GHRH (growth hormone releasing hormone) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: GHRH (growth hormone releasing hormone) Pan paniscus
Analyze
Symbol: GHRH
Name: growth hormone releasing hormone
RGD ID: 11882888
Description: ENCODES a protein that exhibits growth hormone-releasing hormone activity (ortholog); INVOLVED IN adenohypophysis development (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 5 (ortholog); Alzheimer's disease (ortholog); autoimmune polyendocrine syndrome type 1 (ortholog); FOUND IN axon terminus (ortholog); extracellular space (ortholog); perikaryon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: somatoliberin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22142,978,526 - 42,985,770 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12042,971,567 - 42,978,804 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02033,573,001 - 33,583,699 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12034,687,587 - 34,693,258 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2034,687,587 - 34,693,240 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GHRH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22142,978,526 - 42,985,770 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12042,971,567 - 42,978,804 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02033,573,001 - 33,583,699 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12034,687,587 - 34,693,258 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2034,687,587 - 34,693,240 (-)Ensemblpanpan1.1panPan2
GHRH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382037,251,086 - 37,261,814 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2037,251,086 - 37,261,819 (-)EnsemblGRCh38hg38GRCh38
GRCh372035,879,489 - 35,890,217 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362035,312,903 - 35,318,706 (-)NCBINCBI36Build 36hg18NCBI36
Build 342035,312,902 - 35,318,706NCBI
Celera2032,586,769 - 32,592,579 (-)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2032,615,081 - 32,620,891 (-)NCBIHuRef
CHM1_12035,782,445 - 35,788,255 (-)NCBICHM1_1
T2T-CHM13v2.02038,975,156 - 38,985,884 (-)NCBIT2T-CHM13v2.0
Ghrh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392157,171,416 - 157,190,645 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2157,171,417 - 157,189,426 (-)EnsemblGRCm39 Ensembl
GRCm382157,329,496 - 157,348,725 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2157,329,497 - 157,347,506 (-)EnsemblGRCm38mm10GRCm38
MGSCv372157,155,232 - 157,172,391 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362157,020,942 - 157,038,038 (-)NCBIMGSCv36mm8
Celera2163,265,842 - 163,283,112 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.25NCBI
Ghrh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83166,412,763 - 166,432,519 (-)NCBIGRCr8
mRatBN7.23145,992,762 - 146,012,528 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3145,992,763 - 146,011,889 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3149,818,121 - 149,837,238 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03158,319,491 - 158,338,548 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03156,060,811 - 156,079,879 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03153,449,124 - 153,468,794 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3153,449,125 - 153,468,794 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03158,251,824 - 158,270,812 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43148,027,235 - 148,046,352 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13147,933,144 - 147,952,261 (-)NCBI
Celera3144,698,178 - 144,717,216 (-)NCBICelera
Cytogenetic Map3q42NCBI
Ghrh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542224,481,246 - 24,490,529 (+)NCBIChiLan1.0ChiLan1.0
GHRH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12425,893,224 - 25,902,095 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2425,893,225 - 25,897,712 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2425,542,127 - 25,546,302 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02426,590,708 - 26,594,898 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2426,590,708 - 26,594,883 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12425,867,994 - 25,872,168 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02425,973,219 - 25,977,394 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02426,462,493 - 26,466,667 (-)NCBIUU_Cfam_GSD_1.0
Ghrh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640174,794,985 - 174,803,395 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365613,950,340 - 3,952,405 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365613,946,256 - 3,954,472 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GHRH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1740,387,344 - 40,397,857 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11740,386,725 - 40,398,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21745,876,581 - 45,887,302 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GHRH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1226,482,734 - 26,493,761 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl226,487,973 - 26,493,499 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605075,362,464 - 75,373,119 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ghrh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046251466,381 - 13,318 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046251465,484 - 8,763 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000047251   ⟹   ENSPPAP00000024426
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2034,687,587 - 34,693,240 (-)Ensembl
RefSeq Acc Id: XM_008957288   ⟹   XP_008955536
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22142,978,526 - 42,985,770 (-)NCBI
NHGRI_mPanPan12042,971,567 - 42,978,804 (-)NCBI
Mhudiblu_PPA_v02033,573,001 - 33,579,054 (-)NCBI
PanPan1.12034,687,587 - 34,693,258 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063600861   ⟹   XP_063456931
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22142,980,364 - 42,985,770 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008955536 (Get FASTA)   NCBI Sequence Viewer  
  XP_063456931 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024426
  ENSPPAP00000024426.1
Reference Protein Sequences
RefSeq Acc Id: XP_008955536   ⟸   XM_008957288
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B5V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000024426   ⟸   ENSPPAT00000047251
RefSeq Acc Id: XP_063456931   ⟸   XM_063600861
- Peptide Label: isoform X1
Protein Domains
Glucagon / GIP / secretin / VIP family


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035360 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047251.1 UniProtKB/TrEMBL
InterPro Glucagon_GIP_secretin_VIP UniProtKB/TrEMBL
  VIP/GHRH-like UniProtKB/TrEMBL
KEGG Report pps:100974217 UniProtKB/TrEMBL
NCBI Gene GHRH ENTREZGENE
PANTHER PTHR11213 UniProtKB/TrEMBL
  SOMATOLIBERIN UniProtKB/TrEMBL
Pfam Hormone_2 UniProtKB/TrEMBL
PROSITE GLUCAGON UniProtKB/TrEMBL
SMART GLUCA UniProtKB/TrEMBL
UniProt A0A2R9B5V6 ENTREZGENE, UniProtKB/TrEMBL