CYP3A43 (cytochrome P450 family 3 subfamily A member 43) - Rat Genome Database

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Gene: CYP3A43 (cytochrome P450 family 3 subfamily A member 43) Pan paniscus
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Symbol: CYP3A43
Name: cytochrome P450 family 3 subfamily A member 43
RGD ID: 11894542
Description: ENCODES a protein that exhibits testosterone 16-alpha-hydroxylase activity (ortholog); testosterone 6-beta-hydroxylase activity (ortholog); INVOLVED IN oxidative demethylation (inferred); steroid metabolic process (inferred); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); nephrosis (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytochrome P450 3A43; LOC100979695
RGD Orthologs
Human
Rat
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26117,746,741 - 117,785,619 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,011,375 - 166,050,250 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0791,862,437 - 91,903,033 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,296,111 - 105,335,958 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,296,111 - 105,335,958 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CYP3A43
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26117,746,741 - 117,785,619 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,011,375 - 166,050,250 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0791,862,437 - 91,903,033 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,296,111 - 105,335,958 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,296,111 - 105,335,958 (+)Ensemblpanpan1.1panPan2
CYP3A43
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38799,828,013 - 99,866,093 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl799,828,013 - 99,866,093 (+)EnsemblGRCh38hg38GRCh38
GRCh37799,425,636 - 99,463,716 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,263,572 - 99,302,109 (+)NCBINCBI36Build 36hg18NCBI36
Build 34799,070,286 - 99,108,824NCBI
Celera794,159,885 - 94,198,421 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,061,564 - 94,099,614 (+)NCBIHuRef
CHM1_1799,355,683 - 99,393,889 (+)NCBICHM1_1
T2T-CHM13v2.07101,067,527 - 101,105,595 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2798,785,456 - 98,823,546 (+)NCBI
Cyp3a18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81213,994,312 - 14,044,185 (+)NCBIGRCr8
mRatBN7.2128,880,509 - 8,930,382 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,880,528 - 8,930,381 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx129,678,389 - 9,728,392 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01210,301,584 - 10,351,575 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,325,028 - 9,375,015 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01210,636,294 - 10,684,273 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1210,636,275 - 10,684,278 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01212,738,271 - 12,787,784 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,086,752 - 9,136,606 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,116,679 - 9,166,534 (-)NCBI
Celera1210,707,212 - 10,757,562 (+)NCBICelera
Cytogenetic Map12p11NCBI
CYP3A43
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12813,217,123 - 13,256,859 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2813,216,548 - 13,257,015 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,012,292 - 3,052,631 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000025107   ⟹   ENSPPAP00000005534
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7105,296,111 - 105,334,971 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000025117   ⟹   ENSPPAP00000005538
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7105,296,111 - 105,334,971 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000025134   ⟹   ENSPPAP00000005540
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7105,296,117 - 105,335,958 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000025147   ⟹   ENSPPAP00000005545
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7105,296,214 - 105,334,868 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000025150   ⟹   ENSPPAP00000005548
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7105,296,214 - 105,334,868 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000025152   ⟹   ENSPPAP00000005550
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7105,296,214 - 105,334,868 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000025153   ⟹   ENSPPAP00000005551
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7105,296,214 - 105,316,664 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000025163   ⟹   ENSPPAP00000005553
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7105,296,214 - 105,307,480 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000025168   ⟹   ENSPPAP00000005554
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7105,296,246 - 105,334,782 (+)Ensembl
RefSeq Acc Id: XM_003815721   ⟹   XP_003815769
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26117,746,741 - 117,785,619 (+)NCBI
NHGRI_mPanPan17166,011,375 - 166,050,250 (+)NCBI
Mhudiblu_PPA_v0791,862,476 - 91,901,539 (+)NCBI
PanPan1.17105,296,111 - 105,334,971 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008968741   ⟹   XP_008966989
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26117,746,741 - 117,785,619 (+)NCBI
NHGRI_mPanPan17166,011,375 - 166,050,250 (+)NCBI
Mhudiblu_PPA_v0791,862,476 - 91,902,770 (+)NCBI
PanPan1.17105,296,111 - 105,334,971 (+)NCBI
Sequence:
RefSeq Acc Id: XM_057302723   ⟹   XP_057158706
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26117,746,741 - 117,785,619 (+)NCBI
NHGRI_mPanPan17166,011,375 - 166,050,250 (+)NCBI
RefSeq Acc Id: XP_008966989   ⟸   XM_008968741
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZLS0 (UniProtKB/TrEMBL),   A0A2R8ZNI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003815769   ⟸   XM_003815721
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZNI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000005538   ⟸   ENSPPAT00000025117
RefSeq Acc Id: ENSPPAP00000005534   ⟸   ENSPPAT00000025107
RefSeq Acc Id: ENSPPAP00000005553   ⟸   ENSPPAT00000025163
RefSeq Acc Id: ENSPPAP00000005554   ⟸   ENSPPAT00000025168
RefSeq Acc Id: ENSPPAP00000005550   ⟸   ENSPPAT00000025152
RefSeq Acc Id: ENSPPAP00000005551   ⟸   ENSPPAT00000025153
RefSeq Acc Id: ENSPPAP00000005548   ⟸   ENSPPAT00000025150
RefSeq Acc Id: ENSPPAP00000005545   ⟸   ENSPPAT00000025147
RefSeq Acc Id: ENSPPAP00000005540   ⟸   ENSPPAT00000025134
RefSeq Acc Id: XP_057158706   ⟸   XM_057302723
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZKQ8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000022863 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000025107.1 UniProtKB/TrEMBL
  ENSPPAT00000025117.1 UniProtKB/TrEMBL
  ENSPPAT00000025134.1 UniProtKB/TrEMBL
  ENSPPAT00000025147.1 UniProtKB/TrEMBL
  ENSPPAT00000025150.1 UniProtKB/TrEMBL
  ENSPPAT00000025152.1 UniProtKB/TrEMBL
  ENSPPAT00000025153.1 UniProtKB/TrEMBL
  ENSPPAT00000025163.1 UniProtKB/TrEMBL
  ENSPPAT00000025168.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/TrEMBL
  Cyt_P450_E_CYP3A UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/TrEMBL
  Cyt_P450_E_grp-II UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/TrEMBL
NCBI Gene LOC100979695 ENTREZGENE
PANTHER CYTOCHROME P450 3A43 UniProtKB/TrEMBL
  CYTOCHROME P450 FAMILY 3 UniProtKB/TrEMBL
Pfam p450 UniProtKB/TrEMBL
PRINTS EP450I UniProtKB/TrEMBL
  EP450II UniProtKB/TrEMBL
  EP450IICYP3A UniProtKB/TrEMBL
  P450 UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/TrEMBL
UniProt A0A2R8ZKP7_PANPA UniProtKB/TrEMBL
  A0A2R8ZKQ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZKR2_PANPA UniProtKB/TrEMBL
  A0A2R8ZLS0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZLU2_PANPA UniProtKB/TrEMBL
  A0A2R8ZNI2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZNI7_PANPA UniProtKB/TrEMBL
  A0A2R8ZNJ1_PANPA UniProtKB/TrEMBL
  A0A2R8ZRT9_PANPA UniProtKB/TrEMBL
VGNC ID VGNC:83026 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-25 CYP3A43  cytochrome P450 family 3 subfamily A member 43  LOC100979695  cytochrome P450 3A43  Symbol and/or name change 5135510 APPROVED