HCAR1 (hydroxycarboxylic acid receptor 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: HCAR1 (hydroxycarboxylic acid receptor 1) Pan paniscus
Analyze
Symbol: HCAR1
Name: hydroxycarboxylic acid receptor 1
RGD ID: 11869064
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); negative regulation of lipid catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210130,819,641 - 130,824,772 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112130,816,017 - 130,821,148 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012120,330,294 - 120,335,425 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112124,566,016 - 124,569,288 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12124,567,699 - 124,568,739 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA,ISO)
plasma membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HCAR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210130,819,641 - 130,824,772 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112130,816,017 - 130,821,148 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012120,330,294 - 120,335,425 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112124,566,016 - 124,569,288 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12124,567,699 - 124,568,739 (-)Ensemblpanpan1.1panPan2
HCAR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812122,726,076 - 122,730,844 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12122,726,076 - 122,730,844 (-)EnsemblGRCh38hg38GRCh38
GRCh3712123,210,623 - 123,215,391 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612121,778,106 - 121,781,082 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412121,735,610 - 121,740,009NCBI
Celera12122,804,963 - 122,807,939 (-)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12120,172,181 - 120,175,157 (-)NCBIHuRef
CHM1_112123,180,354 - 123,183,330 (-)NCBICHM1_1
T2T-CHM13v2.012122,721,458 - 122,726,228 (-)NCBIT2T-CHM13v2.0
Hcar1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395124,014,802 - 124,018,066 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5124,014,799 - 124,018,083 (-)EnsemblGRCm39 Ensembl
GRCm385123,876,739 - 123,880,003 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5123,876,736 - 123,880,020 (-)EnsemblGRCm38mm10GRCm38
MGSCv375124,326,745 - 124,330,029 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365124,137,596 - 124,140,621 (-)NCBIMGSCv36mm8
Celera5120,948,767 - 120,952,052 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map563.24NCBI
Hcar1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81238,371,593 - 38,374,847 (+)NCBIGRCr8
mRatBN7.21232,710,680 - 32,713,934 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,711,027 - 32,712,082 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1233,889,596 - 33,890,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01234,500,949 - 34,502,004 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01233,552,835 - 33,553,890 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01238,145,177 - 38,146,232 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,144,855 - 38,146,271 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01240,014,637 - 40,015,692 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,847,986 - 33,849,041 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1234,397,576 - 34,398,631 (+)NCBICelera
Cytogenetic Map12q15NCBI
Hcar1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554825,998,796 - 6,002,093 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554825,998,796 - 6,002,093 (+)NCBIChiLan1.0ChiLan1.0
HCAR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1266,734,818 - 6,735,906 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl266,734,818 - 6,735,906 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha266,895,785 - 6,896,873 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0266,984,011 - 6,985,099 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl266,983,610 - 6,986,835 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1266,915,982 - 6,917,070 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0267,009,736 - 7,010,824 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0266,963,158 - 6,964,246 (+)NCBIUU_Cfam_GSD_1.0
Hcar1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118157,585,480 - 157,589,414 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365581,890,439 - 1,891,480 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365581,890,027 - 1,893,632 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HCAR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1430,105,285 - 30,106,307 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11430,105,285 - 30,106,307 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21431,795,357 - 31,796,379 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HCAR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111118,055,943 - 118,087,946 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11118,056,603 - 118,057,643 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037127,260,574 - 127,264,069 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hcar1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474722,794,256 - 22,795,452 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474722,792,224 - 22,798,189 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000015538   ⟹   ENSPPAP00000003378
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl12124,567,699 - 124,568,739 (-)Ensembl
RefSeq Acc Id: XM_057299549   ⟹   XP_057155532
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210130,819,641 - 130,824,772 (-)NCBI
NHGRI_mPanPan112130,816,017 - 130,821,148 (-)NCBI
Protein Sequences
Protein RefSeqs XP_057155532 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein APT70317 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003378.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000003378   ⟸   ENSPPAT00000015538
RefSeq Acc Id: XP_057155532   ⟸   XM_057299549
- UniProtKB: A0A2R8ZEB9 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000014195 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000015538.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report pps:100986073 UniProtKB/TrEMBL
NCBI Gene HCAR1 ENTREZGENE
PANTHER HYDROXYCARBOXYLIC ACID RECEPTOR 2 UniProtKB/TrEMBL
  PTHR46048:SF3 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A2R8ZEB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4Y1JWL8_PANPA UniProtKB/TrEMBL