TRIM25 (tripartite motif containing 25) - Rat Genome Database

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Gene: TRIM25 (tripartite motif containing 25) Pan paniscus
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Symbol: TRIM25
Name: tripartite motif containing 25
RGD ID: 11891550
Description: ENCODES a protein that exhibits RIG-I binding (ortholog); transcription coactivator activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); innate immune response (ortholog); negative regulation of viral entry into host cell (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin/ISG15 ligase TRIM25
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11755,826,458 - 55,852,422 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1755,826,458 - 55,852,422 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01750,965,592 - 50,991,630 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
TRIM25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11755,826,458 - 55,852,422 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1755,826,458 - 55,852,422 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01750,965,592 - 50,991,630 (-)NCBIMhudiblu_PPA_v0panPan3
TRIM25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1756,836,387 - 56,914,080 (-)EnsemblGRCh38hg38GRCh38
GRCh381756,887,909 - 56,914,049 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371754,965,270 - 54,991,410 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361752,320,269 - 52,346,408 (-)NCBINCBI36hg18NCBI36
Build 341752,323,634 - 52,346,408NCBI
Celera1751,426,842 - 51,452,985 (-)NCBI
Cytogenetic Map17q22NCBI
HuRef1750,325,845 - 50,351,990 (-)NCBIHuRef
CHM1_11755,030,515 - 55,056,657 (-)NCBICHM1_1
Trim25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391188,890,194 - 88,911,119 (+)NCBIGRCm39mm39
GRCm39 Ensembl1188,890,202 - 88,911,119 (+)Ensembl
GRCm381188,999,403 - 89,020,294 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1188,999,376 - 89,020,293 (+)EnsemblGRCm38mm10GRCm38
MGSCv371188,860,717 - 88,881,607 (+)NCBIGRCm37mm9NCBIm37
MGSCv361188,815,570 - 88,836,383 (+)NCBImm8
Celera1198,615,674 - 98,636,481 (+)NCBICelera
Cytogenetic Map11CNCBI
Trim25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21073,812,818 - 73,831,271 (+)NCBI
Rnor_6.0 Ensembl1076,343,847 - 76,362,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01076,343,847 - 76,362,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01073,750,003 - 73,769,423 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41077,459,844 - 77,488,383 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1072,717,934 - 72,735,695 (+)NCBICelera
Cytogenetic Map10q26NCBI
Trim25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554515,918,287 - 5,934,258 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554515,918,287 - 5,934,252 (+)NCBIChiLan1.0ChiLan1.0
TRIM25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1931,703,628 - 31,725,674 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl931,707,034 - 31,725,762 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha930,943,465 - 30,965,495 (-)NCBI
ROS_Cfam_1.0932,511,355 - 32,533,408 (-)NCBI
UMICH_Zoey_3.1931,296,490 - 31,318,526 (-)NCBI
UNSW_CanFamBas_1.0931,580,728 - 31,602,758 (-)NCBI
UU_Cfam_GSD_1.0931,664,093 - 31,686,131 (-)NCBI
Trim25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560231,081,655 - 31,095,879 (-)NCBI
SpeTri2.0NW_0049364905,979,320 - 5,997,632 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1233,184,044 - 33,212,398 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11233,184,039 - 33,212,440 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21234,134,354 - 34,153,408 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11636,496,829 - 36,522,427 (+)NCBI
ChlSab1.1 Ensembl1636,496,772 - 36,524,148 (+)Ensembl
Vero_WHO_p1.0NW_0236660777,316,204 - 7,343,303 (+)NCBI
Trim25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479511,967,908 - 11,986,707 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003817406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000041312   ⟹   ENSPPAP00000018579
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1755,826,458 - 55,852,422 (-)Ensembl
RefSeq Acc Id: XM_003817406   ⟹   XP_003817454
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11755,826,458 - 55,852,422 (-)NCBI
Mhudiblu_PPA_v01750,965,592 - 50,991,630 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003817454 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003817454   ⟸   XM_003817406
- Sequence:
RefSeq Acc Id: ENSPPAP00000018579   ⟸   ENSPPAT00000041312
Protein Domains
B30.2/SPRY   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032434 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000018579 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041312 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  TRIM25_SPRY_PRY UniProtKB/TrEMBL
  Znf-RING_LisH UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report pps:100971009 UniProtKB/TrEMBL
NCBI Gene TRIM25 ENTREZGENE
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART PRY UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
UniProt A0A2R9AUH9_PANPA UniProtKB/TrEMBL