CYP2C19 (cytochrome P450 family 2 subfamily C member 19) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: CYP2C19 (cytochrome P450 family 2 subfamily C member 19) Pan paniscus
Analyze
Symbol: CYP2C19
Name: cytochrome P450 family 2 subfamily C member 19
RGD ID: 11877766
Description: ENCODES a protein that exhibits arachidonic acid 11,12-epoxygenase activity (ortholog); arachidonic acid 14,15-epoxygenase activity (ortholog); enzyme binding (ortholog); INVOLVED IN arachidonic acid metabolic process (ortholog); drug metabolic process (ortholog); exogenous drug catabolic process (ortholog); PARTICIPATES IN axitinib pharmacokinetics pathway; carbamazepine pharmacokinetics pathway; citalopram pharmacodynamics pathway; ASSOCIATED WITH acute kidney failure (ortholog); Allergic Rhinoconjunctivitis (ortholog); atrial fibrillation (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: cytochrome P450 2C19; LOC100995695
RGD Orthologs
Human
Mouse
Rat
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11094,883,037 - 94,972,353 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1094,884,472 - 94,970,065 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01091,375,255 - 91,465,215 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
CYP2C19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11094,883,037 - 94,972,353 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1094,884,472 - 94,970,065 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01091,375,255 - 91,465,215 (+)NCBIMhudiblu_PPA_v0panPan3
CYP2C19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1094,762,681 - 94,855,547 (+)EnsemblGRCh38hg38GRCh38
GRCh381094,762,681 - 94,855,547 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371096,522,438 - 96,615,304 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361096,512,453 - 96,602,661 (+)NCBINCBI36hg18NCBI36
Build 341096,512,452 - 96,602,661NCBI
Celera1090,262,555 - 90,352,777 (+)NCBI
Cytogenetic Map10q23.33NCBI
HuRef1090,149,122 - 90,239,340 (+)NCBIHuRef
CHM1_11096,804,187 - 96,894,726 (+)NCBICHM1_1
Cyp2c38
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391939,378,000 - 39,451,547 (-)NCBIGRCm39mm39
GRCm39 Ensembl1939,378,000 - 39,451,519 (-)Ensembl
GRCm381939,389,556 - 39,463,103 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1939,389,556 - 39,463,075 (-)EnsemblGRCm38mm10GRCm38
MGSCv371939,464,046 - 39,537,565 (-)NCBIGRCm37mm9NCBIm37
MGSCv361939,442,867 - 39,516,386 (-)NCBImm8
MGSCv361939,107,245 - 39,170,091 (-)NCBImm8
Celera1940,194,429 - 40,266,552 (-)NCBICelera
Cytogenetic Map19C3NCBI
Cyp2c6v1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21237,938,521 - 237,976,238 (+)NCBI
Rnor_6.0 Ensembl1147,713,892 - 147,888,007 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01147,713,879 - 147,814,410 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01153,451,394 - 153,454,476 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01154,005,928 - 154,103,310 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,859,015 - 243,896,003 (+)ENTREZGENERGSC3.4rn4RGSC3.4
Celera1137,119,477 - 137,156,491 (+)NCBICelera
Cytogenetic Map1q31NCBI
CYP2C49
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.114106,571,803 - 106,612,082 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214116,191,543 - 116,244,868 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYP2C19
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1987,981,300 - 88,025,007 (+)NCBI
Vero_WHO_p1.0NW_02366604848,761,705 - 48,797,570 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000046156   ⟹   ENSPPAP00000023332
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1094,884,472 - 94,970,065 (+)Ensembl
RefSeq Acc Id: XM_003825386   ⟹   XP_003825434
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11094,884,648 - 94,972,353 (+)NCBI
Mhudiblu_PPA_v01091,376,819 - 91,465,215 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008950697   ⟹   XP_008948945
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11094,883,037 - 94,969,996 (+)NCBI
Mhudiblu_PPA_v01091,375,255 - 91,463,231 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003825434 (Get FASTA)   NCBI Sequence Viewer  
  XP_008948945 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008948945   ⟸   XM_008950697
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003825434   ⟸   XM_003825386
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSPPAP00000023332   ⟸   ENSPPAT00000046156


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034854 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000023332 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046156 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/TrEMBL
KEGG Report pps:100995695 UniProtKB/TrEMBL
NCBI Gene LOC100995695 ENTREZGENE
Pfam p450 UniProtKB/TrEMBL
PRINTS EP450I UniProtKB/TrEMBL
  P450 UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/TrEMBL
UniProt A0A2R9B7Q9_PANPA UniProtKB/TrEMBL
VGNC ID VGNC:83028 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-25 CYP2C19  cytochrome P450 family 2 subfamily C member 19  LOC100995695  cytochrome P450 2C19  Symbol and/or name change 5135510 APPROVED