TRIM35 (tripartite motif containing 35) - Rat Genome Database

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Gene: TRIM35 (tripartite motif containing 35) Pan paniscus
Analyze
Symbol: TRIM35
Name: tripartite motif containing 35
RGD ID: 11886600
Description: ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN myeloid cell apoptotic process (ortholog); negative regulation of cell population proliferation (ortholog); positive regulation of myeloid cell apoptotic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase TRIM35; tripartite motif-containing protein 35
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2745,814,684 - 45,841,408 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1821,528,894 - 21,555,414 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0826,554,217 - 26,580,684 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1823,757,009 - 23,783,457 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl823,757,009 - 23,783,457 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRIM35
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2745,814,684 - 45,841,408 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1821,528,894 - 21,555,414 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0826,554,217 - 26,580,684 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1823,757,009 - 23,783,457 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl823,757,009 - 23,783,457 (-)Ensemblpanpan1.1panPan2
TRIM35
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38827,284,886 - 27,311,272 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl827,284,886 - 27,311,272 (-)EnsemblGRCh38hg38GRCh38
GRCh37827,142,403 - 27,168,789 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36827,198,321 - 27,224,751 (-)NCBINCBI36Build 36hg18NCBI36
Build 34827,198,320 - 27,224,751NCBI
Celera826,105,312 - 26,131,742 (-)NCBICelera
Cytogenetic Map8p21.2NCBI
HuRef825,687,527 - 25,713,958 (-)NCBIHuRef
CHM1_1827,344,328 - 27,370,758 (-)NCBICHM1_1
T2T-CHM13v2.0827,561,710 - 27,588,095 (-)NCBIT2T-CHM13v2.0
Trim35
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391466,534,474 - 66,548,873 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1466,534,480 - 66,548,873 (+)EnsemblGRCm39 Ensembl
GRCm381466,297,025 - 66,311,424 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1466,297,031 - 66,311,424 (+)EnsemblGRCm38mm10GRCm38
MGSCv371466,915,862 - 66,930,261 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361465,251,135 - 65,265,534 (+)NCBIMGSCv36mm8
Celera1464,048,768 - 64,063,173 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.44NCBI
Trim35
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81544,669,222 - 44,685,766 (+)NCBIGRCr8
mRatBN7.21540,493,697 - 40,510,246 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1540,493,755 - 40,510,240 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1542,361,465 - 42,377,916 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01543,511,664 - 43,528,115 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01541,954,041 - 41,970,528 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01542,960,255 - 42,976,798 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1542,960,307 - 42,976,792 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01548,617,499 - 48,633,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41545,730,500 - 45,748,174 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1540,166,644 - 40,183,439 (+)NCBICelera
Cytogenetic Map15p12NCBI
Trim35
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540349,823,222 - 49,841,617 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540349,821,150 - 49,841,634 (-)NCBIChiLan1.0ChiLan1.0
TRIM35
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12530,276,673 - 30,307,059 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2530,276,763 - 30,300,769 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2530,862,769 - 30,893,153 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02530,466,859 - 30,497,202 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2530,466,844 - 30,503,594 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12530,396,764 - 30,427,107 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02530,277,630 - 30,308,059 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02530,444,541 - 30,474,863 (+)NCBIUU_Cfam_GSD_1.0
Trim35
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049438,388,177 - 8,405,075 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936675182,794 - 197,858 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936675181,076 - 197,954 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM35
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1411,027,190 - 11,051,972 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11411,031,667 - 11,051,903 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21412,210,504 - 12,231,955 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM35
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1825,396,829 - 25,423,154 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl825,398,690 - 25,423,079 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605216,721,348 - 16,748,468 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trim35
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475822,034,539 - 22,051,580 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475822,035,096 - 22,051,940 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000054745   ⟹   ENSPPAP00000031880
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl823,757,009 - 23,783,457 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000054752   ⟹   ENSPPAP00000031887
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl823,759,666 - 23,783,379 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000054759   ⟹   ENSPPAP00000031893
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl823,760,228 - 23,783,379 (-)Ensembl
RefSeq Acc Id: XM_003830805   ⟹   XP_003830853
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2745,814,684 - 45,841,408 (-)NCBI
NHGRI_mPanPan1821,528,894 - 21,555,414 (-)NCBI
Mhudiblu_PPA_v0826,554,217 - 26,580,684 (-)NCBI
PanPan1.1823,757,009 - 23,783,457 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003830853 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000031880
  ENSPPAP00000031880.1
  ENSPPAP00000031887.1
  ENSPPAP00000031893.1
Reference Protein Sequences
RefSeq Acc Id: XP_003830853   ⟸   XM_003830805
- UniProtKB: A0A2R9BR31 (UniProtKB/TrEMBL),   A0A2R9BQF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000031880   ⟸   ENSPPAT00000054745
RefSeq Acc Id: ENSPPAP00000031887   ⟸   ENSPPAT00000054752
RefSeq Acc Id: ENSPPAP00000031893   ⟸   ENSPPAT00000054759
Protein Domains
B box-type   B30.2/SPRY   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038841 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054745.1 UniProtKB/TrEMBL
  ENSPPAT00000054752.1 UniProtKB/TrEMBL
  ENSPPAT00000054759.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  Znf-RING_euk UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report pps:100992858 UniProtKB/TrEMBL
NCBI Gene TRIM35 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE TRIM35 UniProtKB/TrEMBL
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-C3HC4_3 UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBOX UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A2R9BQF3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BR31 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BZF5_PANPA UniProtKB/TrEMBL