KRT16 (keratin 16) - Rat Genome Database

Name: KRT16
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: KRT16 (keratin 16) Pan paniscus

Analyze

Symbol:

KRT16

Name:

keratin 16

RGD ID:

11887090

Description:

ENCODES a protein that exhibits structural constituent of cytoskeleton (ortholog); INVOLVED IN cytoskeleton organization (ortholog); establishment of skin barrier (ortholog); inflammatory response (ortholog); ASSOCIATED WITH ectodermal dysplasia (ortholog); epidermolytic palmoplantar keratoderma (ortholog); esophagus squamous cell carcinoma (ortholog); FOUND IN cornified envelope (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

keratin, type I cytoskeletal 16

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	23,372,263 - 23,375,369 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	25,262,534 - 25,265,531 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	15,704,348 - 15,707,328 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	15,922,924 - 15,925,956 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	15,922,924 - 15,929,437 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ectodermal dysplasia (ISO)

epidermolytic palmoplantar keratoderma (ISO)

esophagus squamous cell carcinoma (ISO)

focal nonepidermolytic palmoplantar keratoderma (ISO)

focal nonepidermolytic palmoplantar keratoderma 1 (ISO)

genetic disease (ISO)

nonepidermolytic palmoplantar keratoderma (ISO)

pachyonychia congenita (ISO)

Pachyonychia Congenita 1 (ISO)

urinary bladder cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytoskeleton organization (ISO)

epithelial cell differentiation (IEA)

establishment of skin barrier (ISO)

hair cycle (IEA)

inflammatory response (ISO)

innate immune response (ISO)

intermediate filament cytoskeleton organization (ISO)

intermediate filament organization (IEA)

keratinization (ISO)

keratinocyte differentiation (ISO)

keratinocyte migration (ISO)

morphogenesis of an epithelium (ISO)

negative regulation of cell migration (IEA)

Cellular Component

cornified envelope (ISO)

cytoskeleton (IEA)

intermediate filament (IEA)

keratin filament (IEA)

Molecular Function

protein binding (ISO)

structural constituent of cytoskeleton (ISO)

structural molecule activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

KRT16
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	23,372,263 - 23,375,369 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	25,262,534 - 25,265,531 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	15,704,348 - 15,707,328 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	15,922,924 - 15,925,956 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	15,922,924 - 15,929,437 (+)	Ensembl	panpan1.1		panPan2

KRT16
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	41,609,778 - 41,612,767 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	41,609,778 - 41,615,899 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	39,766,030 - 39,769,019 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	37,019,556 - 37,022,545 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	37,019,558 - 37,022,545	NCBI
Celera	17	36,419,179 - 36,422,228 (-)	NCBI		Celera
Cytogenetic Map	17	q21.2	NCBI
HuRef	17	35,529,076 - 35,532,125 (-)	NCBI		HuRef
CHM1_1	17	40,001,344 - 40,004,393 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	42,465,231 - 42,468,220 (-)	NCBI		T2T-CHM13v2.0

Krt16
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	100,136,917 - 100,139,728 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	100,136,917 - 100,139,728 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	100,246,091 - 100,248,902 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	100,246,091 - 100,248,902 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	100,107,405 - 100,110,216 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	100,062,181 - 100,064,992 (-)	NCBI		MGSCv36	mm8
Celera	11	110,863,405 - 110,866,216 (-)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	63.44	NCBI

Krt16
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	85,669,276 - 85,672,211 (-)	NCBI		GRCr8
mRatBN7.2	10	85,168,357 - 85,171,816 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	85,066,802 - 85,171,799 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	90,209,480 - 90,212,279 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	89,685,401 - 89,688,120 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	85,077,325 - 85,080,044 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	88,149,210 - 88,152,167 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	88,149,345 - 88,152,064 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	87,942,554 - 87,945,393 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	89,175,449 - 89,178,168 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	83,888,355 - 83,891,074 (-)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

KRT16
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	64,629,385 - 64,633,125 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	64,630,042 - 64,633,114 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	35,473,886 - 35,477,089 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003813843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063599051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000050753 ⟹ ENSPPAP00000027910

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	15,922,924 - 15,925,956 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000050755 ⟹ ENSPPAP00000027912

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	15,923,057 - 15,929,437 (+)	Ensembl

RefSeq Acc Id:

XM_003813843 ⟹ XP_003813891

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	19	23,372,263 - 23,375,369 (+)	NCBI
NHGRI_mPanPan1	17	25,262,534 - 25,265,531 (+)	NCBI
Mhudiblu_PPA_v0	17	15,704,348 - 15,707,328 (+)	NCBI
PanPan1.1	17	15,922,924 - 15,925,956 (+)	NCBI

Sequence:

show sequence

GAGGGCCCCGCCTTCCCCAGGTGCATATAAAGGTCTCTGGGGTTGGAGGCAGCCACAGCACGCT
CTCAGCCTTCCTGAGCACCTTTCCTTCTTTCAGCCAACTGCTCACTCGCTCACCTCCCTCCTTG
GCACCATGACCACCTGCAGCCGCCAGTTCACCTCCTCCAGCTCCATGAAGGGCTCCTGCGGCAT
TGGGGGCGGCTCCAGCCGCATCTCCTCCGTCCTGGCCGGAGGGTCCTGCCGTGCCCCCAGCACC
TACGGGGGCGGCCTGTCTGTCTCCTCTCGCTTCTCCTCTGGGGGAGCCTGCGGGCTGGGGGGCG
GCTATGGTGGTGGCTTCAGCAGCAGCAGCAGCTTTGGTAGTGGCTTCGGGGGAGGATATGGTGG
TGGCCTTGGTGCTGGCTTCGGTGGTGGCTTGGGTGCTGGCTTTGGTGGTGGTTTTGCTGGTGGT
GATGGGCTTCTGGTGGGCAGTGAGAAGGTGACCATGCAGAACCTCAACGACCGCCTGGCCTCCT
ACCTGGACAAGGTGCGTGCTCTGGAGGAGGCCAACGCTGACCTGGAAGTGAAGATCCGTGACTG
GTACCAGAGGCAGCGGCCTGCTGAGATCAAAGACTACAGTCCCTACTTCAAGACCATCGAGGAC
CTGAGGAACAAGATCATTGCGGCCACCATTGAGAATGCACAGCCCATTTTGCAGATTGACAATG
CCAGGCTGGCAGCCGATGACTTCAGGACCAAGTATGAGCACGAACTGGCCCTGCGGCAGACTGT
GGAGGCCGACGTCAATGGCCTGCGCCGGGTGTTGGATGAGCTGACCCTGGCCAGGACTGACCTG
GAGATGCAGATTGAAGGCCTGAAGGAGGAGCTGGCCTACCTGAGGAAGAATCACGAGGAGGAGA
TGCTTGCTCTGAGAGGTCAGACCGGCGGAGATGTGAACGTGGAGATGGATGCTGCACCTGGCGT
GGACCTGAGCCGCATCCTGAATGAGATGCGTGACCAGTACGAGCAGATGGCAGAGAAAAACCGC
AGAGACGCTGAGGCCTGGTTCCTGAGCAAGACCGAGGAGCTGAACAAAGAAGTGGCCTCCAACA
GCGAACTGGTACAGAGCAGCCGCAGTGAGGTGACGGAGCTCCGGAGGGTGCTCCAGGGCCTGGA
GATTGAGCTGCAGTCCCAGCTCAGCATGAAAGCATCCCTGGAGAACAGCCTGGAGGAGACCAAA
GGCCGCTACTGCATGCAGCTGTCCCAGATCCAGGGACTGATTGGCAGTGTGGAGGAGCAGCTGG
CCCAGCTACGCTGTGAGATGGAGCAGCAGAGCCAGGAGTACCAGATCTTGCTGGATGTGAAGAC
GCGGCTGGAGCAGGAGATCGCCACCTACCGCCGCCTGCTGGAGGGCGAGGATGCCCACCTTTCC
TCCCAGCAAGCATCTGGCCAATCCTATTCTTCCCGCGAGGTCTTCACCTCCTCCTCGTCCTCTT
CGAGCCGTCAGACCCGGCCCATCCTCAAGGAGCAGAGCTCATCCAGCTTCAGCCAGGGCCAGAG
CTCCTAGAACTGAGCTGCCTCTACCACAGCCTCCTGCCCACCAGCTGGCCTCACCTCCTGAAGG
CCGGGGTCAGGACCCTGCTCTCCTGGCGCAGTTCCCAGCTATCTCCCCTGCTCCTCTGCTGGTG
GTGGGCTAATAAAGCTGACTTTCTGGTTGATGCAAA

hide sequence

RefSeq Acc Id:

XM_063599051 ⟹ XP_063455121

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	19	23,372,263 - 23,375,298 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003813891	(Get FASTA)	NCBI Sequence Viewer
	XP_063455121	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000027910
	ENSPPAP00000027910.1
	ENSPPAP00000027912.1

RefSeq Acc Id:	XP_003813891 ⟸ XM_003813843
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BE51 (UniProtKB/TrEMBL), A0A2R9BI07 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTTCSRQFTSSSSMKGSCGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGY GGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYL DKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNAR LAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEML ALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAEAWFLSKTEELNKEVASNSE LVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQ LRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQASGQSYSSREVFTSSSSSSS RQTRPILKEQSSSSFSQGQSS hide sequence

RefSeq Acc Id:

ENSPPAP00000027912 ⟸ ENSPPAT00000050755

RefSeq Acc Id:

ENSPPAP00000027910 ⟸ ENSPPAT00000050753

RefSeq Acc Id:	XP_063455121 ⟸ XM_063599051
- Peptide Label:	isoform X2

Protein Domains

IF rod

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000037025	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000050753.1	UniProtKB/TrEMBL
	ENSPPAT00000050755.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.170	UniProtKB/TrEMBL
	Single helix bin	UniProtKB/TrEMBL
	Vasodilator-stimulated phosphoprotein	UniProtKB/TrEMBL
InterPro	IF_conserved	UniProtKB/TrEMBL
	IF_rod_dom	UniProtKB/TrEMBL
	Keratin_I	UniProtKB/TrEMBL
KEGG Report	pps:100976769	UniProtKB/TrEMBL
NCBI Gene	KRT16	ENTREZGENE
PANTHER	KERATIN, TYPE I CYTOSKELETAL 16	UniProtKB/TrEMBL
	PTHR23239	UniProtKB/TrEMBL
Pfam	Filament	UniProtKB/TrEMBL
PRINTS	TYPE1KERATIN	UniProtKB/TrEMBL
PROSITE	IF_ROD_1	UniProtKB/TrEMBL
	IF_ROD_2	UniProtKB/TrEMBL
SMART	Filament	UniProtKB/TrEMBL
Superfamily-SCOP	Intermediate filament protein, coiled coil region	UniProtKB/TrEMBL
UniProt	A0A2R9BE51	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BI07	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI

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