A4GNT (alpha-1,4-N-acetylglucosaminyltransferase)

Gene: A4GNT (alpha-1,4-N-acetylglucosaminyltransferase) Pan paniscus

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Symbol:

A4GNT

Name:

alpha-1,4-N-acetylglucosaminyltransferase

RGD ID:

11912564

Description:

ENCODES a protein that exhibits acetylglucosaminyltransferase activity (inferred); glycosyltransferase activity (inferred); hexosyltransferase activity (inferred); INVOLVED IN epithelial cell proliferation (ortholog); glycoprotein biosynthetic process (ortholog); negative regulation of epithelial cell proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); pancreatic cancer (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	136,028,637 - 136,037,305 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	136,033,366 - 136,042,034 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	135,151,027 - 135,159,692 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	142,602,475 - 142,610,835 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	142,602,475 - 142,610,835 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

pancreatic cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

epithelial cell proliferation (IEA,ISO)

glycoprotein biosynthetic process (IEA,ISO)

negative regulation of epithelial cell proliferation (IEA,ISO)

protein O-linked glycosylation (IEA,ISO)

Cellular Component

Golgi apparatus (IEA)

Golgi membrane (IEA)

membrane (IEA)

Molecular Function

acetylglucosaminyltransferase activity (IEA)

glycosyltransferase activity (IEA)

hexosyltransferase activity (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

A4GNT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	136,028,637 - 136,037,305 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	136,033,366 - 136,042,034 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	135,151,027 - 135,159,692 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	142,602,475 - 142,610,835 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	142,602,475 - 142,610,835 (-)	Ensembl	panpan1.1		panPan2

A4GNT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	138,123,713 - 138,133,302 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	138,123,713 - 138,132,390 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	137,842,555 - 137,851,232 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	139,325,756 - 139,333,897 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	136,267,340 - 136,276,009 (-)	NCBI		Celera
Cytogenetic Map	3	q22.3	NCBI
HuRef	3	135,217,324 - 135,225,993 (-)	NCBI		HuRef
CHM1_1	3	137,806,379 - 137,815,048 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	140,864,300 - 140,873,888 (-)	NCBI		T2T-CHM13v2.0

A4gnt
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	99,473,233 - 99,504,420 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	99,494,555 - 99,504,420 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	99,591,179 - 99,622,367 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	99,612,502 - 99,622,367 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	99,512,921 - 99,522,786 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	99,421,854 - 99,431,719 (+)	NCBI		MGSCv36	mm8
Celera	9	99,148,870 - 99,158,739 (+)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI
cM Map	9	51.91	NCBI

A4gnt
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	109,050,362 - 109,058,539 (+)	NCBI		GRCr8
mRatBN7.2	8	100,172,038 - 100,179,218 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	100,172,104 - 100,178,569 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	8	107,856,853 - 107,866,438 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	107,859,366 - 107,865,789 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	107,282,862 - 107,290,193 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	104,476,664 - 104,491,166 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	8	99,569,661 - 99,579,946 (+)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

A4gnt
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955501	881,851 - 887,639 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955501	881,851 - 887,977 (+)	NCBI	ChiLan1.0	ChiLan1.0

A4GNT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	34,339,955 - 34,352,204 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	34,341,628 - 34,348,068 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	34,332,534 - 34,344,786 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	34,879,898 - 34,892,137 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	34,880,571 - 34,888,069 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	34,561,786 - 34,574,038 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	34,627,173 - 34,639,418 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	34,878,243 - 34,890,497 (-)	NCBI		UU_Cfam_GSD_1.0

A4gnt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	73,739,415 - 73,744,589 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936540	479,290 - 484,370 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936540	479,290 - 484,370 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

A4GNT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	78,923,681 - 78,932,504 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	78,921,212 - 78,932,575 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	86,522,225 - 86,529,461 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

A4GNT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	52,407,272 - 52,417,129 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	52,410,321 - 52,416,867 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	25,422,500 - 25,431,991 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

A4gnt
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	14,634,480 - 14,640,070 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	14,634,378 - 14,640,070 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003822482	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063602702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000046114 ⟹ ENSPPAP00000023292

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	142,602,475 - 142,610,835 (-)	Ensembl

RefSeq Acc Id:

XM_003822482 ⟹ XP_003822530

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	136,028,637 - 136,037,305 (-)	NCBI
NHGRI_mPanPan1	3	136,033,366 - 136,042,034 (-)	NCBI
Mhudiblu_PPA_v0	3	135,151,027 - 135,159,692 (-)	NCBI
PanPan1.1	3	142,602,475 - 142,610,835 (-)	NCBI

Sequence:

show sequence

ATTTCTAAGACCTCAAATACTGGTTAACTGCGTTTGCAGCTAGAAGTTAGGCTCTGATTCACTG
TTTTGTATTTTCTAAAAGGGTTATATGTAATTTGAAAGATAGACCTGCCAAGACGTGAGATCTG
TGTTCTCCTTGGTTAGAGCTAACATTTATGGTGAGGAAAGCACTGCAGGAGCAGGCTGGCACAG
AGAAGAGGACATGCGGAAGGAGCTCCAGCTTTCCCTGTCAGTCACCTTGCTGCTTGTCTGTGGC
TTCCTCTACCAGTTCACCCTGAAGTCCAGCTGCCTCTTCTGCTTGCCTTCTTTCAAGTCCCACC
AGGGACTGGAAGCCCTCCTGAGCCACAGACGTGGCATTGTGTTTCTAGAGACCTCAGACAGAAT
GGAGCCACCCCACTTGGTCTCCTGTTCTGTAGAGTCTGCTGCCAAGATTTATCCTGAGTGGCCT
GTGGTATTCTTTATGAAGGGTCTTACTGATTCCACACCGATGCCCTCAAACTCCACATACCCAG
CTTTTTCCTTCCTCTCAGCAATAGACAACGTTTTTCTCTTCCCTTTGGATATGAAAAGGCTGCT
TGAAGACACACCATTGTTTTCATGGTACAATCAAATCAACGCCAGCGCAGAGAGAAACTGGCTC
CACATCAGCTCGGATGCATCCCGCCTGGCCATCATCTGGAAATACGGTGGCATCTACATGGACA
CCGATGTCATCTCCATCAGGCCCATCCCTGAGGAGAACTTTTTGGCTGCGCAGGCTTCTCGGTA
CTCCAGTAATGGAATATTTGGGTTCCTCCCCCACCACCCCTTTTTGTGGGAATGCATGGAAAAC
TTTGTTGAACACTATAATTCAGACATTTGGGGCAACCAAGGCCCTGAGTTGATGACAAGGATGT
TGAGGGTATGGTGTAAACTTGAAGACTTCCAGGAGGTGAGTGACCTCAGGTGTCTGAACATATC
CTTCTTACACCCCCAAAGATTTTACCCCATCTCCTATCGAGAGTGGAGGCGCTACTATGAAGTG
TGGGATACAGACCCAAACTTCAATGACTCTTACGCCCTGCATTTGTGGAACCACATGAACCAGG
AGGGGCGGGCTGTGATTAGAGGAAGCAACACACTGGTGGAAAATCTCTATCGCAAGCACTGTCC
CAGGACTTACAGGGACCTGATTAAAGGCCCAGAGGGGTCAGTGACTGGGGAGCTGGGTCCGGGT
AACAAATAGAGCTAACACTCGTTTGCTGCTGCTGCAGTGTGGAAATGGACATTTCCTGGAGTGC
CACATTTTCACTTGATCTCCACTGTCTCTTGGGGGGGTGGGCAGAGGGTTGCCTCTCAAATGTC
AGTTAGGATTAGCTTTCTCTGTCTATAATAGAACAATCCCAAATGATACTGGCTATAAAACATA
CACCCATGGTCCATGTGACTGCTTGACCTCCAACCCACCATGTTTGCATTTCAGGCAGTAGGAT
GAAGAAAAGAGGAAAGGTGCACTTGCTTTATTTTGTGAAGACTTCCTGCAAGTACTGTATAACA
CTTTCTCTTACATTGCACTGACTGAGATGTAGCTGCAAGAGAGGCTGGGAAGTTTAAGGAGGAA
GAAAAAATGGGTACTGGGATAGGCAGCTAACAGTTTTGCTACAAGTTCTATTTAATACAGTAAG
ATTAATTCCAGGACCTGTTAGAGCATTGACTGAGGTAAAAAGAGACTTGATTTCTAGTCCTGAT
TTTGACATTCATTAATGCATTCAGTCAATAAATATTAACTGAG

hide sequence

RefSeq Acc Id:

XM_063602702 ⟹ XP_063458772

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	136,029,135 - 136,036,520 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003822530	(Get FASTA)	NCBI Sequence Viewer
	XP_063458772	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000023292
	ENSPPAP00000023292.1

RefSeq Acc Id:

XP_003822530 ⟸ XM_003822482

- UniProtKB:

A0A2R9B7L5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRKELQLSLSVTLLLVCGFLYQFTLKSSCLFCLPSFKSHQGLEALLSHRRGIVFLETSDRMEPP
HLVSCSVESAAKIYPEWPVVFFMKGLTDSTPMPSNSTYPAFSFLSAIDNVFLFPLDMKRLLEDT
PLFSWYNQINASAERNWLHISSDASRLAIIWKYGGIYMDTDVISIRPIPEENFLAAQASRYSSN
GIFGFLPHHPFLWECMENFVEHYNSDIWGNQGPELMTRMLRVWCKLEDFQEVSDLRCLNISFLH
PQRFYPISYREWRRYYEVWDTDPNFNDSYALHLWNHMNQEGRAVIRGSNTLVENLYRKHCPRTY
RDLIKGPEGSVTGELGPGNK

hide sequence

RefSeq Acc Id:

ENSPPAP00000023292 ⟸ ENSPPAT00000046114

RefSeq Acc Id:	XP_063458772 ⟸ XM_063602702
- UniProtKB:	A0A2R9B7L5 (UniProtKB/TrEMBL)

Protein Domains

Alpha 1,4-glycosyltransferase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034830	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000046114.1	UniProtKB/TrEMBL
Gene3D-CATH	3.90.550.20	UniProtKB/TrEMBL
InterPro	A1-4-GlycosylTfrase_dom	UniProtKB/TrEMBL
	GlycoTrfase_DXD_sugar-bd_CS	UniProtKB/TrEMBL
	Nucleotide-diphossugar_trans	UniProtKB/TrEMBL
KEGG Report	pps:100975245	UniProtKB/TrEMBL
NCBI Gene	A4GNT	ENTREZGENE
PANTHER	ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE	UniProtKB/TrEMBL
	LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE	UniProtKB/TrEMBL
Pfam	Gb3_synth	UniProtKB/TrEMBL
	Gly_transf_sug	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53448	UniProtKB/TrEMBL
UniProt	A0A2R9B7L5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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