UCN3 (urocortin 3) - Rat Genome Database

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Gene: UCN3 (urocortin 3) Pan paniscus
Analyze
Symbol: UCN3
Name: urocortin 3
RGD ID: 11873340
Description: ENCODES a protein that exhibits corticotropin-releasing hormone receptor 2 binding (inferred); corticotropin-releasing hormone receptor binding (inferred); hormone activity (inferred); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cellular response to hypoxia (ortholog); cellular response to nutrient levels (ortholog); PARTICIPATES IN corticotropin-releasing hormone signaling pathway; ASSOCIATED WITH genetic disease (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); Inflammation (ortholog); FOUND IN axon (ortholog); axon terminus (ortholog); varicosity (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: urocortin 3 (stresscopin); urocortin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2817,930,638 - 17,931,123 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11017,935,959 - 17,936,444 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0105,410,501 - 5,419,650 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1105,398,032 - 5,406,168 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl105,405,683 - 5,406,168 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UCN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2817,930,638 - 17,931,123 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11017,935,959 - 17,936,444 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0105,410,501 - 5,419,650 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1105,398,032 - 5,406,168 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl105,405,683 - 5,406,168 (+)Ensemblpanpan1.1panPan2
UCN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38105,364,966 - 5,374,692 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl105,364,966 - 5,374,692 (+)EnsemblGRCh38hg38GRCh38
GRCh37105,406,929 - 5,416,655 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36105,396,976 - 5,406,169 (+)NCBINCBI36Build 36hg18NCBI36
Build 34105,396,975 - 5,406,169NCBI
Celera105,339,562 - 5,339,918 (+)NCBICelera
Cytogenetic Map10p15.1NCBI
HuRef105,338,811 - 5,339,167 (+)NCBIHuRef
CHM1_1105,406,973 - 5,416,168 (+)NCBICHM1_1
T2T-CHM13v2.0105,366,734 - 5,377,963 (+)NCBIT2T-CHM13v2.0
Ucn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,990,688 - 3,995,349 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,990,688 - 3,995,349 (-)EnsemblGRCm39 Ensembl
GRCm38133,940,688 - 3,945,349 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,940,688 - 3,945,349 (-)EnsemblGRCm38mm10GRCm38
MGSCv37133,939,934 - 3,944,595 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,940,402 - 3,940,896 (-)NCBIMGSCv36mm8
Celera133,927,567 - 3,932,226 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map132.2NCBI
Ucn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81771,219,611 - 71,225,904 (+)NCBIGRCr8
mRatBN7.21766,309,748 - 66,315,996 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1766,309,371 - 66,315,990 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1769,783,706 - 69,790,010 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01773,612,535 - 73,618,839 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01767,655,540 - 67,661,838 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01769,959,879 - 69,966,532 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1769,960,160 - 69,966,099 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01771,663,483 - 71,670,090 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,482,852 - 77,488,471 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1765,815,485 - 65,821,104 (+)NCBICelera
Cytogenetic Map17q12.2NCBI
Ucn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955463218,456 - 218,959 (+)NCBIChiLan1.0ChiLan1.0
UCN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1230,541,316 - 30,547,839 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl230,541,779 - 30,542,282 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha227,570,906 - 27,577,392 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0230,921,836 - 30,928,322 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl230,922,266 - 30,922,769 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1228,017,884 - 28,024,383 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0228,855,014 - 28,861,522 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,572,632 - 29,579,118 (-)NCBIUU_Cfam_GSD_1.0
UCN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11065,491,231 - 65,495,879 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21071,585,818 - 71,590,322 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UCN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.195,491,134 - 5,500,663 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl95,498,945 - 5,499,430 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605110,742,618 - 10,751,305 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ucn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624796130,924 - 131,886 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003827780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000015812   ⟹   ENSPPAP00000003433
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl105,405,683 - 5,406,168 (+)Ensembl
RefSeq Acc Id: XM_003827780   ⟹   XP_003827828
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2817,930,638 - 17,931,123 (+)NCBI
NHGRI_mPanPan11017,935,959 - 17,936,444 (+)NCBI
Mhudiblu_PPA_v0105,410,501 - 5,419,650 (+)NCBI
PanPan1.1105,398,032 - 5,406,168 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003827828 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003433
  ENSPPAP00000003433.1
Reference Protein Sequences
RefSeq Acc Id: XP_003827828   ⟸   XM_003827780
- UniProtKB: A0A2R8ZEH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000003433   ⟸   ENSPPAT00000015812
Protein Domains
Corticotropin-releasing factor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000014446 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000015812.1 UniProtKB/TrEMBL
InterPro CRF UniProtKB/TrEMBL
  Urocortin_II/III UniProtKB/TrEMBL
KEGG Report pps:100988979 UniProtKB/TrEMBL
NCBI Gene UCN3 ENTREZGENE
PANTHER PTHR17575 UniProtKB/TrEMBL
  UROCORTIN-3 UniProtKB/TrEMBL
Pfam CRF UniProtKB/TrEMBL
UniProt A0A2R8ZEH6 ENTREZGENE, UniProtKB/TrEMBL