PRPF19 (pre-mRNA processing factor 19) - Rat Genome Database

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Gene: PRPF19 (pre-mRNA processing factor 19) Pan paniscus
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Symbol: PRPF19
Name: pre-mRNA processing factor 19
RGD ID: 11877575
Description: ENCODES a protein that exhibits identical protein binding (inferred); transferase activity (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN lipid biosynthetic process (ortholog); positive regulation of astrocyte differentiation (ortholog); positive regulation of mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Disease Progression (ortholog); genetic disease (ortholog); Hydrops Fetalis (ortholog); FOUND IN DNA replication factor A complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pre-mRNA-processing factor 19; PRP19/PSO4 pre-mRNA processing factor 19 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2962,060,030 - 62,075,933 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,103,880 - 63,119,960 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,153,965 - 56,169,821 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,594,508 - 59,610,544 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,595,120 - 59,607,828 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PRPF19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2962,060,030 - 62,075,933 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,103,880 - 63,119,960 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,153,965 - 56,169,821 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,594,508 - 59,610,544 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,595,120 - 59,607,828 (-)Ensemblpanpan1.1panPan2
PRPF19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,890,547 - 60,906,585 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1160,890,547 - 60,906,585 (-)EnsemblGRCh38hg38GRCh38
GRCh371160,658,019 - 60,674,057 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,414,778 - 60,430,632 (-)NCBINCBI36Build 36hg18NCBI36
Build 341160,414,779 - 60,430,632NCBI
Celera1158,018,905 - 58,034,947 (-)NCBICelera
Cytogenetic Map11q12.2NCBI
HuRef1157,004,177 - 57,020,231 (-)NCBIHuRef
CHM1_11160,524,333 - 60,540,362 (-)NCBICHM1_1
T2T-CHM13v2.01160,841,704 - 60,857,730 (-)NCBIT2T-CHM13v2.0
Prpf19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,872,595 - 10,886,923 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,872,595 - 10,886,923 (+)EnsemblGRCm39 Ensembl
GRCm381910,895,231 - 10,909,559 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,895,231 - 10,909,559 (+)EnsemblGRCm38mm10GRCm38
MGSCv371910,969,782 - 10,980,022 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361910,962,337 - 10,972,577 (+)NCBIMGSCv36mm8
Celera1911,588,283 - 11,598,524 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map197.33NCBI
Prpf19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,966,104 - 216,977,549 (+)NCBIGRCr8
mRatBN7.21207,541,582 - 207,552,664 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1207,541,595 - 207,552,662 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,916,453 - 215,927,495 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,977,172 - 222,988,219 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01215,670,849 - 215,681,892 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01226,947,065 - 226,958,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,947,105 - 226,958,144 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01234,012,625 - 234,023,696 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41213,390,564 - 213,401,943 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11213,548,971 - 213,560,061 (+)NCBI
Celera1205,034,192 - 205,044,837 (+)NCBICelera
Cytogenetic Map1q43NCBI
Prpf19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555115,545,989 - 5,557,792 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555115,546,212 - 5,552,368 (-)NCBIChiLan1.0ChiLan1.0
PRPF19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11855,389,902 - 55,400,241 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1855,389,897 - 55,400,240 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1853,963,071 - 53,973,417 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01856,438,338 - 56,448,620 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1856,438,256 - 56,448,616 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11855,495,828 - 55,506,178 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01855,117,335 - 55,127,674 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01855,998,460 - 56,008,827 (+)NCBIUU_Cfam_GSD_1.0
Prpf19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494711,918,067 - 11,928,483 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365812,031,822 - 2,042,424 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365812,031,894 - 2,042,294 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRPF19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl210,851,579 - 10,860,836 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1210,851,779 - 10,860,315 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2210,457,428 - 10,465,965 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRPF19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,942,238 - 12,958,853 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,942,213 - 12,959,947 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038110,310,291 - 110,326,283 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prpf19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624926266,159 - 274,529 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624926268,965 - 274,634 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000036951   ⟹   ENSPPAP00000014271
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1159,595,120 - 59,607,828 (-)Ensembl
RefSeq Acc Id: XM_003826325   ⟹   XP_003826373
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2962,060,030 - 62,075,933 (-)NCBI
NHGRI_mPanPan11163,103,880 - 63,119,960 (-)NCBI
Mhudiblu_PPA_v01156,153,965 - 56,169,821 (-)NCBI
PanPan1.11159,594,508 - 59,610,544 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034932706   ⟹   XP_034788597
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2962,060,030 - 62,075,878 (-)NCBI
NHGRI_mPanPan11163,103,880 - 63,119,909 (-)NCBI
Mhudiblu_PPA_v01156,154,338 - 56,169,812 (-)NCBI
RefSeq Acc Id: XM_034932707   ⟹   XP_034788598
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2962,060,030 - 62,074,609 (-)NCBI
NHGRI_mPanPan11163,103,880 - 63,118,638 (-)NCBI
Mhudiblu_PPA_v01156,154,338 - 56,168,544 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003826373 (Get FASTA)   NCBI Sequence Viewer  
  XP_034788597 (Get FASTA)   NCBI Sequence Viewer  
  XP_034788598 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000014271
  ENSPPAP00000014271.1
RefSeq Acc Id: XP_003826373   ⟸   XM_003826325
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ABK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034788597   ⟸   XM_034932706
- Peptide Label: isoform X2
- UniProtKB: A0A2R9ABK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034788598   ⟸   XM_034932707
- Peptide Label: isoform X2
- UniProtKB: A0A2R9ABK4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000014271   ⟸   ENSPPAT00000036951
Protein Domains
U-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030246 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036951.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  Pre-mRNA_splic_Prp19 UniProtKB/TrEMBL
  Prp19 UniProtKB/TrEMBL
  Ubox_domain UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene PRPF19 ENTREZGENE
PANTHER PRE-MRNA-PROCESSING FACTOR 19 UniProtKB/TrEMBL
  PTHR43995 UniProtKB/TrEMBL
Pfam Prp19 UniProtKB/TrEMBL
  U-box UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE RICIN_B_LECTIN UniProtKB/TrEMBL
  U_BOX UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART Ubox UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
UniProt A0A2R9ABK4 ENTREZGENE, UniProtKB/TrEMBL