CDH18 (cadherin 18) - Rat Genome Database

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Gene: CDH18 (cadherin 18) Pan paniscus
Analyze
Symbol: CDH18
Name: cadherin 18
RGD ID: 11910316
Description: ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN adherens junction organization (inferred); calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (inferred); cell adhesion (inferred); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); speech-language disorder-1 (ortholog); FOUND IN adherens junction (inferred); catenin complex (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cadherin-18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2489,805,974 - 90,910,644 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1587,959,625 - 89,064,289 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0589,870,613 - 90,970,909 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1595,432,743 - 96,533,064 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl596,163,304 - 96,531,116 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CDH18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2489,805,974 - 90,910,644 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1587,959,625 - 89,064,289 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0589,870,613 - 90,970,909 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1595,432,743 - 96,533,064 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl596,163,304 - 96,531,116 (+)Ensemblpanpan1.1panPan2
CDH18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38519,471,296 - 20,575,713 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl519,471,296 - 20,575,873 (-)EnsemblGRCh38hg38GRCh38
GRCh37519,471,405 - 20,575,822 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36519,508,898 - 20,017,046 (-)NCBINCBI36Build 36hg18NCBI36
Build 34519,508,913 - 20,017,046NCBI
Celera520,134,951 - 20,650,014 (-)NCBICelera
Cytogenetic Map5p14.3NCBI
HuRef519,366,653 - 19,882,067 (-)NCBIHuRef
CHM1_1519,472,997 - 19,988,121 (-)NCBICHM1_1
T2T-CHM13v2.0519,473,122 - 20,577,815 (-)NCBIT2T-CHM13v2.0
Cdh18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391522,548,984 - 23,477,577 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1522,549,108 - 23,474,504 (+)EnsemblGRCm39 Ensembl
GRCm381522,548,898 - 23,477,491 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1522,549,022 - 23,474,418 (+)EnsemblGRCm38mm10GRCm38
MGSCv371522,966,218 - 23,404,173 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361522,493,747 - 23,419,143 (+)NCBIMGSCv36mm8
MGSCv361522,612,245 - 23,539,922 (+)NCBIMGSCv36mm8
Celera1523,804,843 - 24,230,199 (+)NCBICelera
Cytogenetic Map15A2NCBI
cM Map158.54NCBI
Cdh18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8274,548,681 - 75,550,720 (+)NCBIGRCr8
mRatBN7.2272,818,076 - 73,820,144 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl273,345,005 - 73,820,138 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx280,511,705 - 80,989,073 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0278,634,250 - 79,111,614 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0273,662,502 - 74,139,875 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0273,651,408 - 74,693,342 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl274,360,622 - 74,693,341 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0294,092,755 - 94,420,560 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4274,531,500 - 74,727,208 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1274,391,226 - 74,712,229 (+)NCBI
Celera268,593,481 - 69,592,108 (+)NCBICelera
Cytogenetic Map2q22NCBI
Cdh18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554267,912,094 - 8,176,659 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554267,914,692 - 8,318,339 (-)NCBIChiLan1.0ChiLan1.0
CDH18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1483,915,145 - 84,873,581 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl484,417,872 - 84,870,827 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha483,556,973 - 84,421,117 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0484,540,567 - 85,505,464 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl485,046,653 - 85,502,673 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1484,059,834 - 85,022,511 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0484,313,153 - 85,268,917 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0485,092,626 - 86,117,931 (+)NCBIUU_Cfam_GSD_1.0
Cdh18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213212,509,277 - 213,072,533 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648021,443,797 - 21,897,514 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648021,444,839 - 21,897,520 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl168,098,686 - 8,578,235 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1168,090,253 - 9,117,046 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2168,744,658 - 9,051,039 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDH18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1418,981,462 - 19,337,792 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl418,983,427 - 19,337,822 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660648,930,784 - 9,470,405 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000058185   ⟹   ENSPPAP00000035297
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl596,163,304 - 96,531,116 (+)Ensembl
RefSeq Acc Id: XM_008971208   ⟹   XP_008969456
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2490,392,470 - 90,908,360 (+)NCBI
NHGRI_mPanPan1588,546,117 - 89,062,005 (+)NCBI
Mhudiblu_PPA_v0590,454,530 - 90,970,909 (+)NCBI
PanPan1.1596,014,735 - 96,533,064 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014344961   ⟹   XP_014200447
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2490,392,475 - 90,910,644 (+)NCBI
NHGRI_mPanPan1588,546,126 - 89,064,289 (+)NCBI
Mhudiblu_PPA_v0590,454,362 - 90,970,909 (+)NCBI
PanPan1.1596,014,735 - 96,530,880 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014344962   ⟹   XP_014200448
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2489,805,974 - 90,910,644 (+)NCBI
NHGRI_mPanPan1587,959,625 - 89,064,289 (+)NCBI
Mhudiblu_PPA_v0589,870,613 - 90,970,909 (+)NCBI
PanPan1.1595,432,743 - 96,533,064 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034960255   ⟹   XP_034816146
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2490,392,475 - 90,910,644 (+)NCBI
NHGRI_mPanPan1588,546,126 - 89,064,289 (+)NCBI
Mhudiblu_PPA_v0590,454,362 - 90,970,909 (+)NCBI
RefSeq Acc Id: XM_055112494   ⟹   XP_054968469
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2490,392,470 - 90,908,360 (+)NCBI
NHGRI_mPanPan1588,546,117 - 89,062,005 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_014200448   ⟸   XM_014344962
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C061 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008969456   ⟸   XM_008971208
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_014200447   ⟸   XM_014344961
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C061 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034816146   ⟸   XM_034960255
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C061 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000035297   ⟸   ENSPPAT00000058185
RefSeq Acc Id: XP_054968469   ⟸   XM_055112494
- Peptide Label: isoform X2
Protein Domains
Cadherin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040456 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000058185.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.900.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/TrEMBL
  Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  Cadherin_cytoplasmic-dom UniProtKB/TrEMBL
  Catenin-bd_sf UniProtKB/TrEMBL
KEGG Report pps:100977350 UniProtKB/TrEMBL
NCBI Gene CDH18 ENTREZGENE
PANTHER CADHERIN-18 UniProtKB/TrEMBL
  PTHR24027 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  Cadherin_C UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
SMART SM00112 UniProtKB/TrEMBL
Superfamily-SCOP SSF49313 UniProtKB/TrEMBL
UniProt A0A2R9C061 ENTREZGENE, UniProtKB/TrEMBL