PGLYRP2 (peptidoglycan recognition protein 2) - Rat Genome Database

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Gene: PGLYRP2 (peptidoglycan recognition protein 2) Pan paniscus
Analyze
Symbol: PGLYRP2
Name: peptidoglycan recognition protein 2
RGD ID: 11905976
Description: ENCODES a protein that exhibits N-acetylmuramoyl-L-alanine amidase activity (inferred); peptidoglycan binding (inferred); peptidoglycan immune receptor activity (inferred); INVOLVED IN biological process involved in interaction with host (ortholog); negative regulation of natural killer cell differentiation involved in immune response (ortholog); negative regulation of type II interferon production (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: N-acetylmuramoyl-L-alanine amidase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22020,378,029 - 20,396,483 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11919,380,830 - 19,399,218 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,999,893 - 15,012,376 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,986,083 - 15,997,726 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,986,090 - 15,997,726 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PGLYRP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22020,378,029 - 20,396,483 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11919,380,830 - 19,399,218 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,999,893 - 15,012,376 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,986,083 - 15,997,726 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,986,090 - 15,997,726 (-)Ensemblpanpan1.1panPan2
PGLYRP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381915,468,645 - 15,479,501 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1915,468,645 - 15,498,956 (-)EnsemblGRCh38hg38GRCh38
GRCh371915,579,456 - 15,590,312 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,440,456 - 15,451,315 (-)NCBINCBI36Build 36hg18NCBI36
Build 341915,440,462 - 15,451,312NCBI
Celera1915,476,268 - 15,487,143 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1915,147,207 - 15,158,066 (-)NCBIHuRef
CHM1_11915,579,067 - 15,589,927 (-)NCBICHM1_1
T2T-CHM13v2.01915,593,641 - 15,604,523 (-)NCBIT2T-CHM13v2.0
Pglyrp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391732,631,433 - 32,643,157 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1732,631,433 - 32,643,141 (-)EnsemblGRCm39 Ensembl
GRCm381732,412,459 - 32,424,219 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1732,412,459 - 32,424,167 (-)EnsemblGRCm38mm10GRCm38
MGSCv371732,550,045 - 32,557,920 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361732,550,306 - 32,561,112 (-)NCBIMGSCv36mm8
Celera1733,325,622 - 33,333,482 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.56NCBI
Pglyrp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8712,069,414 - 12,082,437 (-)NCBIGRCr8
mRatBN7.2711,418,674 - 11,432,162 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl711,418,880 - 11,427,773 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx714,237,304 - 14,246,286 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0716,114,726 - 16,123,712 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,986,312 - 13,995,267 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0714,426,481 - 14,435,987 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl714,429,701 - 14,435,967 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,580,379 - 14,588,764 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,995,858 - 12,996,949 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera79,530,143 - 9,537,285 (-)NCBICelera
Cytogenetic Map7q11NCBI
Pglyrp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554957,785,193 - 7,796,210 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554957,785,398 - 7,792,158 (+)NCBIChiLan1.0ChiLan1.0
PGLYRP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12046,724,906 - 46,730,227 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2046,726,224 - 46,730,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,572,665 - 46,577,974 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02047,211,739 - 47,217,048 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2047,210,950 - 47,217,128 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12046,446,615 - 46,451,923 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02046,863,271 - 46,868,579 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,136,764 - 47,142,073 (+)NCBIUU_Cfam_GSD_1.0
Pglyrp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118205,489,000 - 205,495,525 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365965,038,452 - 5,044,569 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365965,038,452 - 5,043,172 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGLYRP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl262,134,533 - 62,140,184 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1262,135,578 - 62,140,180 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2261,567,649 - 61,572,250 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PGLYRP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1614,072,310 - 14,084,014 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl614,072,423 - 14,082,798 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660745,424,409 - 5,435,504 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pglyrp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249012,554,048 - 2,561,826 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249012,554,303 - 2,562,436 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000044951   ⟹   ENSPPAP00000022144
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,986,090 - 15,997,726 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044960   ⟹   ENSPPAP00000022153
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,986,808 - 15,997,245 (-)Ensembl
RefSeq Acc Id: XM_008966107   ⟹   XP_008964355
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22020,378,029 - 20,396,483 (-)NCBI
NHGRI_mPanPan11919,380,830 - 19,399,218 (-)NCBI
Mhudiblu_PPA_v01914,999,893 - 15,012,376 (-)NCBI
PanPan1.11915,986,083 - 15,997,726 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034945126   ⟹   XP_034801017
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22020,378,029 - 20,396,483 (-)NCBI
NHGRI_mPanPan11919,380,830 - 19,399,218 (-)NCBI
Mhudiblu_PPA_v01914,999,893 - 15,012,376 (-)NCBI
RefSeq Acc Id: XM_055103319   ⟹   XP_054959294
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22020,378,029 - 20,392,409 (-)NCBI
NHGRI_mPanPan11919,380,830 - 19,395,147 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008964355 (Get FASTA)   NCBI Sequence Viewer  
  XP_034801017 (Get FASTA)   NCBI Sequence Viewer  
  XP_054959294 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000022144
  ENSPPAP00000022144.1
  ENSPPAP00000022153.1
RefSeq Acc Id: XP_008964355   ⟸   XM_008966107
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AXV5 (UniProtKB/TrEMBL),   A0A2R9AYJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034801017   ⟸   XM_034945126
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AYJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000022144   ⟸   ENSPPAT00000044951
RefSeq Acc Id: ENSPPAP00000022153   ⟸   ENSPPAT00000044960
RefSeq Acc Id: XP_054959294   ⟸   XM_055103319
- Peptide Label: isoform X2

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034272 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000044951.1 UniProtKB/TrEMBL
  ENSPPAT00000044960.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.80.10 UniProtKB/TrEMBL
InterPro Amidase/PGRP_sf UniProtKB/TrEMBL
  Amidase_domain UniProtKB/TrEMBL
  PGRP UniProtKB/TrEMBL
  PGRP_domain_met/bac UniProtKB/TrEMBL
KEGG Report pps:100971889 UniProtKB/TrEMBL
NCBI Gene PGLYRP2 ENTREZGENE
PANTHER N-ACETYLMURAMOYL-L-ALANINE AMIDASE UniProtKB/TrEMBL
  PTHR11022 UniProtKB/TrEMBL
Pfam Amidase_2 UniProtKB/TrEMBL
SMART Ami_2 UniProtKB/TrEMBL
  PGRP UniProtKB/TrEMBL
Superfamily-SCOP SSF55846 UniProtKB/TrEMBL
UniProt A0A2R9AXV5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AYJ6 ENTREZGENE, UniProtKB/TrEMBL