EXD3 (exonuclease 3'-5' domain containing 3) - Rat Genome Database

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Gene: EXD3 (exonuclease 3'-5' domain containing 3) Pan paniscus
Analyze
Symbol: EXD3
Name: exonuclease 3'-5' domain containing 3
RGD ID: 11876801
Description: ENCODES a protein that exhibits 3'-5' exonuclease activity (inferred); exonuclease activity (inferred); hydrolase activity (inferred); INVOLVED IN nucleobase-containing compound metabolic process (inferred); ASSOCIATED WITH Adams-Oliver Syndrome 5 (ortholog); autosomal dominant intellectual developmental disorder 8 (ortholog); developmental and epileptic encephalopathy 14 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: exonuclease mut-7 homolog; probable exonuclease mut-7 homolog
RGD Orthologs
Human
Chinchilla
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2111,968,782 - 2,093,191 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan191,971,121 - 2,095,523 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,366,206 - 108,490,346 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,336,229 - 137,427,312 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,336,229 - 137,427,312 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
EXD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2111,968,782 - 2,093,191 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan191,971,121 - 2,095,523 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,366,206 - 108,490,346 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,336,229 - 137,427,312 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,336,229 - 137,427,312 (-)Ensemblpanpan1.1panPan2
EXD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,306,896 - 137,423,162 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,306,896 - 137,423,211 (-)EnsemblGRCh38hg38GRCh38
GRCh379140,201,348 - 140,317,614 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,321,169 - 139,437,535 (-)NCBINCBI36Build 36hg18NCBI36
Celera9110,717,558 - 110,832,531 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,660,651 - 109,754,280 (-)NCBIHuRef
CHM1_19140,350,082 - 140,466,446 (-)NCBICHM1_1
T2T-CHM13v2.09149,544,816 - 149,673,783 (-)NCBIT2T-CHM13v2.0
Exd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555135,314,370 - 5,336,052 (-)NCBIChiLan1.0ChiLan1.0
EXD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,311,700 - 48,393,469 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,344,938 - 48,390,113 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,498,632 - 47,580,199 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,173,556 - 49,255,066 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,206,792 - 49,251,710 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,949,925 - 48,031,491 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,248,886 - 48,330,201 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,295,398 - 48,377,135 (+)NCBIUU_Cfam_GSD_1.0
EXD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21314,022,471 - 314,078,845 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EXD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112768,218 - 884,103 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12803,896 - 884,049 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660584,424,921 - 4,577,617 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034929641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055117412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063594075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063594077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063594078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063594079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063594080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063594081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063594082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063594083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000062383   ⟹   ENSPPAP00000039472
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9137,336,229 - 137,427,312 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000062390   ⟹   ENSPPAP00000039479
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9137,397,072 - 137,427,312 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000062398   ⟹   ENSPPAP00000039487
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9137,425,279 - 137,427,259 (-)Ensembl
RefSeq Acc Id: XM_034929641   ⟹   XP_034785532
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,782 - 2,093,191 (+)NCBI
NHGRI_mPanPan191,971,124 - 2,095,523 (+)NCBI
Mhudiblu_PPA_v09108,366,206 - 108,490,346 (-)NCBI
RefSeq Acc Id: XM_055117402   ⟹   XP_054973377
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,787 - 2,093,191 (+)NCBI
NHGRI_mPanPan191,971,124 - 2,095,523 (+)NCBI
RefSeq Acc Id: XM_055117403   ⟹   XP_054973378
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,971,071 - 2,093,191 (+)NCBI
NHGRI_mPanPan191,977,085 - 2,095,523 (+)NCBI
RefSeq Acc Id: XM_055117404   ⟹   XP_054973379
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,991,666 - 2,093,191 (+)NCBI
NHGRI_mPanPan191,993,984 - 2,095,523 (+)NCBI
RefSeq Acc Id: XM_055117405   ⟹   XP_054973380
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,785 - 2,083,988 (+)NCBI
NHGRI_mPanPan191,971,122 - 2,086,302 (+)NCBI
RefSeq Acc Id: XM_055117406   ⟹   XP_054973381
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,785 - 2,083,988 (+)NCBI
NHGRI_mPanPan191,971,122 - 2,086,302 (+)NCBI
RefSeq Acc Id: XM_055117407   ⟹   XP_054973382
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,900 - 2,093,191 (+)NCBI
NHGRI_mPanPan191,971,233 - 2,095,523 (+)NCBI
RefSeq Acc Id: XM_055117408   ⟹   XP_054973383
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,786 - 2,093,191 (+)NCBI
NHGRI_mPanPan191,971,125 - 2,095,523 (+)NCBI
RefSeq Acc Id: XM_055117409   ⟹   XP_054973384
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,785 - 2,090,479 (+)NCBI
NHGRI_mPanPan191,971,124 - 2,092,817 (+)NCBI
RefSeq Acc Id: XM_055117411   ⟹   XP_054973386
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,784 - 2,026,736 (+)NCBI
NHGRI_mPanPan191,971,121 - 2,029,068 (+)NCBI
RefSeq Acc Id: XM_055117412   ⟹   XP_054973387
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,974,997 - 2,026,736 (+)NCBI
NHGRI_mPanPan191,977,430 - 2,029,067 (+)NCBI
RefSeq Acc Id: XM_063594075   ⟹   XP_063450145
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,982,749 - 2,093,191 (+)NCBI
RefSeq Acc Id: XM_063594077   ⟹   XP_063450147
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,975,013 - 2,093,191 (+)NCBI
RefSeq Acc Id: XM_063594078   ⟹   XP_063450148
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,787 - 2,093,191 (+)NCBI
RefSeq Acc Id: XM_063594079   ⟹   XP_063450149
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,970,868 - 2,092,479 (+)NCBI
RefSeq Acc Id: XM_063594080   ⟹   XP_063450150
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,785 - 2,089,709 (+)NCBI
RefSeq Acc Id: XM_063594081   ⟹   XP_063450151
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,786 - 2,089,709 (+)NCBI
RefSeq Acc Id: XM_063594082   ⟹   XP_063450152
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,968,785 - 2,090,550 (+)NCBI
RefSeq Acc Id: XM_063594083   ⟹   XP_063450153
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2111,997,019 - 2,093,191 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034785532   ⟸   XM_034929641
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CMV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000039479   ⟸   ENSPPAT00000062390
RefSeq Acc Id: ENSPPAP00000039487   ⟸   ENSPPAT00000062398
RefSeq Acc Id: ENSPPAP00000039472   ⟸   ENSPPAT00000062383
RefSeq Acc Id: XP_054973386   ⟸   XM_055117411
- Peptide Label: isoform X13
- UniProtKB: A0A2R9CC76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054973380   ⟸   XM_055117405
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CMV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054973381   ⟸   XM_055117406
- Peptide Label: isoform X4
- UniProtKB: A0A2R9CMV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054973377   ⟸   XM_055117402
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CMV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054973384   ⟸   XM_055117409
- Peptide Label: isoform X9
- UniProtKB: A0A2R9CMV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054973383   ⟸   XM_055117408
- Peptide Label: isoform X6
- UniProtKB: A0A2R9CMV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054973382   ⟸   XM_055117407
- Peptide Label: isoform X5
- UniProtKB: A0A2R9CMV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054973378   ⟸   XM_055117403
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CMV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054973387   ⟸   XM_055117412
- Peptide Label: isoform X13
- UniProtKB: A0A2R9CC76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054973379   ⟸   XM_055117404
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CMV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063450152   ⟸   XM_063594082
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063450150   ⟸   XM_063594080
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063450151   ⟸   XM_063594081
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063450148   ⟸   XM_063594078
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063450149   ⟸   XM_063594079
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063450147   ⟸   XM_063594077
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063450145   ⟸   XM_063594075
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063450153   ⟸   XM_063594083
- Peptide Label: isoform X12
Protein Domains
3'-5' exonuclease


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042435 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062383.1 UniProtKB/TrEMBL
  ENSPPAT00000062390.1 UniProtKB/TrEMBL
  ENSPPAT00000062398.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.10 UniProtKB/TrEMBL
InterPro 3'-5'_exonuclease_dom UniProtKB/TrEMBL
  Mut-7_DEDDy_dom UniProtKB/TrEMBL
  Mut7-C_RNAse_dom UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
NCBI Gene EXD3 ENTREZGENE
PANTHER 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  EXONUCLEASE MUT-7 HOMOLOG UniProtKB/TrEMBL
Pfam DNA_pol_A_exo1 UniProtKB/TrEMBL
  Mut7-C UniProtKB/TrEMBL
SMART 35EXOc UniProtKB/TrEMBL
Superfamily-SCOP SSF53098 UniProtKB/TrEMBL
UniProt A0A2R9CC76 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CMV2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CMW2_PANPA UniProtKB/TrEMBL