Cupredoxin UniProtKB/TrEMBL
  PAD UniProtKB/TrEMBL
  PAD_C UniProtKB/TrEMBL
  PAD_central_sf UniProtKB/TrEMBL
  PAD_N UniProtKB/TrEMBL
  PAD_N_sf UniProtKB/TrEMBL
  Prot_Arg_deaminase_cen_dom UniProtKB/TrEMBL
KEGG Report pps:100988210 UniProtKB/TrEMBL
NCBI Gene PADI1 ENTREZGENE
PANTHER PROTEIN-ARGININE DEIMINASE TYPE-1 UniProtKB/TrEMBL
  PTHR10837 UniProtKB/TrEMBL
Pfam PAD UniProtKB/TrEMBL
  PAD_M UniProtKB/TrEMBL
  PAD_N UniProtKB/TrEMBL
PIRSF Protein-arginine_deiminase UniProtKB/TrEMBL
Superfamily-SCOP Pentein UniProtKB/TrEMBL
  SSF110083 UniProtKB/TrEMBL
  SSF49503 UniProtKB/TrEMBL
UniProt A0A2R9CST9 ENTREZGENE, UniProtKB/TrEMBL