NMRK2 (nicotinamide riboside kinase 2) - Rat Genome Database

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Gene: NMRK2 (nicotinamide riboside kinase 2) Pan paniscus
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Symbol: NMRK2
Name: nicotinamide riboside kinase 2
RGD ID: 11903729
Description: ENCODES a protein that exhibits ribosylnicotinamide kinase activity (ortholog); ribosylnicotinate kinase activity (ortholog); INVOLVED IN negative regulation of myoblast differentiation (inferred); nucleotide metabolic process (inferred); PARTICIPATES IN nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH amenorrhea (ortholog); RASopathy (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,330,887 - 8,341,144 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,562,513 - 7,573,013 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0192,958,503 - 2,967,246 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,909,663 - 3,914,572 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
amenorrhea  (ISO)
RASopathy  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NMRK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,330,887 - 8,341,144 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,562,513 - 7,573,013 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0192,958,503 - 2,967,246 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,909,663 - 3,914,572 (+)NCBIpanpan1.1PanPan1.1panPan2
NMRK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,933,069 - 3,942,416 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl193,933,069 - 3,942,416 (+)EnsemblGRCh38hg38GRCh38
GRCh37193,933,067 - 3,942,414 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,884,101 - 3,893,414 (+)NCBINCBI36Build 36hg18NCBI36
Build 34193,884,596 - 3,893,412NCBI
Celera193,870,565 - 3,879,557 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef193,696,838 - 3,706,107 (+)NCBIHuRef
CHM1_1193,932,706 - 3,942,091 (+)NCBICHM1_1
T2T-CHM13v2.0193,912,360 - 3,921,653 (+)NCBIT2T-CHM13v2.0
Nmrk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,034,004 - 81,037,871 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1081,034,004 - 81,037,885 (-)EnsemblGRCm39 Ensembl
GRCm381081,198,170 - 81,202,265 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,198,170 - 81,202,051 (-)EnsemblGRCm38mm10GRCm38
MGSCv371080,660,915 - 80,664,782 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361080,601,298 - 80,605,180 (-)NCBIMGSCv36mm8
Celera1082,218,526 - 82,222,393 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Nmrk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,165,567 - 9,168,638 (+)NCBIGRCr8
mRatBN7.278,514,855 - 8,517,916 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,514,927 - 8,517,922 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0711,382,966 - 11,386,170 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,383,116 - 11,386,948 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,550,492 - 11,553,583 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera76,702,775 - 6,705,979 (+)NCBICelera
Cytogenetic Map7q11NCBI
Nmrk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,749,309 - 5,756,367 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,749,303 - 5,754,889 (+)NCBIChiLan1.0ChiLan1.0
Nmrk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,600,207 - 215,605,292 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,231,269 - 2,234,412 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,229,869 - 2,234,573 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NMRK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,785,907 - 74,791,155 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,786,642 - 74,791,317 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,331,570 - 75,336,210 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NMRK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,685,337 - 3,697,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl63,688,166 - 3,697,960 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660814,552,214 - 4,561,116 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nmrk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248286,501,212 - 6,506,339 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248286,501,057 - 6,506,182 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_034945597   ⟹   XP_034801488
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2208,330,889 - 8,341,144 (+)NCBI
NHGRI_mPanPan1197,562,515 - 7,573,013 (+)NCBI
Mhudiblu_PPA_v0192,958,506 - 2,967,246 (+)NCBI
RefSeq Acc Id: XM_034945598   ⟹   XP_034801489
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2208,331,203 - 8,341,144 (+)NCBI
NHGRI_mPanPan1197,562,826 - 7,573,013 (+)NCBI
Mhudiblu_PPA_v0192,958,816 - 2,967,246 (+)NCBI
RefSeq Acc Id: XM_034945599   ⟹   XP_034801490
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2208,330,887 - 8,341,144 (+)NCBI
NHGRI_mPanPan1197,562,513 - 7,573,013 (+)NCBI
Mhudiblu_PPA_v0192,958,503 - 2,967,246 (+)NCBI
RefSeq Acc Id: XM_034945600   ⟹   XP_034801491
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2208,330,889 - 8,341,144 (+)NCBI
NHGRI_mPanPan1197,562,514 - 7,573,013 (+)NCBI
Mhudiblu_PPA_v0192,958,504 - 2,967,246 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034801488 (Get FASTA)   NCBI Sequence Viewer  
  XP_034801489 (Get FASTA)   NCBI Sequence Viewer  
  XP_034801490 (Get FASTA)   NCBI Sequence Viewer  
  XP_034801491 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000041432.1
RefSeq Acc Id: XP_034801490   ⟸   XM_034945599
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CR68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034801491   ⟸   XM_034945600
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034801488   ⟸   XM_034945597
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CR68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034801489   ⟸   XM_034945598
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CR68 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043330 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064358.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene NMRK2 ENTREZGENE
PANTHER URIDINE KINASE UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9CR68 ENTREZGENE, UniProtKB/TrEMBL