PSMB1 (proteasome 20S subunit beta 1)

Gene: PSMB1 (proteasome 20S subunit beta 1) Pan paniscus

Analyze

Symbol:

PSMB1

Name:

proteasome 20S subunit beta 1

RGD ID:

11890221

Description:

INVOLVED IN proteolysis involved in protein catabolic process (inferred); ASSOCIATED WITH Acute Coronary Syndrome (ortholog); amenorrhea (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

proteasome (prosome, macropain) subunit, beta type, 1; proteasome subunit beta 1; proteasome subunit beta type-1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	190,812,047 - 190,831,109 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	188,713,683 - 188,732,729 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	168,695,047 - 168,713,257 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	173,781,040 - 173,799,243 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	173,781,040 - 173,799,342 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute Coronary Syndrome (ISO)

amenorrhea (ISO)

genetic disease (ISO)

NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, HYPOTONIA, AND ABSENT LANGUAGE (ISO)

osteoarthritis (ISO)

peripheral nervous system disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteolysis involved in protein catabolic process (IEA)

Cellular Component

cytoplasm (IEA,ISO)

nucleoplasm (IEA)

nucleus (IEA,ISO)

proteasome complex (IEA)

proteasome core complex (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

PSMB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	190,812,047 - 190,831,109 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	188,713,683 - 188,732,729 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	168,695,047 - 168,713,257 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	173,781,040 - 173,799,243 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	173,781,040 - 173,799,342 (-)	Ensembl	panpan1.1		panPan2

PSMB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	170,535,120 - 170,553,307 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	170,535,120 - 170,553,307 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	170,844,208 - 170,862,395 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	170,686,134 - 170,704,312 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	170,761,840 - 170,780,019	NCBI
Celera	6	171,639,464 - 171,657,679 (-)	NCBI		Celera
Cytogenetic Map	6	q27	NCBI
HuRef	6	168,349,261 - 168,367,473 (-)	NCBI		HuRef
CHM1_1	6	171,105,483 - 171,123,692 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	171,908,679 - 171,926,858 (-)	NCBI		T2T-CHM13v2.0

Psmb1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	15,695,983 - 15,718,538 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	15,695,283 - 15,720,013 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	15,475,721 - 15,498,276 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	15,475,021 - 15,499,751 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	15,612,685 - 15,635,240 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	15,180,922 - 15,203,243 (-)	NCBI		MGSCv36	mm8
Celera	17	16,263,619 - 16,283,553 (-)	NCBI		Celera
Cytogenetic Map	17	A2	NCBI
cM Map	17	8.95	NCBI

Psmb1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	65,115,770 - 65,136,516 (-)	NCBI		GRCr8
mRatBN7.2	1	56,442,432 - 56,463,544 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	56,420,618 - 56,463,560 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	61,293,207 - 61,311,018 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	69,956,748 - 69,974,559 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	63,203,175 - 63,220,987 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	57,470,878 - 57,491,359 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	57,470,632 - 57,489,727 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	58,399,237 - 58,419,917 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	54,369,775 - 54,388,816 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	54,372,719 - 54,391,761 (-)	NCBI
Celera	1	52,648,620 - 52,666,985 (-)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

Psmb1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	3,286,835 - 3,304,931 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	3,285,610 - 3,304,210 (+)	NCBI	ChiLan1.0	ChiLan1.0

PSMB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	72,440,224 - 72,456,304 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	72,440,224 - 72,456,284 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	72,202,460 - 72,218,544 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	73,425,690 - 73,441,776 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	73,425,690 - 73,441,754 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	72,698,433 - 72,714,512 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	72,520,615 - 72,536,698 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	72,911,637 - 72,927,722 (-)	NCBI		UU_Cfam_GSD_1.0

Psmb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	151,224,293 - 151,246,522 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004937098	66,832 - 81,708 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004937098	67,298 - 80,019 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSMB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	23,676 - 40,032 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	23,827 - 40,033 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PSMB1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	97,682,501 - 97,701,339 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	97,682,369 - 97,701,799 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	69,680,366 - 69,699,217 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psmb1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624850	6,337,094 - 6,357,997 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624850	6,339,918 - 6,357,925 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003821662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000057193 ⟹ ENSPPAP00000034312

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	6	173,781,040 - 173,799,342 (-)	Ensembl

RefSeq Acc Id:

XM_003821662 ⟹ XP_003821710

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	5	190,812,047 - 190,831,109 (-)	NCBI
NHGRI_mPanPan1	6	188,713,683 - 188,732,729 (-)	NCBI
Mhudiblu_PPA_v0	6	168,695,047 - 168,713,257 (-)	NCBI
PanPan1.1	6	173,781,040 - 173,799,243 (-)	NCBI

Sequence:

show sequence

ACTTCAGGAGAAGCCGGAAGTGGCGTAACGTCCGGTCAAGGCAGCCATCTCGCCGTGAGACAGC
AAGTGTCGGATCCGCAGGCGCAGCCGTGCGATGTTGTCCTCTACAGCCATGTATTCGGCTCCTG
GCAGAGACTTGGGGATGGAACCGCACAGAGCCGCGGGCCCTTTGCAGCTGCGATTTTCGCCCTA
CGTTTTCAACGGAGGTACTATACTGGCAATTGCTGGAGAAGATTTTGCAATTGTTGCTTCTGAT
ACTCGATTGAGTGAAGGGTTTTCAATTCATACGCGGGATAGCCCCAAATGTTACAAATTAACAG
ACAAAACAGTCATTGGATGCAGTGGTTTTCATGGAGACTGCCTTACGCTGACAAAGATTATTGA
AGCAAGACTAAAGATGTATAAGCATTCCAATAATAAGGCCATGACTACGGGGGCAATTGCTGCA
ATGCTGTCTACAATCCTGTATTCAAGGCGCTTCTTTCCATACTATGTTTACAACATCATCGGTG
GACTTGATGAAGAAGGAAAGGGGGCTGTATACAGCTTTGATCCAGTAGGGTCTTACCAGAGAGA
CTCCTTCAAGGCTGGAGGCTCAGCAAGTGCCATGCTACAGCCCCTGCTTGACAACCAGGTTGGT
TTTAAGAACATGCAGAATGTGGAGCATGTTCCGCTGTCCTTGGACAGAGCCATGCGGCTGGTGA
AAGATGTCTTCATTTCTGCGGCTGAGAGAGATGTGTACACTGGGGACGCACTCCGGATCTGCAT
AGTGACCAAAGAGGGCATCAGGGAGGAGACTGTTTCCTTAAGGAAGGACTGATCTGTGTGCTCT
TATCACCAATCAGTTCAGAACTGGTTGATTTTGTACTTTGGAACTGTACCTTGGATGGTTTTGT
TTATTAAAAGAGAAACCTGAAGTACTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003821710	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000034312
	ENSPPAP00000034312.1

RefSeq Acc Id:

XP_003821710 ⟸ XM_003821662

- UniProtKB:

A0A2R9BX98 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIH
TRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRR
FFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHV
PLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD

hide sequence

RefSeq Acc Id:

ENSPPAP00000034312 ⟸ ENSPPAT00000057193

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000039999	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000057193.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.20.10	UniProtKB/TrEMBL
InterPro	Ntn_hydrolases_N	UniProtKB/TrEMBL
	Proteasome_bsu_CS	UniProtKB/TrEMBL
	Proteasome_sua/b	UniProtKB/TrEMBL
	Proteasome_suB-type	UniProtKB/TrEMBL
KEGG Report	pps:100977823	UniProtKB/TrEMBL
NCBI Gene	PSMB1	ENTREZGENE
PANTHER	METALLOPROTEASE TLDD	UniProtKB/TrEMBL
	PROTEASOME SUBUNIT BETA TYPE-1	UniProtKB/TrEMBL
Pfam	Proteasome	UniProtKB/TrEMBL
PROSITE	PROTEASOME_BETA_1	UniProtKB/TrEMBL
	PROTEASOME_BETA_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56235	UniProtKB/TrEMBL
UniProt	A0A2R9BX98	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-09-03	PSMB1	proteasome 20S subunit beta 1	PSMB1	proteasome subunit beta 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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