ECT2L (epithelial cell transforming 2 like) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: ECT2L (epithelial cell transforming 2 like) Pan paniscus
Analyze
Symbol: ECT2L
Name: epithelial cell transforming 2 like
RGD ID: 11867786
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); ASSOCIATED WITH Familial Behcet-Like Autoinflammatory Syndrome (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: epithelial cell transforming sequence 2 oncogene-like; epithelial cell-transforming sequence 2 oncogene-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25158,762,241 - 158,868,220 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16156,659,827 - 156,766,511 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06136,556,048 - 136,662,697 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16140,641,624 - 140,747,937 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6140,641,624 - 140,748,058 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ECT2L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25158,762,241 - 158,868,220 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16156,659,827 - 156,766,511 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06136,556,048 - 136,662,697 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16140,641,624 - 140,747,937 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6140,641,624 - 140,748,058 (+)Ensemblpanpan1.1panPan2
ECT2L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386138,796,087 - 138,904,070 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6138,795,911 - 138,904,070 (+)EnsemblGRCh38hg38GRCh38
GRCh376139,117,224 - 139,225,207 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366139,176,002 - 139,266,900 (+)NCBINCBI36Build 36hg18NCBI36
Celera6139,857,349 - 139,965,590 (+)NCBICelera
Cytogenetic Map6q24.1NCBI
HuRef6136,678,549 - 136,786,853 (+)NCBIHuRef
CHM1_16139,380,248 - 139,488,189 (+)NCBICHM1_1
T2T-CHM13v2.06139,984,635 - 140,092,615 (+)NCBIT2T-CHM13v2.0
Ect2l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391018,004,123 - 18,086,575 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1018,004,651 - 18,086,638 (-)EnsemblGRCm39 Ensembl
GRCm381018,128,375 - 18,210,827 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1018,128,903 - 18,210,890 (-)EnsemblGRCm38mm10GRCm38
MGSCv371017,848,828 - 17,921,159 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361017,848,828 - 17,921,159 (-)NCBIMGSCv36mm8
Celera1018,027,165 - 18,098,726 (-)NCBICelera
Cytogenetic Map10A3NCBI
cM Map107.47NCBI
Ect2l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8114,594,726 - 14,677,321 (-)NCBIGRCr8
mRatBN7.2112,775,705 - 12,857,538 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl112,778,922 - 12,855,449 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0113,301,918 - 13,372,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl113,302,256 - 13,341,952 (-)EnsemblRnor6.0rn6Rnor6.0
Celera111,234,398 - 11,301,711 (-)NCBICelera
Cytogenetic Map1p12NCBI
Ect2l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543620,754,934 - 20,843,015 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543620,754,395 - 20,843,015 (-)NCBIChiLan1.0ChiLan1.0
ECT2L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1131,069,668 - 31,140,358 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl131,069,732 - 31,139,325 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha131,937,114 - 32,015,831 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0131,223,419 - 31,303,208 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl131,232,949 - 31,300,641 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1131,110,418 - 31,179,588 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0130,982,991 - 31,061,831 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0131,292,668 - 31,372,882 (+)NCBIUU_Cfam_GSD_1.0
Ect2l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946126,111,158 - 126,199,922 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365605,906,220 - 5,978,849 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365605,906,173 - 5,979,080 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECT2L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,566,954 - 25,644,277 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,566,955 - 25,644,289 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2128,702,374 - 28,779,562 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ECT2L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11334,489,321 - 34,594,872 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1334,491,222 - 34,576,744 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660406,660,068 - 6,768,969 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ect2l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475315,059,107 - 15,150,617 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475315,058,307 - 15,153,975 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000054381   ⟹   ENSPPAP00000031516
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6140,641,624 - 140,748,058 (+)Ensembl
RefSeq Acc Id: XM_003827709   ⟹   XP_003827757
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25158,762,241 - 158,868,220 (+)NCBI
NHGRI_mPanPan16156,659,827 - 156,766,511 (+)NCBI
Mhudiblu_PPA_v06136,556,048 - 136,662,697 (+)NCBI
PanPan1.16140,641,624 - 140,747,937 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055114159   ⟹   XP_054970134
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25158,774,456 - 158,868,220 (+)NCBI
NHGRI_mPanPan16156,672,030 - 156,766,511 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003827757 (Get FASTA)   NCBI Sequence Viewer  
  XP_054970134 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000031516.1
Reference Protein Sequences
RefSeq Acc Id: XP_003827757   ⟸   XM_003827709
- Sequence:
RefSeq Acc Id: ENSPPAP00000031516   ⟸   ENSPPAT00000054381
RefSeq Acc Id: XP_054970134   ⟸   XM_055114159
Protein Domains
DH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038702 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054381.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  DUF4347 UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100970740 UniProtKB/TrEMBL
NCBI Gene ECT2L ENTREZGENE
PANTHER EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE UniProtKB/TrEMBL
  EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE UniProtKB/TrEMBL
Pfam DUF4347 UniProtKB/TrEMBL
  F-box-like UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PROSITE DH_2 UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48065 UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A2R9BPC5_PANPA UniProtKB/TrEMBL