MPHOSPH8 (M-phase phosphoprotein 8) - Rat Genome Database

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Gene: MPHOSPH8 (M-phase phosphoprotein 8) Pan paniscus
Analyze
Symbol: MPHOSPH8
Name: M-phase phosphoprotein 8
RGD ID: 11912909
Description: ENCODES a protein that exhibits chromatin binding (inferred); histone reader activity (inferred); methylated histone binding (inferred); INVOLVED IN negative regulation of gene expression via chromosomal CpG island methylation (inferred); negative regulation of gene expression, epigenetic (inferred); negative regulation of single stranded viral RNA replication via double stranded DNA intermediate (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21419,234,717 - 19,302,989 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11310,348,090 - 10,415,493 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v013932,620 - 999,853 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11319,278,025 - 19,317,962 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1319,278,149 - 19,316,389 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MPHOSPH8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21419,234,717 - 19,302,989 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11310,348,090 - 10,415,493 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v013932,620 - 999,853 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11319,278,025 - 19,317,962 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1319,278,149 - 19,316,389 (+)Ensemblpanpan1.1panPan2
MPHOSPH8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381319,633,659 - 19,673,441 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1319,633,659 - 19,673,441 (+)EnsemblGRCh38hg38GRCh38
GRCh371320,207,799 - 20,247,581 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361319,105,880 - 19,144,657 (+)NCBINCBI36Build 36hg18NCBI36
Celera131,269,626 - 1,309,437 (+)NCBICelera
Cytogenetic Map13q12.11NCBI
HuRef131,012,645 - 1,052,544 (+)NCBIHuRef
CHM1_11320,175,708 - 20,215,502 (+)NCBICHM1_1
T2T-CHM13v2.01318,797,911 - 18,869,507 (+)NCBIT2T-CHM13v2.0
Mphosph8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391456,905,692 - 56,934,887 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1456,905,705 - 56,934,887 (+)EnsemblGRCm39 Ensembl
GRCm381456,668,235 - 56,697,430 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1456,668,248 - 56,697,430 (+)EnsemblGRCm38mm10GRCm38
MGSCv371457,287,085 - 57,316,267 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361455,622,358 - 55,651,540 (+)NCBIMGSCv36mm8
Celera1454,466,003 - 54,495,185 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.37NCBI
Mphosph8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81534,916,169 - 34,944,038 (+)NCBIGRCr8
mRatBN7.21530,800,546 - 30,828,415 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1530,686,613 - 30,828,810 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1532,791,887 - 32,819,756 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01533,942,544 - 33,970,413 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01532,200,639 - 32,228,508 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01536,918,843 - 36,946,712 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1536,918,843 - 36,946,708 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01540,771,173 - 40,799,042 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41535,667,102 - 35,694,910 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11535,682,838 - 35,710,372 (+)NCBI
Celera1530,514,279 - 30,542,138 (+)NCBICelera
Cytogenetic Map15p12NCBI
Mphosph8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955497518,462 - 546,748 (+)NCBIChiLan1.0ChiLan1.0
MPHOSPH8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12518,392,706 - 18,443,241 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2518,392,409 - 18,443,241 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2518,422,224 - 18,472,279 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02518,530,835 - 18,580,906 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2518,530,543 - 18,580,906 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12518,396,529 - 18,446,575 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02518,408,694 - 18,458,742 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02518,465,473 - 18,515,535 (-)NCBIUU_Cfam_GSD_1.0
Mphosph8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945120,424,420 - 120,477,663 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367201,972,119 - 2,025,332 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367201,972,063 - 2,025,283 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPHOSPH8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl11447,052 - 480,121 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.111447,019 - 480,121 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,858,318 - 86,891,407 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPHOSPH8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.131,261,094 - 1,296,855 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl31,261,631 - 1,295,823 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605743,269,399 - 43,304,050 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mphosph8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477617,998,779 - 18,030,027 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034936381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000030745   ⟹   ENSPPAP00000008110
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1319,278,149 - 19,316,389 (+)Ensembl
RefSeq Acc Id: XM_034936381   ⟹   XP_034792272
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21419,234,717 - 19,302,989 (+)NCBI
NHGRI_mPanPan11310,348,090 - 10,415,493 (+)NCBI
Mhudiblu_PPA_v013932,621 - 999,853 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034792272 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000008110.1
Reference Protein Sequences
RefSeq Acc Id: XP_034792272   ⟸   XM_034936381
- UniProtKB: A0A2R8ZU75 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000008110   ⟸   ENSPPAT00000030745
Protein Domains
Chromo


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027281 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030745.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  2.40.50.40 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Chromo-like_dom_sf UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
NCBI Gene MPHOSPH8 ENTREZGENE
PANTHER CHROMO DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  SI:CH211-189E2.2 UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  Chromo UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  CHROMO UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
  SSF54160 UniProtKB/TrEMBL
UniProt A0A2R8ZU75 ENTREZGENE, UniProtKB/TrEMBL