SIM2 (SIM bHLH transcription factor 2) - Rat Genome Database

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Gene: SIM2 (SIM bHLH transcription factor 2) Pan paniscus
Analyze
Symbol: SIM2
Name: SIM bHLH transcription factor 2
RGD ID: 11909008
Description: ENCODES a protein that exhibits DNA binding (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN embryonic pattern specification (ortholog); lung development (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); autosomal dominant intellectual developmental disorder 7 (ortholog); cleft palate (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: single-minded family bHLH transcription factor 2; single-minded homolog 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22232,811,175 - 32,864,472 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12127,671,481 - 27,720,202 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02123,060,640 - 23,109,496 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12136,415,945 - 36,462,339 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nuclear body  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SIM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22232,811,175 - 32,864,472 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12127,671,481 - 27,720,202 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02123,060,640 - 23,109,496 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12136,415,945 - 36,462,339 (+)NCBIpanpan1.1PanPan1.1panPan2
SIM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382136,699,115 - 36,749,917 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2136,699,115 - 36,749,917 (+)EnsemblGRCh38hg38GRCh38
GRCh372138,071,415 - 38,122,218 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,993,861 - 37,044,088 (+)NCBINCBI36Build 36hg18NCBI36
Build 342136,993,860 - 37,040,483NCBI
Celera2123,270,361 - 23,320,891 (+)NCBICelera
Cytogenetic Map21q22.13ENTREZGENE
HuRef2123,547,929 - 23,598,327 (+)NCBIHuRef
CHM1_12137,633,195 - 37,683,684 (+)NCBICHM1_1
T2T-CHM13v2.02135,081,302 - 35,132,110 (+)NCBIT2T-CHM13v2.0
Sim2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391693,885,963 - 93,927,891 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1693,885,790 - 93,927,891 (+)EnsemblGRCm39 Ensembl
GRCm381694,085,104 - 94,127,032 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1694,084,931 - 94,127,032 (+)EnsemblGRCm38mm10GRCm38
MGSCv371694,085,505 - 94,348,638 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361693,973,471 - 94,236,925 (+)NCBIMGSCv36mm8
Celera1695,171,465 - 95,213,526 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1655.05NCBI
Sim2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81146,883,859 - 46,923,305 (+)NCBIGRCr8
mRatBN7.21133,414,218 - 33,453,663 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,414,218 - 33,453,663 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1142,068,577 - 42,108,000 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01134,739,947 - 34,779,371 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01133,888,780 - 33,928,229 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01134,315,739 - 34,355,183 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1134,316,295 - 34,354,027 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01137,902,943 - 37,942,470 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41134,335,645 - 34,376,925 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11134,392,956 - 34,432,046 (+)NCBI
Celera1134,996,179 - 35,035,627 (-)NCBICelera
Cytogenetic Map11q11NCBI
Sim2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540735,828,250 - 35,867,620 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540735,828,250 - 35,869,067 (+)NCBIChiLan1.0ChiLan1.0
SIM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13131,879,483 - 31,929,531 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3131,879,360 - 31,930,359 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3130,940,849 - 30,994,549 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03131,182,551 - 31,236,268 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3131,182,291 - 31,234,643 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13131,050,827 - 31,104,585 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03131,063,591 - 31,118,290 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03131,553,961 - 31,607,783 (+)NCBIUU_Cfam_GSD_1.0
SIM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13200,355,407 - 200,403,247 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113200,354,963 - 200,408,890 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213210,439,397 - 210,483,094 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SIM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1280,680,061 - 80,730,331 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl280,680,678 - 80,725,951 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660548,522,886 - 8,570,977 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sim2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474526,852,980 - 26,891,176 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474526,851,423 - 26,891,590 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034947984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_034947984   ⟹   XP_034803875
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22232,811,175 - 32,864,472 (+)NCBI
NHGRI_mPanPan12127,671,481 - 27,720,202 (+)NCBI
Mhudiblu_PPA_v02123,060,640 - 23,109,496 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034803875 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_034803875   ⟸   XM_034947984


Additional Information

Database Acc Id Source(s)
NCBI Gene SIM2 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-04-24 SIM2  SIM bHLH transcription factor 2    single-minded family bHLH transcription factor 2  Symbol and/or name change 5135510 APPROVED