S100A8 (S100 calcium binding protein A8) - Rat Genome Database

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Gene: S100A8 (S100 calcium binding protein A8) Pan paniscus
Analyze
Symbol: S100A8
Name: S100 calcium binding protein A8
RGD ID: 11872366
Description: ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent protein binding (inferred); metal ion binding (inferred); INVOLVED IN astrocyte development (ortholog); autocrine signaling (ortholog); chronic inflammatory response (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Animal Mammary Neoplasms (ortholog); atopic dermatitis (ortholog); FOUND IN calprotectin complex (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2196,446,588 - 96,447,727 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,182,294 - 96,183,433 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01128,741,378 - 128,742,520 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11132,370,435 - 132,371,591 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1132,370,435 - 132,371,591 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
S100A8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2196,446,588 - 96,447,727 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,182,294 - 96,183,433 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01128,741,378 - 128,742,520 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11132,370,435 - 132,371,591 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1132,370,435 - 132,371,591 (-)Ensemblpanpan1.1panPan2
S100A8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381153,390,032 - 153,422,583 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1153,390,032 - 153,391,073 (-)EnsemblGRCh38hg38GRCh38
GRCh371153,362,508 - 153,395,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361151,629,132 - 151,630,173 (-)NCBINCBI36Build 36hg18NCBI36
Build 341150,175,581 - 150,176,622NCBI
Celera1126,433,763 - 126,434,804 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1124,725,919 - 124,727,075 (-)NCBIHuRef
CHM1_11154,758,221 - 154,759,377 (-)NCBICHM1_1
T2T-CHM13v2.01152,527,256 - 152,559,808 (-)NCBIT2T-CHM13v2.0
S100a8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39390,576,378 - 90,577,341 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl390,576,285 - 90,577,342 (+)EnsemblGRCm39 Ensembl
GRCm38390,669,071 - 90,670,034 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl390,668,978 - 90,670,035 (+)EnsemblGRCm38mm10GRCm38
MGSCv37390,472,993 - 90,473,956 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36390,755,012 - 90,755,961 (+)NCBIMGSCv36mm8
Celera390,710,479 - 90,711,442 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.9NCBI
S100a8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82178,464,095 - 178,465,223 (+)NCBIGRCr8
mRatBN7.22176,166,517 - 176,167,645 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2176,167,124 - 176,167,643 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2183,307,416 - 183,307,935 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02181,329,670 - 181,330,189 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02175,929,499 - 175,930,018 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02190,073,239 - 190,074,333 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2190,073,815 - 190,074,354 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02209,507,598 - 209,508,692 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,961,994 - 182,962,513 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12182,912,099 - 182,912,619 (+)NCBI
Celera2170,099,876 - 170,100,395 (+)NCBICelera
Cytogenetic Map2q34NCBI
S100A8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1743,540,667 - 43,541,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl743,501,989 - 43,541,604 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha743,033,549 - 43,034,484 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0743,490,339 - 43,491,275 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl743,451,730 - 43,491,276 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1743,192,654 - 43,193,589 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0743,246,467 - 43,247,402 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0743,530,107 - 43,531,042 (+)NCBIUU_Cfam_GSD_1.0
S100a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505824,226,017 - 24,226,645 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365803,256,417 - 3,256,913 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365803,256,399 - 3,256,913 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
S100A8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl496,209,659 - 96,210,602 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1496,209,670 - 96,210,603 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24105,091,816 - 105,092,749 (-)NCBISscrofa10.2Sscrofa10.2susScr3
S100A8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12010,363,142 - 10,364,293 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2010,363,287 - 10,364,317 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660389,831,912 - 9,833,063 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
S100a8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624885784,528 - 785,623 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003817177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000060747   ⟹   ENSPPAP00000037845
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1132,370,435 - 132,371,591 (-)Ensembl
RefSeq Acc Id: XM_003817177   ⟹   XP_003817225
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2196,446,588 - 96,447,727 (+)NCBI
NHGRI_mPanPan1196,182,294 - 96,183,433 (+)NCBI
Mhudiblu_PPA_v01128,741,378 - 128,742,520 (-)NCBI
PanPan1.11132,370,435 - 132,371,591 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003817225 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000037845
  ENSPPAP00000037845.1
Reference Protein Sequences
RefSeq Acc Id: XP_003817225   ⟸   XM_003817177
- UniProtKB: A0A2R9C7E2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000037845   ⟸   ENSPPAT00000060747
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041657 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060747.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  S100/CaBP-9k_CS UniProtKB/TrEMBL
  S100_Ca-bd_sub UniProtKB/TrEMBL
KEGG Report pps:100993118 UniProtKB/TrEMBL
NCBI Gene S100A8 ENTREZGENE
PANTHER PTHR11639:SF5 UniProtKB/TrEMBL
  S100 CALCIUM-BINDING PROTEIN UniProtKB/TrEMBL
Pfam S_100 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  S100_CABP UniProtKB/TrEMBL
SMART S_100 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A2R9C7E2 ENTREZGENE, UniProtKB/TrEMBL