SNAI2 (snail family transcriptional repressor 2) - Rat Genome Database

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Gene: SNAI2 (snail family transcriptional repressor 2) Pan paniscus
Analyze
Symbol: SNAI2
Name: snail family transcriptional repressor 2
RGD ID: 11866175
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cartilage morphogenesis (ortholog); cell migration (ortholog); cell migration involved in endocardial cushion formation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); calcinosis (ortholog); Esophageal Neoplasms (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: snail homolog 2; zinc finger protein SNAI2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1842,727,135 - 42,730,736 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl842,723,971 - 42,730,904 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0845,341,857 - 45,345,544 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cartilage morphogenesis  (ISO)
cell migration  (ISO)
cell migration involved in endocardial cushion formation  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to ionizing radiation  (ISO)
desmosome disassembly  (ISO)
epithelial to mesenchymal transition  (ISO)
epithelial to mesenchymal transition involved in endocardial cushion formation  (ISO)
epithelium development  (ISO)
negative regulation of anoikis  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of canonical Wnt signaling pathway  (ISO)
negative regulation of cell adhesion involved in substrate-bound cell migration  (ISO)
negative regulation of cell adhesion mediated by integrin  (ISO)
negative regulation of chondrocyte differentiation  (ISO)
negative regulation of DNA damage response, signal transduction by p53 class mediator  (ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
negative regulation of keratinocyte proliferation  (ISO)
negative regulation of stem cell proliferation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of vitamin D biosynthetic process  (ISO)
negative regulation of vitamin D receptor signaling pathway  (ISO)
neural crest cell development  (ISO)
Notch signaling pathway  (ISO)
osteoblast differentiation  (ISO)
pigmentation  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of fat cell differentiation  (ISO)
positive regulation of histone acetylation  (ISO)
regulation of bicellular tight junction assembly  (ISO)
regulation of branching involved in salivary gland morphogenesis  (ISO)
regulation of chemokine production  (ISO)
regulation of osteoblast differentiation  (ISO)
response to radiation  (ISO)
roof of mouth development  (ISO)
sensory perception of sound  (ISO)
substrate-dependent cell migration  (ISO)
white fat cell differentiation  (ISO)

Cellular Component
chromatin  (ISO)
cytoplasm  (ISO)
nucleus  (ISO)

References

Genomics

Comparative Map Data
SNAI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1842,727,135 - 42,730,736 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl842,723,971 - 42,730,904 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0845,341,857 - 45,345,544 (-)NCBIMhudiblu_PPA_v0panPan3
SNAI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl848,917,598 - 48,921,740 (-)EnsemblGRCh38hg38GRCh38
GRCh38848,917,598 - 48,921,429 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37849,830,157 - 49,833,988 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36849,992,789 - 49,996,541 (-)NCBINCBI36hg18NCBI36
Build 34849,992,795 - 49,996,541NCBI
Celera845,817,447 - 45,821,199 (-)NCBI
Cytogenetic Map8q11.21NCBI
HuRef845,294,292 - 45,298,055 (-)NCBIHuRef
CHM1_1849,882,550 - 49,886,313 (-)NCBICHM1_1
Snai2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391614,523,716 - 14,527,259 (+)NCBIGRCm39mm39
GRCm39 Ensembl1614,523,716 - 14,527,249 (+)Ensembl
GRCm381614,705,852 - 14,709,395 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1614,705,852 - 14,709,385 (+)EnsemblGRCm38mm10GRCm38
MGSCv371614,705,952 - 14,709,478 (+)NCBIGRCm37mm9NCBIm37
MGSCv361614,619,437 - 14,622,963 (+)NCBImm8
Celera1615,292,698 - 15,296,242 (+)NCBICelera
Cytogenetic Map16A1NCBI
cM Map1610.07NCBI
Snai2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21186,183,800 - 86,186,109 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1186,181,909 - 86,186,200 (-)Ensembl
Rnor_6.01190,404,421 - 90,406,730 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1190,403,333 - 90,406,797 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01193,462,645 - 93,464,954 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1184,915,524 - 84,917,833 (-)NCBICelera
Cytogenetic Map11q23NCBI
Snai2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554548,758,636 - 8,764,427 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554548,759,860 - 8,763,603 (-)NCBIChiLan1.0ChiLan1.0
SNAI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1291,154,132 - 1,156,653 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl291,154,036 - 1,156,653 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha291,580,366 - 1,582,888 (-)NCBI
ROS_Cfam_1.0291,209,732 - 1,213,335 (-)NCBI
UMICH_Zoey_3.1291,151,831 - 1,154,347 (-)NCBI
UNSW_CanFamBas_1.0291,378,544 - 1,381,065 (-)NCBI
UU_Cfam_GSD_1.0291,416,068 - 1,418,591 (-)NCBI
Snai2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530378,624,121 - 78,627,846 (+)NCBI
SpeTri2.0NW_0049365903,813,916 - 3,817,642 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNAI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl479,264,878 - 79,268,475 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1479,264,880 - 79,268,475 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2486,680,198 - 86,683,793 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SNAI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1845,043,381 - 45,047,054 (-)NCBI
ChlSab1.1 Ensembl845,043,393 - 45,046,978 (-)Ensembl
Vero_WHO_p1.0NW_02366603996,972,541 - 96,976,202 (+)NCBI
Snai2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247356,594,564 - 6,598,288 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003823263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000017162   ⟹   ENSPPAP00000003717
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl842,723,971 - 42,730,904 (-)Ensembl
RefSeq Acc Id: XM_003823263   ⟹   XP_003823311
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1842,727,135 - 42,730,736 (-)NCBI
Mhudiblu_PPA_v0845,341,857 - 45,345,544 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003823311 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003823311   ⟸   XM_003823263
- Sequence:
RefSeq Acc Id: ENSPPAP00000003717   ⟸   ENSPPAT00000017162


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000015662 Ensembl, ENTREZGENE
Ensembl Protein ENSPPAP00000003717 ENTREZGENE
NCBI Gene SNAI2 ENTREZGENE