GABRG3 (gamma-aminobutyric acid type A receptor subunit gamma3) - Rat Genome Database

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Gene: GABRG3 (gamma-aminobutyric acid type A receptor subunit gamma3) Pan paniscus
Analyze
Symbol: GABRG3
Name: gamma-aminobutyric acid type A receptor subunit gamma3
RGD ID: 11863013
Description: ENCODES a protein that exhibits chloride channel activity (ortholog); GABA-A receptor activity (ortholog); INVOLVED IN response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Angelman syndrome (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN GABA-ergic synapse (ortholog); synaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: gamma-aminobutyric acid receptor subunit gamma-3; gamma-aminobutyric acid type A receptor gamma3 subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2167,748,343 - 8,306,630 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11511,389,636 - 11,947,679 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0152,371,468 - 2,932,250 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11524,703,846 - 24,960,913 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1524,409,611 - 24,959,987 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GABRG3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2167,748,343 - 8,306,630 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11511,389,636 - 11,947,679 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0152,371,468 - 2,932,250 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11524,703,846 - 24,960,913 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1524,409,611 - 24,959,987 (+)Ensemblpanpan1.1panPan2
GABRG3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381526,971,181 - 27,541,984 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1526,971,181 - 27,541,984 (+)EnsemblGRCh38hg38GRCh38
GRCh371527,216,328 - 27,787,130 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361525,399,391 - 25,451,729 (+)NCBINCBI36Build 36hg18NCBI36
Build 361524,799,263 - 25,168,899 (+)NCBINCBI36Build 36hg18NCBI36
Build 341525,399,390 - 25,451,722NCBI
Celera155,377,602 - 5,938,310 (+)NCBICelera
Cytogenetic Map15q12NCBI
HuRef155,344,440 - 5,905,082 (+)NCBIHuRef
CHM1_11527,165,969 - 27,727,967 (+)NCBICHM1_1
T2T-CHM13v2.01524,712,759 - 25,284,426 (+)NCBIT2T-CHM13v2.0
Gabrg3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39756,366,211 - 57,037,173 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl756,366,213 - 57,036,936 (-)EnsemblGRCm39 Ensembl
GRCm38756,716,463 - 57,387,215 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl756,716,465 - 57,387,188 (-)EnsemblGRCm38mm10GRCm38
MGSCv37763,979,612 - 64,642,241 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36756,592,261 - 57,254,817 (-)NCBIMGSCv36mm8
Celera754,048,949 - 54,699,615 (-)NCBICelera
Cytogenetic Map7B5NCBI
cM Map733.48NCBI
Gabrg3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81116,763,332 - 117,386,770 (-)NCBIGRCr8
mRatBN7.21107,627,450 - 108,247,483 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1107,627,390 - 108,246,763 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1113,001,526 - 113,624,939 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01121,473,413 - 122,097,448 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01114,722,366 - 115,345,770 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01112,158,525 - 112,812,267 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1112,158,519 - 112,811,936 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01113,167,714 - 113,822,248 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41108,189,311 - 108,821,051 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11108,267,653 - 108,899,394 (-)NCBI
Celera1101,806,875 - 102,419,541 (-)NCBICelera
Cytogenetic Map1q22NCBI
Gabrg3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555331,962,273 - 2,495,876 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555331,962,175 - 2,495,877 (-)NCBIChiLan1.0ChiLan1.0
GABRG3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1332,956,061 - 33,641,971 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl332,964,122 - 33,642,686 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha335,646,875 - 36,332,262 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0333,293,570 - 33,977,676 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl333,300,191 - 33,978,514 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1332,834,310 - 33,518,364 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0333,083,854 - 33,780,951 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0333,186,801 - 33,927,787 (-)NCBIUU_Cfam_GSD_1.0
Gabrg3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640121,329,746 - 121,903,607 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647139,185,702 - 39,751,187 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647139,184,683 - 39,256,439 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABRG3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1139,857,095 - 140,464,579 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11139,855,461 - 140,464,592 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21156,085,367 - 156,136,061 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GABRG3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12654,570,497 - 55,126,712 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605437,445,615 - 37,956,789 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabrg3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248961,392,932 - 1,973,363 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000049970   ⟹   ENSPPAP00000027132
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1524,409,611 - 24,959,987 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000049973   ⟹   ENSPPAP00000027135
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1524,705,744 - 24,959,987 (+)Ensembl
RefSeq Acc Id: XM_034938408   ⟹   XP_034794299
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2167,748,343 - 8,306,630 (-)NCBI
NHGRI_mPanPan11511,389,636 - 11,947,679 (-)NCBI
Mhudiblu_PPA_v0152,375,373 - 2,932,100 (-)NCBI
RefSeq Acc Id: XM_034938409   ⟹   XP_034794300
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2167,748,343 - 8,306,628 (-)NCBI
NHGRI_mPanPan11511,389,636 - 11,947,679 (-)NCBI
Mhudiblu_PPA_v0152,371,468 - 2,932,250 (-)NCBI
RefSeq Acc Id: XM_055098678   ⟹   XP_054954653
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2167,748,343 - 8,005,887 (-)NCBI
NHGRI_mPanPan11511,389,636 - 11,647,035 (-)NCBI
RefSeq Acc Id: XM_055098679   ⟹   XP_054954654
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2167,748,343 - 8,005,873 (-)NCBI
NHGRI_mPanPan11511,389,636 - 11,647,021 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034794299 (Get FASTA)   NCBI Sequence Viewer  
  XP_034794300 (Get FASTA)   NCBI Sequence Viewer  
  XP_054954653 (Get FASTA)   NCBI Sequence Viewer  
  XP_054954654 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000027132.1
  ENSPPAP00000027135.1
Reference Protein Sequences
RefSeq Acc Id: XP_034794300   ⟸   XM_034938409
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BD98 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034794299   ⟸   XM_034938408
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BD98 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000027132   ⟸   ENSPPAT00000049970
RefSeq Acc Id: ENSPPAP00000027135   ⟸   ENSPPAT00000049973
RefSeq Acc Id: XP_054954653   ⟸   XM_055098678
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BK69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054954654   ⟸   XM_055098679
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BK69 (UniProtKB/TrEMBL)
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036643 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049970.1 UniProtKB/TrEMBL
  ENSPPAT00000049973.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/TrEMBL
InterPro GABAA/Glycine_rcpt UniProtKB/TrEMBL
  GABBAg3_rcpt UniProtKB/TrEMBL
  GABBAg_rcpt UniProtKB/TrEMBL
  Neur_chan_lig-bd UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/TrEMBL
  Neur_channel UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/TrEMBL
NCBI Gene GABRG3 ENTREZGENE
PANTHER GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-3 UniProtKB/TrEMBL
  PTHR18945 UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/TrEMBL
PRINTS GABAARECEPTR UniProtKB/TrEMBL
  GABAARGAMMA UniProtKB/TrEMBL
  GABAARGAMMA3 UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/TrEMBL
  SSF90112 UniProtKB/TrEMBL
UniProt A0A2R9BD98 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BK69 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 GABRG3  gamma-aminobutyric acid type A receptor subunit gamma3  GABRG3  gamma-aminobutyric acid type A receptor gamma3 subunit  Symbol and/or name change 5135510 APPROVED