EPN3 (epsin 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: EPN3 (epsin 3) Pan paniscus
Analyze
Symbol: EPN3
Name: epsin 3
RGD ID: 11878325
Description: ENCODES a protein that exhibits clathrin binding (inferred); EH domain binding (inferred); lipid binding (inferred); INVOLVED IN endocytosis (inferred); ASSOCIATED WITH diastolic heart failure (ortholog); genetic disease (ortholog); trichodontoosseous syndrome (ortholog); FOUND IN clathrin vesicle coat (inferred); clathrin-coated pit (inferred); clathrin-coated vesicle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: epsin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21966,723,444 - 66,733,341 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11771,530,674 - 71,540,606 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01744,626,114 - 44,636,646 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11749,500,146 - 49,511,242 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1749,504,119 - 49,509,729 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
endocytosis  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EPN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21966,723,444 - 66,733,341 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11771,530,674 - 71,540,606 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01744,626,114 - 44,636,646 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11749,500,146 - 49,511,242 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1749,504,119 - 49,509,729 (+)Ensemblpanpan1.1panPan2
EPN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381750,532,735 - 50,543,750 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1750,532,682 - 50,543,750 (+)EnsemblGRCh38hg38GRCh38
GRCh371748,610,096 - 48,621,111 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361745,965,047 - 45,976,110 (+)NCBINCBI36Build 36hg18NCBI36
Build 341745,965,097 - 45,975,160NCBI
Celera1745,071,411 - 45,082,475 (+)NCBICelera
Cytogenetic Map17q21.33NCBI
HuRef1743,978,042 - 43,989,066 (+)NCBIHuRef
CHM1_11748,673,927 - 48,684,990 (+)NCBICHM1_1
T2T-CHM13v2.01751,399,907 - 51,410,883 (+)NCBIT2T-CHM13v2.0
Epn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,380,425 - 94,390,800 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1194,380,425 - 94,390,800 (-)EnsemblGRCm39 Ensembl
GRCm381194,489,599 - 94,499,974 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1194,489,599 - 94,499,974 (-)EnsemblGRCm38mm10GRCm38
MGSCv371194,350,913 - 94,361,288 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361194,307,081 - 94,316,013 (-)NCBIMGSCv36mm8
Celera11104,109,936 - 104,120,324 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1158.9NCBI
Epn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81079,935,857 - 79,946,121 (-)NCBIGRCr8
mRatBN7.21079,438,978 - 79,449,516 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1079,438,978 - 79,447,356 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1084,043,695 - 84,052,073 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01083,541,809 - 83,550,187 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01079,056,554 - 79,064,944 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01082,220,762 - 82,231,200 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,220,762 - 82,229,140 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01082,040,627 - 82,050,793 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,129,023 - 83,137,401 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11083,143,392 - 83,151,771 (-)NCBI
Celera1078,228,056 - 78,236,434 (-)NCBICelera
Cytogenetic Map10q26NCBI
Epn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545111,209,634 - 11,215,073 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545111,209,454 - 11,218,427 (-)NCBIChiLan1.0ChiLan1.0
EPN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1926,454,340 - 26,465,236 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl926,457,776 - 26,463,637 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha925,847,087 - 25,856,322 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0927,248,587 - 27,257,821 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl927,251,961 - 27,261,658 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1926,016,329 - 26,025,564 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0926,274,894 - 26,284,151 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0926,405,091 - 26,414,325 (+)NCBIUU_Cfam_GSD_1.0
Epn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560225,890,919 - 25,900,062 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649011,174,276 - 11,184,517 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649011,174,552 - 11,184,516 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1226,815,461 - 26,825,482 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11226,812,653 - 26,825,485 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21226,890,808 - 26,903,644 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EPN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11642,795,578 - 42,804,907 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1642,795,782 - 42,805,136 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607713,510,624 - 13,521,822 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Epn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247956,418,770 - 6,428,013 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247956,418,568 - 6,427,624 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000060061   ⟹   ENSPPAP00000037163
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1749,504,119 - 49,509,729 (+)Ensembl
RefSeq Acc Id: XM_003817443   ⟹   XP_003817491
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21966,723,444 - 66,733,341 (+)NCBI
NHGRI_mPanPan11771,530,674 - 71,540,606 (+)NCBI
Mhudiblu_PPA_v01744,626,114 - 44,636,646 (+)NCBI
PanPan1.11749,500,146 - 49,511,242 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034942446   ⟹   XP_034798337
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21966,723,448 - 66,733,341 (+)NCBI
NHGRI_mPanPan11771,530,675 - 71,540,606 (+)NCBI
Mhudiblu_PPA_v01744,626,116 - 44,636,646 (+)NCBI
RefSeq Acc Id: XM_034942447   ⟹   XP_034798338
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21966,723,448 - 66,733,341 (+)NCBI
NHGRI_mPanPan11771,530,675 - 71,540,606 (+)NCBI
Mhudiblu_PPA_v01744,626,116 - 44,636,646 (+)NCBI
RefSeq Acc Id: XM_034942448   ⟹   XP_034798339
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21966,725,274 - 66,733,341 (+)NCBI
NHGRI_mPanPan11771,532,580 - 71,540,606 (+)NCBI
Mhudiblu_PPA_v01744,628,009 - 44,636,646 (+)NCBI
RefSeq Acc Id: XM_034942449   ⟹   XP_034798340
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21966,723,448 - 66,733,341 (+)NCBI
NHGRI_mPanPan11771,530,675 - 71,540,606 (+)NCBI
Mhudiblu_PPA_v01744,626,115 - 44,636,646 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003817491 (Get FASTA)   NCBI Sequence Viewer  
  XP_034798337 (Get FASTA)   NCBI Sequence Viewer  
  XP_034798338 (Get FASTA)   NCBI Sequence Viewer  
  XP_034798339 (Get FASTA)   NCBI Sequence Viewer  
  XP_034798340 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000037163.1
Reference Protein Sequences
RefSeq Acc Id: XP_003817491   ⟸   XM_003817443
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_034798340   ⟸   XM_034942449
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034798337   ⟸   XM_034942446
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034798338   ⟸   XM_034942447
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034798339   ⟸   XM_034942448
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000037163   ⟸   ENSPPAT00000060061
Protein Domains
ENTH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041326 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060061.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.90 UniProtKB/TrEMBL
InterPro ENTH UniProtKB/TrEMBL
  ENTH_VHS UniProtKB/TrEMBL
  UIM_dom UniProtKB/TrEMBL
NCBI Gene EPN3 ENTREZGENE
PANTHER EPSIN/ENT-RELATED UniProtKB/TrEMBL
  PTHR12276:SF16 UniProtKB/TrEMBL
Pfam ENTH UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
PROSITE ENTH UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
SMART ENTH UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
Superfamily-SCOP SSF48464 UniProtKB/TrEMBL
UniProt A0A2R9C895_PANPA UniProtKB/TrEMBL