FHOD3 (formin homology 2 domain containing 3) - Rat Genome Database

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Gene: FHOD3 (formin homology 2 domain containing 3) Pan paniscus
Analyze
Symbol: FHOD3
Name: formin homology 2 domain containing 3
RGD ID: 11885999
Description: ENCODES a protein that exhibits actin filament binding (inferred); INVOLVED IN cardiac myofibril assembly (ortholog); negative regulation of actin filament polymerization (ortholog); sarcomere organization (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); dilated cardiomyopathy (ortholog); genetic disease (ortholog); FOUND IN striated muscle thin filament (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FH1/FH2 domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11839,385,954 - 39,882,417 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01829,550,049 - 30,033,130 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11833,163,910 - 33,590,683 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1833,165,819 - 33,590,154 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FHOD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11839,385,954 - 39,882,417 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01829,550,049 - 30,033,130 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11833,163,910 - 33,590,683 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1833,165,819 - 33,590,154 (+)Ensemblpanpan1.1panPan2
FHOD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381836,297,713 - 36,780,220 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1836,297,713 - 36,780,220 (+)EnsemblGRCh38hg38GRCh38
GRCh371833,877,676 - 34,360,183 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361832,131,700 - 32,614,016 (+)NCBINCBI36Build 36hg18NCBI36
Celera1830,685,614 - 31,169,391 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
HuRef1830,735,778 - 31,218,907 (+)NCBIHuRef
CHM1_11833,804,792 - 34,287,049 (+)NCBICHM1_1
T2T-CHM13v2.01836,489,301 - 36,973,364 (+)NCBIT2T-CHM13v2.0
Fhod3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391824,841,445 - 25,266,564 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1824,841,680 - 25,266,558 (+)EnsemblGRCm39 Ensembl
GRCm381824,708,388 - 25,133,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1824,708,623 - 25,133,501 (+)EnsemblGRCm38mm10GRCm38
MGSCv371824,867,946 - 25,292,002 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361824,852,455 - 25,276,511 (+)NCBIMGSCv36mm8
Celera1825,190,970 - 25,619,254 (+)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1813.18NCBI
Fhod3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81816,267,830 - 16,700,508 (+)NCBIGRCr8
mRatBN7.21815,993,079 - 16,425,796 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1815,993,324 - 16,425,796 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1816,172,154 - 16,612,274 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01816,954,859 - 17,394,934 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01816,242,926 - 16,674,278 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01816,650,786 - 17,332,209 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1816,650,806 - 17,332,210 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01816,410,820 - 16,473,813 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01816,842,427 - 17,086,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41816,487,052 - 16,952,424 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11816,513,673 - 16,615,841 (+)NCBI
Celera1815,913,907 - 16,336,469 (+)NCBICelera
Cytogenetic Map18p12NCBI
Fhod3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540222,821,710 - 23,279,222 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540222,822,060 - 23,277,993 (+)NCBIChiLan1.0ChiLan1.0
FHOD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1753,477,273 - 53,933,532 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl753,478,930 - 53,934,331 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha752,893,761 - 53,356,825 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0753,438,086 - 53,901,223 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl753,438,079 - 53,901,271 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1753,122,091 - 53,584,883 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0753,144,927 - 53,608,076 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0753,437,853 - 53,900,540 (-)NCBIUU_Cfam_GSD_1.0
Fhod3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494449,286,982 - 49,717,492 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365178,614,867 - 9,044,894 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365178,614,384 - 9,044,894 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FHOD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6120,036,845 - 120,586,816 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16120,036,824 - 120,585,987 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26112,902,155 - 113,225,109 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FHOD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11844,053,360 - 44,540,820 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1844,049,837 - 44,540,760 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605018,601,155 - 18,998,789 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fhod3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477910,562,296 - 11,069,694 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477910,562,319 - 11,069,557 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034943477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034943478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034943479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034943480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034943481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034943482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034943483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055102327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055102331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055102332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063597259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000040217   ⟹   ENSPPAP00000017510
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1833,165,819 - 33,590,154 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000040221   ⟹   ENSPPAP00000017514
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1833,165,819 - 33,590,154 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000040225   ⟹   ENSPPAP00000017518
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1833,165,819 - 33,590,154 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000040236   ⟹   ENSPPAP00000017528
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1833,436,755 - 33,590,154 (+)Ensembl
RefSeq Acc Id: XM_034943481   ⟹   XP_034799372
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
NHGRI_mPanPan11839,385,957 - 39,882,417 (+)NCBI
Mhudiblu_PPA_v01829,550,052 - 30,033,130 (+)NCBI
RefSeq Acc Id: XM_034943483   ⟹   XP_034799374
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
NHGRI_mPanPan11839,385,957 - 39,882,417 (+)NCBI
Mhudiblu_PPA_v01829,550,052 - 30,033,130 (+)NCBI
RefSeq Acc Id: XM_055102327   ⟹   XP_054958302
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
NHGRI_mPanPan11839,385,954 - 39,882,417 (+)NCBI
RefSeq Acc Id: XM_055102331   ⟹   XP_054958306
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
NHGRI_mPanPan11839,385,957 - 39,882,417 (+)NCBI
RefSeq Acc Id: XM_055102332   ⟹   XP_054958307
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
NHGRI_mPanPan11839,385,956 - 39,882,417 (+)NCBI
RefSeq Acc Id: XM_063597250   ⟹   XP_063453320
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
RefSeq Acc Id: XM_063597251   ⟹   XP_063453321
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
RefSeq Acc Id: XM_063597252   ⟹   XP_063453322
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
RefSeq Acc Id: XM_063597253   ⟹   XP_063453323
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
RefSeq Acc Id: XM_063597254   ⟹   XP_063453324
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
RefSeq Acc Id: XM_063597255   ⟹   XP_063453325
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
RefSeq Acc Id: XM_063597256   ⟹   XP_063453326
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
RefSeq Acc Id: XM_063597257   ⟹   XP_063453327
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
RefSeq Acc Id: XM_063597258   ⟹   XP_063453328
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBI
RefSeq Acc Id: XM_063597259   ⟹   XP_063453329
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21753,750,919 - 54,176,038 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034799372   ⟸   XM_034943481
- Peptide Label: isoform X9
- UniProtKB: A0A2R9ARM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034799374   ⟸   XM_034943483
- Peptide Label: isoform X13
- UniProtKB: A0A2R9ARM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000017510   ⟸   ENSPPAT00000040217
RefSeq Acc Id: ENSPPAP00000017514   ⟸   ENSPPAT00000040221
RefSeq Acc Id: ENSPPAP00000017518   ⟸   ENSPPAT00000040225
RefSeq Acc Id: ENSPPAP00000017528   ⟸   ENSPPAT00000040236
RefSeq Acc Id: XP_054958302   ⟸   XM_055102327
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054958307   ⟸   XM_055102332
- Peptide Label: isoform X12
RefSeq Acc Id: XP_054958306   ⟸   XM_055102331
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063453320   ⟸   XM_063597250
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063453323   ⟸   XM_063597253
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063453322   ⟸   XM_063597252
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063453324   ⟸   XM_063597254
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063453326   ⟸   XM_063597256
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063453321   ⟸   XM_063597251
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063453325   ⟸   XM_063597255
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063453328   ⟸   XM_063597258
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063453327   ⟸   XM_063597257
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063453329   ⟸   XM_063597259
- Peptide Label: isoform X15
Protein Domains
DAD   FH2   GBD/FH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031797 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040217.1 UniProtKB/TrEMBL
  ENSPPAT00000040221.1 UniProtKB/TrEMBL
  ENSPPAT00000040225.1 UniProtKB/TrEMBL
  ENSPPAT00000040236.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.2220 UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DAD_dom UniProtKB/TrEMBL
  FH2_Formin UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/TrEMBL
  FHOD1_GBD_N UniProtKB/TrEMBL
  GBD/FH3_dom UniProtKB/TrEMBL
NCBI Gene FHOD3 ENTREZGENE
PANTHER FH1/FH2 DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
  FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I UniProtKB/TrEMBL
Pfam FH2 UniProtKB/TrEMBL
  Formin_GBD_N UniProtKB/TrEMBL
PROSITE DAD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
  GBD_FH3 UniProtKB/TrEMBL
SMART FH2 UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A2R9AKA3_PANPA UniProtKB/TrEMBL
  A0A2R9AKB3_PANPA UniProtKB/TrEMBL
  A0A2R9AP65_PANPA UniProtKB/TrEMBL
  A0A2R9ARM0 ENTREZGENE, UniProtKB/TrEMBL