OSGIN1 (oxidative stress induced growth inhibitor 1) - Rat Genome Database

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Gene: OSGIN1 (oxidative stress induced growth inhibitor 1) Pan paniscus
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Symbol: OSGIN1
Name: oxidative stress induced growth inhibitor 1
RGD ID: 11911685
Description: ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN negative regulation of cell growth (inferred); signal transduction (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Malonic Aciduria (ortholog); persistent fetal circulation syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100980882; oxidative stress-induced growth inhibitor 1
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21893,679,420 - 93,714,857 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11699,596,537 - 99,631,845 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01664,555,632 - 64,590,930 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11683,942,912 - 83,978,111 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1683,942,912 - 83,978,111 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
OSGIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21893,679,420 - 93,714,857 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11699,596,537 - 99,631,845 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01664,555,632 - 64,590,930 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11683,942,912 - 83,978,111 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1683,942,912 - 83,978,111 (+)Ensemblpanpan1.1panPan2
OSGIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381683,953,240 - 83,966,332 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1683,931,311 - 83,966,332 (+)EnsemblGRCh38hg38GRCh38
GRCh371683,986,845 - 83,999,937 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361682,540,173 - 82,557,438 (+)NCBINCBI36Build 36hg18NCBI36
Celera1668,283,632 - 68,302,337 (+)NCBICelera
Cytogenetic Map16q23.3NCBI
HuRef1669,737,904 - 69,751,578 (+)NCBIHuRef
CHM1_11685,398,355 - 85,411,465 (+)NCBICHM1_1
T2T-CHM13v2.01690,019,300 - 90,032,388 (+)NCBIT2T-CHM13v2.0
Osgin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,160,874 - 120,172,996 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8120,160,863 - 120,172,995 (+)EnsemblGRCm39 Ensembl
GRCm388119,425,882 - 119,446,257 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8119,434,124 - 119,446,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv378121,961,062 - 121,970,156 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368122,323,139 - 122,332,233 (+)NCBIMGSCv36mm8
Celera8123,654,251 - 123,663,345 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map867.71NCBI
Osgin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,380,336 - 64,409,165 (+)NCBIGRCr8
mRatBN7.21947,471,750 - 47,500,517 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,492,171 - 47,500,516 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1954,279,628 - 54,294,893 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01954,960,419 - 54,975,701 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,173,810 - 57,189,105 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,056,808 - 52,085,491 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,077,109 - 52,085,496 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01962,818,232 - 62,834,031 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41949,675,215 - 49,690,479 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11949,680,095 - 49,695,359 (+)NCBI
Celera1946,744,527 - 46,759,791 (+)NCBICelera
Cytogenetic Map19q12NCBI
OSGIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1568,344,406 - 68,377,842 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha568,358,285 - 68,392,074 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0568,642,665 - 68,676,414 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl568,642,008 - 68,676,232 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1568,590,364 - 68,624,216 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0568,426,772 - 68,460,641 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0568,842,573 - 68,876,492 (-)NCBIUU_Cfam_GSD_1.0
Osgin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934928,050,244 - 28,075,053 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366413,803,767 - 3,813,041 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366413,803,799 - 3,812,995 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSGIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl64,642,764 - 4,653,487 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.164,642,762 - 4,656,113 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
OSGIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1569,365,072 - 69,378,319 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl569,365,096 - 69,378,319 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660476,409,526 - 6,422,520 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Osgin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247463,577,184 - 3,610,079 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000030208   ⟹   ENSPPAP00000007669
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1683,942,912 - 83,978,111 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000030213   ⟹   ENSPPAP00000007673
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1683,962,410 - 83,977,786 (+)Ensembl
RefSeq Acc Id: XM_034940810   ⟹   XP_034796701
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21893,679,420 - 93,714,857 (+)NCBI
NHGRI_mPanPan11699,596,537 - 99,631,845 (+)NCBI
Mhudiblu_PPA_v01664,555,632 - 64,590,930 (+)NCBI
RefSeq Acc Id: XM_055100544   ⟹   XP_054956519
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21893,701,797 - 93,714,857 (+)NCBI
NHGRI_mPanPan11699,618,782 - 99,631,845 (+)NCBI
RefSeq Acc Id: XM_055100545   ⟹   XP_054956520
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21893,679,422 - 93,714,857 (+)NCBI
NHGRI_mPanPan11699,596,539 - 99,631,845 (+)NCBI
RefSeq Acc Id: XM_055100547   ⟹   XP_054956522
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21893,701,801 - 93,714,857 (+)NCBI
NHGRI_mPanPan11699,618,801 - 99,631,845 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034796701 (Get FASTA)   NCBI Sequence Viewer  
  XP_054956519 (Get FASTA)   NCBI Sequence Viewer  
  XP_054956520 (Get FASTA)   NCBI Sequence Viewer  
  XP_054956522 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000007669.1
  ENSPPAP00000007673.1
RefSeq Acc Id: XP_034796701   ⟸   XM_034940810
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZSZ9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000007673   ⟸   ENSPPAT00000030213
Ensembl Acc Id: ENSPPAP00000007669   ⟸   ENSPPAT00000030208
RefSeq Acc Id: XP_054956520   ⟸   XM_055100545
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZSZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054956519   ⟸   XM_055100544
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZSZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054956522   ⟸   XM_055100547
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026986 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030208.1 UniProtKB/TrEMBL
  ENSPPAT00000030213.1 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/TrEMBL
InterPro FAD/NAD-bd_sf UniProtKB/TrEMBL
  OKL38_fam UniProtKB/TrEMBL
NCBI Gene OSGIN1 ENTREZGENE
PANTHER PTHR15192 UniProtKB/TrEMBL
  PTHR15192:SF15 UniProtKB/TrEMBL
Superfamily-SCOP SSF51905 UniProtKB/TrEMBL
UniProt A0A2R8ZRT1_PANPA UniProtKB/TrEMBL
  A0A2R8ZSZ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 OSGIN1  oxidative stress induced growth inhibitor 1  LOC100980882  oxidative stress-induced growth inhibitor 1  Symbol and/or name change 5135510 APPROVED
2023-04-20 LOC100980882  oxidative stress-induced growth inhibitor 1  OSGIN1  oxidative stress induced growth inhibitor 1  Data merged from RGD:32729277 737654 PROVISIONAL
2020-07-01 LOC100980882  oxidative stress-induced growth inhibitor 1  OSGIN1  oxidative stress induced growth inhibitor 1  Symbol and/or name change 5135510 APPROVED