PKN3 (protein kinase N3) - Rat Genome Database

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Gene: PKN3 (protein kinase N3) Pan paniscus
Analyze
Symbol: PKN3
Name: protein kinase N3
RGD ID: 11900540
Description: ENCODES a protein that exhibits ATP binding (inferred); diacylglycerol-dependent serine/threonine kinase activity (inferred); protein kinase activity (inferred); INVOLVED IN epithelial cell migration (inferred); signal transduction (inferred); ASSOCIATED WITH genetic disease (ortholog); primary coenzyme Q10 deficiency 7 (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase N3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,629,789 - 10,648,482 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,632,138 - 10,653,781 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,825,546 - 99,844,582 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,492,598 - 128,510,790 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,493,251 - 128,510,476 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PKN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,629,789 - 10,648,482 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,632,138 - 10,653,781 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,825,546 - 99,844,582 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,492,598 - 128,510,790 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,493,251 - 128,510,476 (+)Ensemblpanpan1.1panPan2
PKN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,702,503 - 128,720,916 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,702,503 - 128,720,916 (+)EnsemblGRCh38hg38GRCh38
GRCh379131,464,782 - 131,483,195 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,504,623 - 130,523,020 (+)NCBINCBI36Build 36hg18NCBI36
Build 349128,544,355 - 128,562,752NCBI
Celera9102,115,606 - 102,133,985 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,074,402 - 101,092,860 (+)NCBIHuRef
CHM1_19131,615,771 - 131,634,165 (+)NCBICHM1_1
T2T-CHM13v2.09140,907,265 - 140,925,683 (+)NCBIT2T-CHM13v2.0
Pkn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39229,967,657 - 29,981,031 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl229,967,696 - 29,981,034 (+)EnsemblGRCm39 Ensembl
GRCm38230,077,548 - 30,091,023 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,077,684 - 30,091,022 (+)EnsemblGRCm38mm10GRCm38
MGSCv37229,934,286 - 29,946,539 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36229,900,775 - 29,913,028 (+)NCBIMGSCv36mm8
Celera229,782,278 - 29,794,536 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.13NCBI
Pkn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8333,747,610 - 33,761,405 (+)NCBIGRCr8
mRatBN7.2313,350,082 - 13,363,572 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,335,041 - 13,363,567 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx316,425,355 - 16,438,238 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,010,321 - 25,023,204 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,261,006 - 23,273,794 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,628,033 - 8,656,464 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,628,033 - 8,659,117 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0313,979,910 - 14,008,622 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,068,176 - 9,096,114 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.139,083,046 - 9,096,433 (+)NCBI
Celera38,109,358 - 8,136,810 (+)NCBICelera
Cytogenetic Map3p12NCBI
Pkn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,121,803 - 1,133,280 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555701,121,803 - 1,131,296 (+)NCBIChiLan1.0ChiLan1.0
PKN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,880,654 - 54,891,474 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,879,806 - 54,891,358 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,076,073 - 54,085,963 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0955,801,720 - 55,811,613 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,801,578 - 55,812,427 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,562,165 - 54,572,228 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,874,957 - 54,884,853 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,968,478 - 54,978,366 (-)NCBIUU_Cfam_GSD_1.0
Pkn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,421,900 - 196,432,822 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,190,519 - 16,203,858 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,191,953 - 16,201,349 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1269,070,512 - 269,081,334 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11269,069,088 - 269,081,334 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21303,092,940 - 303,105,193 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PKN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,423,039 - 9,440,783 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,423,354 - 9,440,463 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366609627,902 - 44,948 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pkn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247606,277,005 - 6,285,744 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247606,276,714 - 6,286,861 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000064505   ⟹   ENSPPAP00000041579
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9128,493,251 - 128,510,476 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000064508   ⟹   ENSPPAP00000041582
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9128,493,251 - 128,510,476 (+)Ensembl
RefSeq Acc Id: XM_034929211   ⟹   XP_034785102
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21110,629,789 - 10,648,482 (-)NCBI
NHGRI_mPanPan1910,632,138 - 10,653,778 (-)NCBI
Mhudiblu_PPA_v0999,825,549 - 99,844,582 (+)NCBI
RefSeq Acc Id: XM_034929212   ⟹   XP_034785103
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21110,630,223 - 10,648,482 (-)NCBI
NHGRI_mPanPan1910,632,138 - 10,653,781 (-)NCBI
Mhudiblu_PPA_v0999,825,546 - 99,844,148 (+)NCBI
RefSeq Acc Id: XM_055117144   ⟹   XP_054973119
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21110,629,789 - 10,648,416 (-)NCBI
NHGRI_mPanPan1910,632,138 - 10,650,372 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034785102 (Get FASTA)   NCBI Sequence Viewer  
  XP_034785103 (Get FASTA)   NCBI Sequence Viewer  
  XP_054973119 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000041579.1
  ENSPPAP00000041582.1
Reference Protein Sequences
RefSeq Acc Id: XP_034785103   ⟸   XM_034929212
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CRG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034785102   ⟸   XM_034929211
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CRG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000041582   ⟸   ENSPPAT00000064508
RefSeq Acc Id: ENSPPAP00000041579   ⟸   ENSPPAT00000064505
RefSeq Acc Id: XP_054973119   ⟸   XM_055117144
- Peptide Label: isoform X2
Protein Domains
AGC-kinase C-terminal   Protein kinase   REM-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043402 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064505.1 UniProtKB/TrEMBL
  ENSPPAT00000064508.1 UniProtKB/TrEMBL
Gene3D-CATH HR1 repeat UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  HR1_rho-bd UniProtKB/TrEMBL
  HR1_rpt_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
  PKN_HR1_1 UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene PKN3 ENTREZGENE
PANTHER PROTEIN KINASE C UniProtKB/TrEMBL
  RIBOSOMAL PROTEIN S6 KINASE UniProtKB/TrEMBL
Pfam HR1 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  REM_1 UniProtKB/TrEMBL
SMART Hr1 UniProtKB/TrEMBL
  S_TK_X UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF46585 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A2R9CI17_PANPA UniProtKB/TrEMBL
  A0A2R9CRG9 ENTREZGENE, UniProtKB/TrEMBL